相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Nanotechnology to improve the Alzheimer's disease therapy with natural compounds
Maria Joao Ramalho et al.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2020)
Cerebral amyloid angiopathy and Alzheimer disease - one peptide, two pathways
Steven M. Greenberg et al.
NATURE REVIEWS NEUROLOGY (2020)
(-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse model
Yinyin Wu et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020)
Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease
Raymond S. Turner et al.
ANNALS OF NEUROLOGY (2020)
Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice
Helen Crehan et al.
ALZHEIMERS RESEARCH & THERAPY (2020)
Preclinical and clinical studies on bryostatins, a class of marine-derived protein kinase C modulators: A mini-review
Rinky Raghuvanshi et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2020)
Understanding the Pathophysiology of Cerebral Amyloid Angiopathy
Laura Gatti et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep
Sara Marie Ulv Larsen et al.
PLOS BIOLOGY (2020)
Neurovascular Unit Dysfunction and Neurodegenerative Disorders
Xing Yu et al.
FRONTIERS IN NEUROSCIENCE (2020)
Interactions between Amyloid-B Proteins and Human Brain Pericytes: Implications for the Pathobiology of Alzheimer's Disease
Donald J. Alcendor
JOURNAL OF CLINICAL MEDICINE (2020)
Glymphatic failure as a final common pathway to dementia
Maiken Nedergaard et al.
SCIENCE (2020)
Current and Future Treatments in Alzheimer Disease: An Update
Konstantina G. Yiannopoulou et al.
JOURNAL OF CENTRAL NERVOUS SYSTEM DISEASE (2020)
Drug Development for Alzheimer's Disease: Microglia Induced Neuroinflammation as a Target?
Yuan Dong et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Innovative Therapy for Alzheimer's Disease-With Focus on Biodelivery of NGF
Sumonto Mitra et al.
FRONTIERS IN NEUROSCIENCE (2019)
Anakinra Therapy for Non-cancer Inflammatory Diseases (vol 9, 1157, 2018)
Giulio Cavalli et al.
FRONTIERS IN PHARMACOLOGY (2019)
Target engagement in an alzheimer trial: Crenezumab lowers amyloid β oligomers in cerebrospinal fluid
Ting Yang et al.
ANNALS OF NEUROLOGY (2019)
Effect of Different Classes of Antihypertensive Drugs on Endothelial Function and Inflammation
Isabella Viana Gomes Silva et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Interaction of natural compounds with biomembrane models: A biophysical approach for the Alzheimer's disease therapy
Stephanie Andrade et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2019)
Complement Receptor 1 (CR1, CD35) Polymorphisms and Soluble CR1: A Proposed Anti-inflammatory Role to Quench the Fire of Fogo Selvagem Pemphigus Foliaceus
Luana Caroline Oliveira et al.
FRONTIERS IN IMMUNOLOGY (2019)
Pharmacokinetics and Pharmacodynamics of the BACE1 Inhibitor Verubecestat (MK-8931) in Healthy Japanese Adults: A Randomized, Placebo-Controlled Study
K. Chris Min et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2019)
Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice
Takashi Mori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Advances in cerebral amyloid angiopathy imaging
Szu-Ju Chen et al.
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2019)
The TOMMORROW study: Design of an Alzheimer's disease delay-of-onset clinical trial
Daniel K. Burns et al.
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS (2019)
VEGFR1 and VEGFR2 in Alzheimer's Disease
Rachel Harris et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
An Overview on the Clinical Development of Tau-Based Therapeutics
Miguel Medina
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Memantine for the Treatment of Dementia: A Review on its Current and Future Applications
Jaume Folch et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Role of Blood-Brain Barrier in Alzheimer's Disease
Zhiyou Cai et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
The A beta protofibril selective antibody mAb158 prevents accumulation of A beta in astrocytes and rescues neurons from A beta-induced cell death
Sofia Sollvander et al.
JOURNAL OF NEUROINFLAMMATION (2018)
Tau-targeting therapies for Alzheimer disease
Erin E. Congdon et al.
NATURE REVIEWS NEUROLOGY (2018)
Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
Melanie D. Sweeney et al.
