期刊
JOURNAL OF BIOPHOTONICS
卷 14, 期 5, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jbio.202000475
关键词
bulk tissue; depolarization; histopathology; Mueller matrix; polarimetric imaging
资金
- Indian Council of Medical Research [7/1/12/2018-RMC]
The study discusses the correlation between bulk tissue polarimetry images and histopathology in soft tissues, presenting the potential of bulk tissue Mueller polarimetry and image analysis as an alternative to tissue histopathology.
Polarimetric imaging and image analysis have gained increased interest in soft tissue analysis at the cellular level. However, polarimetric imaging has widely been tested on thin tissue sections to provide reliable information correlated with histopathological findings. Polarimetric bulk tissue analysis always offered an overall assessment of various tissue optical properties for diagnosis. In this study, the histopathological correlation of bulk tissue polarimetry images for soft tissues is discussed. The first-hand information on the use of bulk tissue Mueller polarimetry and image analysis as an alternative to tissue histopathology is presented for surgically extracted colon and breast tissues.
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