Treatment of Actinic Keratosis: Does Effectiveness Depend on the Location?

This is a comment on a network meta-analysis that evaluated the ranking of treatments for actinic keratosis outside the head and neck. The results of a limited number of heterogeneous studies contrast with the results of studies in the head and neck area. The extent to which these results can be generalized to larger treatment fields or areas with extensive field cancerization is uncertain.

Automated summary

This comment discusses a network meta-analysis evaluating the ranking of treatments for actinic keratosis outside the head and neck. The limited and heterogeneous studies contrast with those in the head and neck area, raising uncertainty about generalizability to larger treatment fields or areas with extensive field cancerization.