NATURE REVIEWS NEUROLOGY (2018)
Review of the advances in treatment for Alzheimer disease: Strategies for combating beta-amyloid protein
J. Folch et al.
NEUROLOGIA (2018)
TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
Yingjun Zhao et al.
NEURON (2018)
Microglial Activation Is Modulated by Captopril: in Vitro and in Vivo Studies
Keren Asraf et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link
Jaime Ramos-Cejudo et al.
EBIOMEDICINE (2018)
Anti-α4β1 Integrin Antibodies Attenuated Brain Inflammatory Changes in a Mouse Model of Alzheimer's Disease
Gunjan Manocha et al.
CURRENT ALZHEIMER RESEARCH (2018)
Neurovascular dysfunction in vascular dementia, Alzheimer's and atherosclerosis
Osman Shabir et al.
BMC NEUROSCIENCE (2018)
Liposome delivery systems for the treatment of Alzheimer's disease
Callum Ross et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)
The glymphatic pathway in neurological disorders
Martin Kaag Rasmussen et al.
LANCET NEUROLOGY (2018)
Complement protein C5a enhances the β-amyloid-induced neuro-inflammatory response in microglia in Alzheimer's disease
Xiao-qun An et al.
M S-MEDECINE SCIENCES (2018)
Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism
Qingyi Ma et al.
MOLECULAR NEURODEGENERATION (2018)
Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection
Bapurao Surnar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
SAR228810: an antibody for protofibrillar amyloid peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA)
Laurent Pradier et al.
ALZHEIMERS RESEARCH & THERAPY (2018)
Glucagon like peptide-1 (GLP-1) likes Alzheimer's disease
Ilgin Yildirim Simsir et al.
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2018)
Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer's Disease
Yu Yamazaki et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Neurotoxic reactive astrocytes are induced by activated microglia
Shane A. Liddelow et al.
NATURE (2017)
A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging
Eyiyemisi C. Damisah et al.
NATURE NEUROSCIENCE (2017)
Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
Kassandra Kisler et al.
NATURE REVIEWS NEUROSCIENCE (2017)
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
Costantino Iadecola
NEURON (2017)
Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer's disease
Nophar Geifman et al.
ALZHEIMERS RESEARCH & THERAPY (2017)
Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains
Douglas M. Zeppenfeld et al.
JAMA NEUROLOGY (2017)
The Pathophysiological Role of Microglia in Dynamic Surveillance, Phagocytosis and Structural Remodeling of the Developing CNS
Cataldo Arcuri et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Tauopathies - Focus on Changes at the Neurovascular Unit
Alena Michalicova et al.
CURRENT ALZHEIMER RESEARCH (2017)
Roles of tau protein in health and disease
Tong Guo et al.
ACTA NEUROPATHOLOGICA (2017)
Ion channel networks in the control of cerebral blood flow
Thomas A. Longden et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2016)
The role of insulin in the vascular contributions to age-related dementia
Timothy M. Hughes et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
Amy R. Nelson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases
Erik N. T. P. Bakker et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2016)
Two Phase 2 Multiple Ascending-Dose Studies of Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Mild-to-Moderate Alzheimer's Disease
Florence Pasquier et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Drug delivery of the future: Chasing the invisible gorilla
Kinam Park
JOURNAL OF CONTROLLED RELEASE (2016)
Nanoparticle-mediated brain drug delivery: Overcoming blood-brain barrier to treat neurodegenerative diseases
Claudia Saraiva et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Neuroinflammation: the devil is in the details
Damon J. DiSabato et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Memantine mediates neuroprotection via regulating neurovascular unit in a mouse model of focal cerebral ischemia
Zheng-Zhen Chen et al.
LIFE SCIENCES (2016)
Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke
Xiao-Yi Xiong et al.
PROGRESS IN NEUROBIOLOGY (2016)
Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure
Feng Xu et al.
NATURE COMMUNICATIONS (2016)
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models
Michael J. D. Daniels et al.
NATURE COMMUNICATIONS (2016)
Current Research Therapeutic Strategies for Alzheimer's Disease Treatment
Jaume Folch et al.
NEURAL PLASTICITY (2016)
Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function
Maria I. Fonseca et al.
PLOS ONE (2016)
Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models
Valeria Melisa et al.
