4.2 Article

A NEW RING STENT WITH GRADED GEOMETRY FOR TREATING COARCTATION OF CURVED AORTA ARTERIES

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出版社

WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S0219519421500147

关键词

In-stent restenosis; ring-and-link stent; curved arteries; graded geometry; peak stress

资金

  1. National Natural Science Foundation of China [51575377, 51721003]

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The proposed graded ring stent shows potential in reducing the risk of in-stent restenosis by decreasing the peak stress exerted on curved arteries.
Ring stent implantation has been widely used to treat coarctation of the aorta (CoA) as an alternative to surgery. Currently adopted stents with uniform geometry may cause uneven stress distribution and high stress concentration in curved vessels, leading to in-stent restenosis (ISR). Inspired by functional graded material, here we propose a new ring-and-link stent, which has graded geometry in order to achieve a reduced peak stress when deployed in curved arteries. Numerical simulation of a single ring of the graded stent indicated that by varying the circumferential spacing of wave crest, the maximum stress exerted on the artery was reduced by as much as 27.86% in comparison with the uniform one. The effects of stent geometric parameters and artery curvature were also obtained through a parametric study. Finally, a whole stent was studied to verify the design, and a maximum stress reduction by 31.96% was achieved. In summary, the proposed graded ring stent shows great potential in clinical applications to reduce the risk of ISR.

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