4.7 Article

Discovery of Novel Plasmodium falciparum HDAC1 Inhibitors with Dual-Stage Antimalarial Potency and Improved Safety Based on the Clinical Anticancer Drug Candidate Quisinostat

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Editorial Material Medicine, General & Internal

A Temporizing Solution to Artemisinin Resistance

Jigang Wang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Review Oncology

The timeline of epigenetic drug discovery: from reality to dreams

A. Ganesan et al.

CLINICAL EPIGENETICS (2019)

Article Chemistry, Medicinal

Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives

Gebremedhin S. Hailu et al.

JOURNAL OF MEDICINAL CHEMISTRY (2017)

Review Biochemistry & Molecular Biology

Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic

Benjamin Blasco et al.

NATURE MEDICINE (2017)

Article Parasitology

Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth

Ming Jang Chua et al.

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE (2017)

Review Biochemistry & Molecular Biology

Malaria: Biology and Disease

Alan F. Cowman et al.

Editorial Material Pharmacology & Pharmacy

The utilization of spirocyclic scaffolds in novel drug discovery

Ya-Jun Zheng et al.

EXPERT OPINION ON DRUG DISCOVERY (2016)

Article Biochemistry & Molecular Biology

Small-molecule targeting of a diapophytoene desaturase inhibits S. aureus virulence

Feifei Chen et al.

NATURE CHEMICAL BIOLOGY (2016)

Article Chemistry, Medicinal

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs

Jesus M. Ontoria et al.

ACS MEDICINAL CHEMISTRY LETTERS (2016)

Letter Immunology

Artemisinin-Resistant Plasmodium falciparum K13 Mutant Alleles, Thailand-Myanmar Border

Mikael Boulle et al.

EMERGING INFECTIOUS DISEASES (2016)

Article Chemistry, Medicinal

Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite

Giuseppe Giannini et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)

Article Biotechnology & Applied Microbiology

Hit and lead criteria in drug discovery for infectious diseases of the developing world

Kei Katsuno et al.

NATURE REVIEWS DRUG DISCOVERY (2015)

Article Chemistry, Medicinal

The use of spirocyclic scaffolds in drug discovery

Yajun Zheng et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)

Article Microbiology

Heterochromatin Protein 1 Secures Survival and Transmission of Malaria Parasites

Nicolas M. B. Brancucci et al.

CELL HOST & MICROBE (2014)

Article Chemistry, Medicinal

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages

Finn K. Hansen et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)

Article Biotechnology & Applied Microbiology

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

Mehdi Ghorbal et al.

NATURE BIOTECHNOLOGY (2014)

Article Parasitology

Antimalarial drug discovery - the path towards eradication

Jeremy N. Burrows et al.

PARASITOLOGY (2014)

Article Multidisciplinary Sciences

Targeting Plasmodium PI(4)K to eliminate malaria

Case W. McNamara et al.

NATURE (2013)

Article Multidisciplinary Sciences

Inducible Knockdown of Plasmodium Gene Expression Using the glmS Ribozyme

Parichat Prommana et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Sir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparum

Liliana Mancio-Silva et al.

NATURE COMMUNICATIONS (2013)

Article Microbiology

Antimalarial Activity of the Anticancer Histone Deacetylase Inhibitor SB939

Subathdrage D. M. Sumanadasa et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)

Article Pharmacology & Pharmacy

Towards Histone Deacetylase Inhibitors as New Antimalarial Drugs

K Andrews

CURRENT PHARMACEUTICAL DESIGN (2012)

Review Cell Biology

HDAC inhibitors in parasitic diseases

Katherine T. Andrews et al.

IMMUNOLOGY AND CELL BIOLOGY (2012)

Article Chemistry, Medicinal

Non-Peptide Macrocyclic Histone Deacetylase Inhibitors Derived from Tricyclic Ketolide Skeleton

Sandra C. Mwakwari et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum

Christopher J. Tonkin et al.

PLOS BIOLOGY (2009)

Article Microbiology

Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors

Geoffrey S. Dow et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)

Article Cell Biology

Differential association of Orc1 and Sir2 proteins to telomeric domains in Plasmodium falciparum

Liliana Mancio-Silva et al.

JOURNAL OF CELL SCIENCE (2008)

Article Biochemistry & Molecular Biology

A calcium-dependent protein kinase regulates Plasmodium ookinete access to the midgut epithelial cell

T Ishino et al.

MOLECULAR MICROBIOLOGY (2006)

Article Biochemistry & Molecular Biology

High efficiency transfection of Plasmodium berghei facilitates novel selection procedures

CJ Janse et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2006)

Article Microbiology

Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening

M Smilkstein et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

Article Parasitology

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents

KT Andrews et al.

INTERNATIONAL JOURNAL FOR PARASITOLOGY (2000)