Molecular targeted treatment and drug delivery system for gastric cancer

Gastric cancer is still a major cancer worldwide. The early diagnosis rate of gastric cancer in most high incidence countries is low. At present, the overall treatment effect of gastric cancer is poor, and the median overall survival remains low. Most of the patients with gastric cancer are in an advanced stage when diagnosed, and drug treatment has become the main means. Thus, new targeted drugs and therapeutic strategies are the hope of improving the therapeutic effect of gastric cancer. In this review, we summarize the new methods and advances of targeted therapy for gastric cancer, including novel molecular targeted therapeutic agents and drug delivery systems, with a major focus on the development of drug delivery systems (drug carriers and targeting peptides). Elaborating these new methods and advances will contribute to the management of gastric cancer.

Automated summary

Gastric cancer remains a major cancer globally with low early diagnosis rates and poor overall treatment effects. Most patients are diagnosed in advanced stages, leading to drug treatment as the main approach. Developing new targeted drugs and therapeutic strategies is crucial for improving the management of gastric cancer.