BEHAVIOURAL PHARMACOLOGY (2015)
Establishment and Dysfunction of the Blood-Brain Barrier
Zhen Zhao et al.
CELL (2015)
Dexamethasone potentiates in vitro blood-brain barrier recovery after primary blast injury by glucocorticoid receptor-mediated upregulation of ZO-1 tight junction protein
Christopher D. Hue et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)
Tonic Local Brain Blood Flow Control by Astrocytes Independent of Phasic Neurovascular Coupling
David G. Rosenegger et al.
JOURNAL OF NEUROSCIENCE (2015)
Neuroinflammation in Alzheimer's disease
Michael T. Heneka et al.
LANCET NEUROLOGY (2015)
Clearance systems in the brain-implications for Alzheimer disease
Jenna M. Tarasoff-Conway et al.
NATURE REVIEWS NEUROLOGY (2015)
The Glymphatic System: A Beginner's Guide
Nadia Aalling Jessen et al.
NEUROCHEMICAL RESEARCH (2015)
Cerebral Hypoperfusion-Assisted Intra-arterial Deposition of Liposomes in Normal and Glioma-Bearing Rats
Shailendra Joshi et al.
NEUROSURGERY (2015)
The Blood-Brain Barrier
Richard Daneman et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
Targeting Prodromal Alzheimer Disease With Avagacestat A Randomized Clinical Trial
Vladimir Coric et al.
JAMA NEUROLOGY (2015)
The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease
Josiane Budni et al.
AGING AND DISEASE (2015)
Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy
Laura J. Blair et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
First Administration of the Fc-Attenuated Anti-β Amyloid Antibody GSK933776 to Patients with Mild Alzheimer's Disease: A Randomized, Placebo-Controlled Study
Niels Andreasen et al.
PLOS ONE (2015)
Anti-Inflammatory Drugs and Risk of Alzheimer's Disease: An Updated Systematic Review and Meta-Analysis
Jun Wang et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Vasculoprotection as a Convergent, Multi-Targeted Mechanism of Anti-AD Therapeutics and Interventions
Narayan R. Bhat
JOURNAL OF ALZHEIMERS DISEASE (2015)
Lenti-GDNF Gene Therapy Protects Against Alzheimer's Disease-Like Neuropathology in 3xTg-AD Mice and MC65 Cells
Susana Revilla et al.
CNS NEUROSCIENCE & THERAPEUTICS (2014)
Pial arteries respond earlier than penetrating arterioles to neural activation in the somatosensory cortex in awake mice exposed to chronic hypoxia: an additional mechanism to proximal integration signaling?
Yuta Sekiguchi et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2014)
Age-Dependent, Non-Cell-Autonomous Deposition of Amyloid from Synthesis of β-Amyloid by Cells Other Than Excitatory Neurons
Karthikeyan Veeraraghavalu et al.
JOURNAL OF NEUROSCIENCE (2014)
Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer's disease model
Brice Ongali et al.
NEUROBIOLOGY OF DISEASE (2014)
First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model
Eva Kontsekova et al.
ALZHEIMERS RESEARCH & THERAPY (2014)
BACE1 inhibitor drugs in clinical trials for Alzheimer's disease
Robert Vassar
ALZHEIMERS RESEARCH & THERAPY (2014)
Alzheimer's disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs
Juan M. Zolezzi et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
Insulin as a bridge between type 2 diabetes and Alzheimer disease - how anti-diabetics could be a solution for dementia
Ines Sebastiao et al.
FRONTIERS IN ENDOCRINOLOGY (2014)
γ-Secretase inhibitors and modulators
Todd E. Golde et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia
Xin Liu et al.
BIOMATERIALS (2013)
The effect of cationic albumin-conjugated PEGylated tanshinone IIA nanoparticles on neuronal signal pathways and neuroprotection in cerebral ischemia
Xin Liu et al.
BIOMATERIALS (2013)
Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice
Sandra Sivilia et al.
BMC NEUROSCIENCE (2013)
Calcium channel blockers and dementia
V. Nimmrich et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Vascular Risk Factors and Neurodegeneration in Ageing Related Dementias: Alzheimer’s Disease and Vascular Dementia
Rufus Akinyemi et al.
Current Alzheimer Research (2013)
On the Interaction of β-Amyloid Peptides and α7-Nicotinic Acetylcholine Receptors in Alzheimer’s Disease
Murat Oz et al.
