相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Selumetinib in Children with Inoperable Plexiform Neurofibromas
Andrea M. Gross et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors
Mark C. de Gooijer et al.
INTERNATIONAL JOURNAL OF CANCER (2018)
Patient-reported outcomes of pain and physical functioning in neurofibromatosis clinical trials
Pamela L. Wolters et al.
NEUROLOGY (2016)
Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas
Eva Dombi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Pain Interference in Youth with Neurofibromatosis Type 1 and Plexiform Neurofibromas and Relation to Disease Severity, Social-Emotional Functioning, and Quality of Life
Pamela L. Wolters et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2015)
Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1
Edwin Jousma et al.
PEDIATRIC BLOOD & CANCER (2015)
Development of the Adult PedsQL™ Neurofibromatosis Type 1 Module: Initial Feasibility, Reliability and Validity
Kavitha Nutakki et al.
HEALTH AND QUALITY OF LIFE OUTCOMES (2013)
Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy
Libero Santarpia et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2012)
Pilot study of PD-0325901 in previously treated patients with advanced melanoma, breast cancer, and colon cancer
Peter D. Boasberg et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Following Nerve Injury Neuregulin-1 Drives Microglial Proliferation and Neuropathic Pain via the MEK/ERK Pathway
Margarita Calvo et al.
GLIA (2011)
Molecular and Cellular Mechanisms of Learning Disabilities: A Focus on NF1
C. Shilyansky et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 33 (2010)
Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral MAPK/ERK Kinase Inhibitor PD-0325901 in Patients with Advanced Cancers
Patricia M. LoRusso et al.
CLINICAL CANCER RESEARCH (2010)
Neurofibromin Regulation of ERK Signaling Modulates GABA Release and Learning
Yijun Cui et al.
CELL (2008)
NF1 plexiform neurofibroma growth rate by volumetric MRI - Relationship to age and body weight
E. Dombi et al.
NEUROLOGY (2007)
ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model
ZY Zhuang et al.
PAIN (2005)
ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity
RR Ji et al.
JOURNAL OF NEUROSCIENCE (2002)
Defining the clinically important difference in pain outcome measures
JT Farrar et al.
PAIN (2000)