Four keys to unlock IgG

The identification of discrete subclasses within the immunoglobulin G (IgG) isotype by Grey and Kunkel (1964. J. Exp. Med. https://doi.org/10.1084/jem.120.2.253) provided the framework for our current understanding of differential IgG subclass activity in protective and self-reactive immune responses.

Automated summary

The study by Grey and Kunkel in 1964 laid the groundwork for our current understanding of the differential IgG subclass activity in protective and self-reactive immune responses.