Current Alzheimer Research (2013)
Neurovascular Defects and Faulty Amyloid-beta Vascular Clearance in Alzheimer's Disease
Abhay P. Sagare et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Modulation of alpha 7 Nicotinic Acetylcholine Receptor and Fibrillar Amyloid-beta Interactions in Alzheimer's Disease Brain
Ruiqing Ni et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Layer-specific dilation of penetrating arteries induced by stimulation of the nucleus basalis of Meynert in the mouse frontal cortex
Harumi Hotta et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2013)
Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease
Michelle A. Erickson et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2013)
Intravenous immunoglobulin and Alzheimer's disease: what now?
David A. Loeffler
JOURNAL OF NEUROINFLAMMATION (2013)
Immunotherapy for Alzheimer's disease: hoops and hurdles
Cynthia A. Lemere
MOLECULAR NEURODEGENERATION (2013)
CLAUDINS AND THE MODULATION OF TIGHT JUNCTION PERMEABILITY
Dorothee Guenzel et al.
PHYSIOLOGICAL REVIEWS (2013)
Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer's Disease with Combined Amyloid-beta and Cerebrovascular Pathology
Panayiota Papadopoulos et al.
PLOS ONE (2013)
VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival
Piotr Religa et al.
SCIENTIFIC REPORTS (2013)
Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain
Vinita Rangroo Thrane et al.
SCIENTIFIC REPORTS (2013)
Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment A Pilot Clinical Trial
Suzanne Craft et al.
ARCHIVES OF NEUROLOGY (2012)
Angiotensin II AT1 receptor blockers as treatments for inflammatory brain disorders
Juan M. Saavedra
CLINICAL SCIENCE (2012)
Fatty acids acutely enhance insulin-induced oxidative stress and cause insulin resistance by increasing mitochondrial reactive oxygen species (ROS) generation and nuclear factor-κB inhibitor (IκB)-nuclear factor-κB (NFκB) activation in rat muscle, in the absence of mitochondrial dysfunction
R. Barazzoni et al.
DIABETOLOGIA (2012)
Overview and introduction: The blood-brain barrier in health and disease
N. Joan Abbott et al.
EPILEPSIA (2012)
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia
Hongjun Fu et al.
GLIA (2012)
Brain Pericytes ABCA1 Expression Mediates Cholesterol Efflux but not Cellular Amyloid-β Peptide Accumulation
Julien Saint-Pol et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease
Rashid Deane et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Age-Dependent Rescue by Simvastatin of Alzheimer's Disease Cerebrovascular and Memory Deficits
Xin-Kang Tong et al.
JOURNAL OF NEUROSCIENCE (2012)
Genomic Analysis of Reactive Astrogliosis
Jennifer L. Zamanian et al.
JOURNAL OF NEUROSCIENCE (2012)
The many faces of insulin-like peptide signalling in the brain
Ana M. Fernandez et al.
NATURE REVIEWS NEUROSCIENCE (2012)
Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy
Anna Carrano et al.
NEURODEGENERATIVE DISEASES (2012)
Morphological and Pathological Evolution of the Brain Microcirculation in Aging and Alzheimer's Disease
Jesse M. Hunter et al.
PLOS ONE (2012)
Neurovascular Dysfunction and Faulty Amyloid β-Peptide Clearance in Alzheimer Disease
Abhay P. Sagare et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
PF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease
Marwan N. Sabbagh et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2011)
Rosiglitazone and Pioglitazone for the Treatment of Alzheimer's Disease
Benjamin W. Miller et al.
ANNALS OF PHARMACOTHERAPY (2011)
Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: The case for isradipine
Thimmappa S. Anekonda et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Solanezumab for Alzheimer's disease
Hossein Samadi et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2011)
Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
Allal Boutajangout et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity
Dan Zhang et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease
Paula Grammas
JOURNAL OF NEUROINFLAMMATION (2011)
Central nervous system pericytes in health and disease
Ethan A. Winkler et al.
NATURE NEUROSCIENCE (2011)
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
Berislav V. Zlokovic
NATURE REVIEWS NEUROSCIENCE (2011)
Mechanism mediating oligomeric Aβ clearance by naive primary microglia
Cheng-Ning Yang et al.
