相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。CIM6P/IGF-2 Receptor Ligands Reverse Deficits in Angelman Syndrome Model Mice
Emmanuel Cruz et al.
AUTISM RESEARCH (2021)
The role of long non-coding RNA H19 in breast cancer (Review)
Ji Wang et al.
ONCOLOGY LETTERS (2020)
Insulin-like growth factor-II and bioactive proteins containing a part of the E-domain of pro-insulin-like growth factor-II
Jaap van Doorn
BIOFACTORS (2020)
Multiple Growth Factor Targeting by Engineered Insulin-like Growth Factor Binding Protein-3 Augments EGF Receptor Tyrosine Kinase Inhibitor Efficacy
Elizabeth A. Wang et al.
SCIENTIFIC REPORTS (2020)
RSRCI loss-of-function variants cause mild to moderate autosomal recessive intellectual disability
Marcello Scala et al.
BRAIN (2020)
Altered insulin-like growth factor-2 signaling is associated with psychopathology and cognitive deficits in patients with schizophrenia
Yuan-Jian Yang et al.
PLOS ONE (2020)
A role for CIM6P/IGF2 receptor in memory consolidation and enhancement
Xiao-Wen Yu et al.
ELIFE (2020)
Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates
Paula Garcia-Huerta et al.
ACTA NEUROPATHOLOGICA (2020)
Insulin-Like Growth Factor 2 (IGF-2) Regulates Neuronal Density and IGF-2 Distribution Following Hippocampal Intracerebral Hemorrhage
Farzaneh Vafaee et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2020)
Isoform- and Paralog-Switching in IR-Signaling: When Diabetes Opens the Gates to Cancer
Pierluigi Scalia et al.
BIOMOLECULES (2020)
The Capability to Learn and Expression of the Insulin-Like Growth Factor II Gene in the Brain of Male Rats Whose Fathers Were Subjected to Stress Factors in the Stress-Restress Paradigm
N. E. Ordyan et al.
NEUROCHEMICAL JOURNAL (2020)
Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior
Marion Soto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Cholinergic Deficit Induced by Central Administration of 192IgG-Saporin Is Associated With Activation of Microglia and Cell Loss in the Dorsal Hippocampus of Rats
Yulia Dobryakova et al.
FRONTIERS IN NEUROSCIENCE (2019)
The insulin-like growth factor 2 gene in mammals: Organizational complexity within a conserved locus
Kabita Baral et al.
PLOS ONE (2019)
Density distribution of gene expression profiles and evaluation of using maximal information coefficient to identify differentially expressed genes
Han-Ming Liu et al.
PLOS ONE (2019)
Cognition may link cortical IGFBP5 levels with motor function in older adults
Aron S. Buchman et al.
PLOS ONE (2019)
Circulating IGFBP-2: a novel biomarker for incident dementia
Emer R. McGrath et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2019)
IGFBP2 Plays an Essential Role in Cognitive Development during Early Life
Shumsuzzaman Khan et al.
ADVANCED SCIENCE (2019)
IGFBP-2 Signaling in the Brain: From Brain Development to Higher Order Brain Functions
Shumsuzzaman Khan
FRONTIERS IN ENDOCRINOLOGY (2019)
The Neglected Insulin: IGF-II, a Metabolic Regulator with Implications for Diabetes, Obesity, and Cancer
Jeff M. P. Holly et al.
CELLS (2019)
IR-A/IGF-1R-mediated signals promote epithelial-mesenchymal transition of endometrial carcinoma cells by activating PI3K/AKT and ERK pathways
Chunfang Wang et al.
CANCER BIOLOGY & THERAPY (2019)
Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons
Jean-Michel Cioni et al.
CELL (2019)
Insulin growth factor 2 (IGF2) as an emergent target in psychiatric and neurological disorders. Review
M. Pardo et al.
NEUROSCIENCE RESEARCH (2019)
Combined Fluoxetine and Metformin Treatment Potentiates Antidepressant Efficacy Increasing IGF2 Expression in the Dorsal Hippocampus
Silvia Poggini et al.
NEURAL PLASTICITY (2019)
The Role of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Nervous System
Moira S. Lewitt et al.
BIOCHEMISTRY INSIGHTS (2019)
Insulin-Like Growth Factor II Targets the mTOR Pathway to Reverse Autism-Like Phenotypes in Mice
Adam B. Steinmetz et al.
