Immortal Time Bias in Observational Studies

This JAMA Guide to Statistics and Medicine explains immortal time bias, an error in estimating the association between an exposure and an outcome that results from misclassification or exclusion of time intervals; explains how this misclassification or exclusion can occur; and presents approaches to minimize or avoid immortal time bias.

Automated summary

This article explains immortal time bias, which is an error that can occur when estimating the association between exposure and outcome, and presents approaches to minimize or avoid this bias.