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Chikungunya Virus Induces IPS-1-Dependent Innate Immune Activation and Protein Kinase R-Independent Translational Shutoff
Laura K. White et al.
JOURNAL OF VIROLOGY (2011)
Blocking eIF4E-eIF4G Interaction as a Strategy To Impair Coronavirus Replication
Regina Cencic et al.
JOURNAL OF VIROLOGY (2011)
Receptor Tyrosine Kinase Inhibitors Block Multiple Steps of Influenza A Virus Replication
Naveen Kumar et al.
JOURNAL OF VIROLOGY (2011)
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy
Joachim Lupberger et al.
NATURE MEDICINE (2011)
Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia
S. Hart et al.
BLOOD CANCER JOURNAL (2011)
High-Content Assay to Identify Inhibitors of Dengue Virus Infection
David Shum et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2010)
Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms
Alfonso Quintas-Cardama et al.
BLOOD (2010)
Metabolism, Excretion, and Pharmacokinetics of [14C]INCB018424, a Selective Janus Tyrosine Kinase 1/2 Inhibitor, in Humans
Adam D. Shilling et al.
DRUG METABOLISM AND DISPOSITION (2010)
Randomized, Double-Blind, Placebo-Controlled Trial of the Oral Interleukin-12/23 Inhibitor Apilimod Mesylate for Treatment of Active Crohn's Disease
Bruce E. Sands et al.
INFLAMMATORY BOWEL DISEASES (2010)
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors
Jianming Zhang et al.
NATURE (2010)
Epidermal growth factor receptor is a co-receptor for adeno-associated virus serotype 6
Melodie L. Weller et al.
NATURE MEDICINE (2010)
Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis.
Srdan Verstovsek et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Anti-BK Virus Mechanisms of Sirolimus and Leflunomide Alone and in Combination: Toward a New Therapy for BK Virus Infection
Abdelhamid Liacini et al.
TRANSPLANTATION (2010)
Inhibition of human immunodeficiency virus type-1 by cdk inhibitors
Irene Guendel et al.
AIDS RESEARCH AND THERAPY (2010)
Chemical Library Screens Targeting an HIV-1 Accessory factor/Host Cell Kinase Complex Identify Novel Antiretroviral Compounds
Lori Emert-Sedlak et al.
ACS CHEMICAL BIOLOGY (2009)
Identification of Novel Cellular Targets for Therapeutic Intervention Against Ebola Virus Infection by siRNA Screening
Andrey A. Kolokoltsov et al.
DRUG DEVELOPMENT RESEARCH (2009)
Seliciclib in malignancies
Ibrahim T. Aldoss et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2009)
New aspects of an anti-tumour drug: sorafenib efficiently inhibits HCV replication
K. Himmelsbach et al.
GUT (2009)
Participation of the phosphatidylinositol 3-kinase/Akt pathway in Junin virus replication in vitro
F. N. Linero et al.
VIRUS RESEARCH (2009)
Inhibition of human coronavirus 229E infection in human epithelial lung cells (L132) by chloroquine: Involvement of p38 MAPK and ERK
Masakazu Kono et al.
ANTIVIRAL RESEARCH (2008)
Genistein treatment of cells inhibits arenavirus infection
Eric M. Vela et al.
ANTIVIRAL RESEARCH (2008)
Role of cdk9 in the Optimization of Expression of the Genes Regulated by ICP22 of Herpes Simplex Virus 1
Lizette Olga Durand et al.
JOURNAL OF VIROLOGY (2008)
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus
Mohammad F. Saeed et al.
PLOS PATHOGENS (2008)
Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening
Lubica Supekova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Discovery and preclinical characterization of INCB018424, a selective JAK2 inhibitor for the treatment of myeloproliferative disorders
Jordan Fridman et al.
BLOOD (2007)
The ERK mitogen-activated protein kinase pathway contributes to Ebola virus glycoprotein-induced cytotoxicity
Carisa A. Zampieri et al.
JOURNAL OF VIROLOGY (2007)
The tyrosine kinase inhibitor genistein blocks HIV-1 infection in primary human macrophages
Tzanko S. Stantchev et al.
VIRUS RESEARCH (2007)
Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication
T Bürckstümmer et al.
FEBS LETTERS (2006)
Down-regulation of the tumor suppressor gene C-terminal Src kinase: An early event during premalignant colonic epithelial hyperproliferation
DP Kunte et al.
FEBS LETTERS (2005)
Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases
PM Reeves et al.
NATURE MEDICINE (2005)
Leflunomide for polyomavirus type BK nephropathy
JW Williams et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Imatinib-induced regression of AIDS-related Kaposi's sarcoma
HB Koon et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae
EM Damm et al.
JOURNAL OF CELL BIOLOGY (2005)
Antiviral activity of CYC202 in HIV-1-infected cells
E Agbottah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
MEK inhibition impairs influenza B virus propagation without emergence of resistant variants
S Ludwig et al.
FEBS LETTERS (2004)
Viral and cellular kinases are potential antiviral targets and have a central role in varicella zoster virus pathogenesis
JF Moffat et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2004)
Effects of pharmacological cyclin-dependent kinase inhibitors on viral transcription and replication
LM Schang
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2004)
From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-pliosphoinositide-dependent protein kinase-1 inhibitors (Publication with Expression of Concern. See vol. 79, pg. 1716, 2019)
JX Zhu et al.
CANCER RESEARCH (2004)
Cyclin-dependent kinase activity is required at early times for accurate processing and accumulation of the human cytomegalovirus UL122-123 and UL37 immediate-early transcripts and at later times for virus production
V Sanchez et al.
JOURNAL OF VIROLOGY (2004)
Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus
X Wang et al.
NATURE (2003)
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint
S Hauf et al.
JOURNAL OF CELL BIOLOGY (2003)
Influenza-virus-induced signaling cascades: targets for antiviral therapy?
S Ludwig et al.
TRENDS IN MOLECULAR MEDICINE (2003)
Cyclin-dependent kinases as cellular targets for antiviral drugs
LM Schang
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2002)
Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type I by targeting cellular, not viral, proteins
LM Schang et al.
JOURNAL OF VIROLOGY (2002)
MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells
O Planz et al.
JOURNAL OF VIROLOGY (2001)
Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade
S Pleschka et al.
NATURE CELL BIOLOGY (2001)
BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells
M Egeblad et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Entry of influenza viruses into cells is inhibited by a highly specific protein kinase C inhibitor
CN Root et al.
JOURNAL OF GENERAL VIROLOGY (2000)
Flavopiridol inhibits P-TEFb and blocks HIV-1 replication
SH Chao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cyclin-dependent kinases inhibitors as potential anticancer, antineurodegenerative, antiviral and antiparasitic agents
L Meijer
DRUG RESISTANCE UPDATES (2000)