期刊
JOURNAL OF ADOLESCENT HEALTH
卷 69, 期 2, 页码 346-348出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jadohealth.2020.12.134
关键词
HIV; Alcohol use; Biomarker; Youth; Feasibility; ATN; EtG; Ethyl glucuronide; TLFB; ASSIST
资金
- National Institute of Mental Health, National Institute on Drug Abuse
- Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health [K01MH116737, K01AA024500, R01AA022891, U19HD089875]
This study assessed the feasibility of using the ethyl glucuronide biomarker from nail sampling to measure alcohol use among youth living with HIV in the United States, and found correlations between the EtG biomarker and self-reported measures of alcohol use.
Purpose: We assessed the feasibility of the ethyl glucuronide biomarker (EtG) through nail sampling to measure alcohol use among youth living with HIV in the United States (YLWH, N = 183); we also evaluated concordance between this EtG biomarker and self-reported measures of alcohol use, specifically, the Alcohol Timeline Followback (TFLB) and Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST). Methods: EtG, TFLB, and ASSIST were collected at 4 points over 1 year. At baseline and 52 weeks, 78.1% and 70.1%, respectively, provided a valid (full or partial) sample. Results: At 16 weeks, EtG was associated with ASSIST (r = .25, p < .05). At 28 weeks and 52 weeks, TFLB and ASSIST were correlated with EtG (at 28 weeks r = .23, p < .05 and r = .41, p < .01, respectively; at 52 weeks r = .34, p < .01 and r = .25, p < .05, respectively). Conclusions: We found that nail-based EtG biomarker was feasible to measure alcohol use among YLWH; we also found concordance between EtG, TLFB, and ASSIST, supporting ongoing use of self reported alcohol use measures with YLWH. (c) 2021 Society for Adolescent Health and Medicine. All rights reserved.
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