期刊
JOURNAL OF CLINICAL EPIDEMIOLOGY
卷 136, 期 -, 页码 26-36出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jclinepi.2021.03.003
关键词
Core outcome set; COS; Patient-reported outcome measure; PRO; PROM; Outcomes research
资金
- Innovative Medicines Initiative 2 Joint Undertaking [116055]
- European Union
- European Federation of Pharmaceutical Industries and Associations (EFPIA)
- National Institute for Health Research (NIHR) [NF-SI_0513-10025]
- MRC Trials Methodology Research Partnership [MR/S014357/1]
- MRC [MR/S014357/1] Funding Source: UKRI
This study reviewed core outcome sets (COS) with patient-reported outcomes measures (PROMs) and found that while most instruments cover broad health-related constructs, there are issues of resource overlap within and across different disease areas.
Objective: There is no comprehensive assessment of which patient-reported outcomes (PROs) are recommended in core outcome sets (COS), and how they should be measured. The aims of this study are to review COS that include patient-reported outcomes measures (PROMs), identify their target health domains, main characteristics, and their overlap within and across different disease areas. Study design and setting: We selected COS studies collected in a publicly available database that included at least one recommended PROM. We gathered information on study setting, disease area, and targeted outcome domains. Full-text of recommended instruments were obtained, and an analysis of their characteristics and content performed. We classified targeted domains according to a predefined 38-item taxonomy. Results: Overall, we identified 94 COS studies that recommended 323 unique instruments, of which: 87% were included in only one COS; 77% were disease-specific; 1.5% preference-based; and 61% corresponded to a full questionnaire. Most of the instruments covered broad health-related constructs, such as global quality of life (25%), physical functioning (22%), emotional functioning and wellbeing (7%). Conclusion: The wealth of recommended instruments observed even within disease areas does not fit with a vision of systematic, harmonized collection of PROM data in COS within and across disease areas. (c) 2021 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据