NEUROBIOLOGY OF DISEASE (2011)
Sporadic cerebral amyloid angiopathy
J. Attems et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2011)
Targeting the neurovascular unit for treatment of neurological disorders
Reyna L. VanGilder et al.
PHARMACOLOGY & THERAPEUTICS (2011)
HI 6 human serum albumin nanoparticles-Development and transport over an in vitro blood-brain barrier model
Miriam Dadparvar et al.
TOXICOLOGY LETTERS (2011)
Hereditary Cerebral Hemorrhage With Amyloidosis Associated With the E693K Mutation of APP
Orso Bugiani et al.
ARCHIVES OF NEUROLOGY (2010)
ABC efflux transporters in brain vasculature of Alzheimer's subjects
Hasini C. Wijesuriya et al.
BRAIN RESEARCH (2010)
Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein
Ruben J. Boado et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease
Rahasson R. Ager et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Evidence of Carrier-Mediated Transport in the Penetration of Donepezil into the Rat Brain
Mi-Hwa Kim et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2010)
Glial and neuronal control of brain blood flow
David Attwell et al.
NATURE (2010)
Pericytes regulate the blood-brain barrier
Annika Armulik et al.
NATURE (2010)
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
Cameron R. Stewart et al.
NATURE IMMUNOLOGY (2010)
Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
Robert D. Bell et al.
NEURON (2010)
Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
Robert D. Bell et al.
ACTA NEUROPATHOLOGICA (2009)
Contribution of hypoxia to Alzheimer's disease: is HIF-1α a mediator of neurodegeneration?
O. O. Ogunshola et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Immunotherapy, Vascular Pathology, and Microhemorrhages in Transgenic Mice
Donna M. Wilcock et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2009)
Development of semagacestat (LY450139), a functional γ-secretase inhibitor, for the treatment of Alzheimer's disease
David B. Henley et al.
EXPERT OPINION ON PHARMACOTHERAPY (2009)
A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia
Christine L. Hsieh et al.
JOURNAL OF NEUROCHEMISTRY (2009)
CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar Aβ-Stimulated Microglial Activation
Erin G. Reed-Geaghan et al.
JOURNAL OF NEUROSCIENCE (2009)
A Nanomedicine Transports a Peptide Caspase-3 Inhibitor across the Blood-Brain Barrier and Provides Neuroprotection
Hulya Karatas et al.
JOURNAL OF NEUROSCIENCE (2009)
Matrix metalloproteinases and their multiple roles in neurodegenerative diseases
Gary A. Rosenberg
LANCET NEUROLOGY (2009)
NEUROSCIENCE Alzheimer's disease
Lennart Mucke
NATURE (2009)
SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells
Robert D. Bell et al.
NATURE CELL BIOLOGY (2009)
Risk of dementia and AD with prior exposure to NSAIDs in an elderly community-based cohort
J. C. S. Breitner et al.
NEUROLOGY (2009)
Targeting Extracellular Matrix Proteolysis for Hemorrhagic Complications of tPA Stroke Therapy
Xiaoying Wang et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2008)
Amyloid beta oligomers induce impairment of neuronal insulin receptors
Wei-Qin Zhao et al.
FASEB JOURNAL (2008)
The role of adherens junctions and VE-cadherin in the control of vascular permeability
Elisabetta Dejana et al.
JOURNAL OF CELL SCIENCE (2008)
Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor γ agonist
Nektaria Nicolakakis et al.
JOURNAL OF NEUROSCIENCE (2008)
The blood-brain barrier in health and chronic neurodegenerative disorders
Berislav V. Zlokovic
NEURON (2008)
Natalizumab: Targeting alpha(4)-integrins in multiple sclerosis
Britta Engelhardt et al.
NEURODEGENERATIVE DISEASES (2008)
Lipoprotein receptor-related protein-1 mediates amyloid-β-mediated cell death of cerebrovascular cells
Micha M. M. Wilhelmus et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Bahareh Ajami et al.
NATURE NEUROSCIENCE (2007)
Acetylcholinesterase inhibitors, neuropsychiatric symptoms, and Alzheimer's disease subtypes: An alternate hypothesis to global cognitive enhancement
Geri Brousseau et al.
EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY (2007)
MDR1-P-glycoprotein (ABCB1) mediates transport of Alzheimer's amyloid-β peptides -: Implications for the mechanisms of Aβ clearance at the blood-brain barrier
Diana Kuhnke et al.
BRAIN PATHOLOGY (2007)
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements
Ayodeji A. Asuni et al.
JOURNAL OF NEUROSCIENCE (2007)
The blood-brain barrier and cancer:: Transporters, treatment, and Trojan horses
John F. Deeken et al.
CLINICAL CANCER RESEARCH (2007)
Blood-brain barrier delivery
William M. Pardridge
DRUG DISCOVERY TODAY (2007)
Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; Importance for CNS drug discovery and development
Sumio Ohtsuki et al.
PHARMACEUTICAL RESEARCH (2007)
Brain cancer diagnosis and therapy with nanoplatforms
Yong-Eun Lee Koo et al.
ADVANCED DRUG DELIVERY REVIEWS (2006)
Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases
Eugenio Cersosimo et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2006)
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment
Stephen W. Scheff et al.
NEUROBIOLOGY OF AGING (2006)
Molecular Trojan horses for blood-brain barrier drug delivery
William M. Pardridge
CURRENT OPINION IN PHARMACOLOGY (2006)
RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease
John E. Donahue et al.
ACTA NEUROPATHOLOGICA (2006)
Perivascular nerves and the regulation of cerebrovascular tone
E Hamel
JOURNAL OF APPLIED PHYSIOLOGY (2006)
Hereditary cerebral hemorrhage with amyloidosis-Dutch type
M Maat-Schieman et al.
NEUROPATHOLOGY (2005)
The blood-brain barrier/neurovascular unit in health and disease
BT Hawkins et al.
PHARMACOLOGICAL REVIEWS (2005)
Clinical effects of Aβ immunization (AN1792) in patients with AD in an interrupted trial
S Gilman et al.
NEUROLOGY (2005)
Effects of a behaviorally active antibody on the brain uptake and clearance of amyloid beta proteins
WA Banks et al.
PEPTIDES (2005)
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
ZH Wu et al.
NATURE MEDICINE (2005)
Neurovascular regulation in the normal brain and in Alzheimer's disease
C Iadecola
NATURE REVIEWS NEUROSCIENCE (2004)
Endothelial cell-to-cell junctions: Molecular organization and role in vascular homeostasis
G Bazzoni et al.
PHYSIOLOGICAL REVIEWS (2004)
Are the extracelluar pathways a conduit for the delivery of therapeutics to the brain?
WA Banks
CURRENT PHARMACEUTICAL DESIGN (2004)
Glial reactions and the clearance of amyloid β protein in the brains of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type
MLC Maat-Schieman et al.
ACTA NEUROPATHOLOGICA (2004)
RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain
R Deane et al.
NATURE MEDICINE (2003)
A CD36-initiated signaling cascade mediates inflammatory effects of β-amyloid
KJ Moore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Passage of amyloid β protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease
WA Banks et al.
PEPTIDES (2002)
Neuroscience - New insights into neuron-glia communication
RD Fields et al.
SCIENCE (2002)
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease:: A 26-week randomized, placebo-controlled, double-blind trial
M Simons et al.
ANNALS OF NEUROLOGY (2002)
Astrocyte-endothelial interactions and blood-brain barrier permeability
NJ Abbott
JOURNAL OF ANATOMY (2002)
Alzheimer's β-amyloid peptides compete for insulin binding to the insulin receptor -: art. no. RC221
L Xie et al.
JOURNAL OF NEUROSCIENCE (2002)
Expression of the neonatal Fc receptor (FcRn) at the blood-brain barrier
F Schlachetzki et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Astrocytes function in matching blood flow to metabolic activity
DR Harder et al.
NEWS IN PHYSIOLOGICAL SCIENCES (2002)
Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
RB DeMattos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Amyloid β protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain
Y Harigaya et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Age-related plaque morphology and C-terminal heterogeneity of amyloid β in Dutch-type hereditary cerebral hemorrhage with amyloidosis
MLC Maat-Schieman et al.
ACTA NEUROPATHOLOGICA (2000)