JOURNAL OF NEUROSCIENCE (2018)
Retromer and the cation-independent mannose 6-phosphate receptor-Time for a trial separation?
Matthew N. J. Seaman
TRAFFIC (2018)
Oncogenic activity of insulin in the development of non-small cell lung carcinoma
Jie Jiang et al.
ONCOLOGY LETTERS (2018)
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia
Lei Yu et al.
ANNALS OF NEUROLOGY (2018)
RSRC1 mutation affects intellect and behaviour through aberrant splicing and transcription, downregulating IGFBP3
Yonatan Perez et al.
BRAIN (2018)
Genome-scale identification of cellular pathways required for cell surface recognition
Sumana Sharma et al.
GENOME RESEARCH (2018)
Insulin-Like Growth Factor (IGF) System in Liver Diseases
Agnieszka Adamek et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
The complex genetics of human insulin-like growth factor 2 are not reflected in public databases
Peter Rotwein
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons
Xiu-Tang Cheng et al.
JOURNAL OF CELL BIOLOGY (2018)
Imbalanced Expression of IGF2 and PCSK4 Is Associated With Overproduction of Big IGF2 in SFT With NICTH: A Pilot Study
Shintaro Kawai et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease
Sara Mostafavi et al.
NATURE NEUROSCIENCE (2018)
Atlas of tissue- and developmental stage specific gene expression for the bovine insulin-like growth factor (IGF) system
Mani Ghanipoor-Samami et al.
PLOS ONE (2018)
Identification of Insulin Receptor Splice Variant B in Neurons by in situ Detection in Human Brain Samples
Brian Spencer et al.
SCIENTIFIC REPORTS (2018)
The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells
Junguo Cao et al.
STEM CELLS INTERNATIONAL (2018)
Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer's Disease Pathology and Shows Differential Expression in Transgenic Mice
Luke W. Bonham et al.
FRONTIERS IN NEUROSCIENCE (2018)
Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
Sreemathi Logan et al.
MOLECULAR METABOLISM (2018)
IGF-Binding Proteins: Why Do They Exist and Why Are There So Many?
John B. Allard et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain
Arpiar Saunders et al.
CELL (2018)
Biosynthesis, structure, and folding of the insulin precursor protein
Ming Liu et al.
DIABETES OBESITY & METABOLISM (2018)
Comparative transcriptomics of choroid plexus in Alzheimer's disease, frontotemporal dementia and Huntington's disease: implications for CSF homeostasis
Edward G. Stopa et al.
FLUIDS AND BARRIERS OF THE CNS (2018)
Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I
Ana M. Fernandez et al.
DIABETES (2017)
Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases
Y. Wang et al.
MOLECULAR NEUROBIOLOGY (2017)
Insulin Receptor Isoforms in Physiology and Disease: An Updated View
Antonino Belfiore et al.
ENDOCRINE REVIEWS (2017)
Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer's disease neurons
Prasad Tammineni et al.
HUMAN MOLECULAR GENETICS (2017)
Unravelling novel functions of the endosomal transporter mannose 6-phosphate/insulin-like growth factor receptor (CD222) in health and disease: An emerging regulator of the immune system
Vladimir Leksa et al.
IMMUNOLOGY LETTERS (2017)
Activity-dependent trafficking of lysosomes in dendrites and dendritic spines
Marisa S. Goo et al.
JOURNAL OF CELL BIOLOGY (2017)
Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR
Boris Simonetti et al.
JOURNAL OF CELL BIOLOGY (2017)
Activity-Dependent Exocytosis of Lysosomes Regulates the Structural Plasticity of Dendritic Spines
Zahid Padamsey et al.
NEURON (2017)
IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718
Mie Andersen et al.
PLOS ONE (2017)
IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids
E. Martin-Montanez et al.
REDOX BIOLOGY (2017)
Long days enhance recognition memory and increase insulin-like growth factor 2 in the hippocampus
Adriano Dellapolla et al.
SCIENTIFIC REPORTS (2017)
3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders
Chun-Ting Lee et al.
JOURNAL OF BIOMEDICAL SCIENCE (2017)
Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice
Marta Pardo et al.
JCI INSIGHT (2017)
Insulin-Like Growth Factor Binding Protein-3 Deficiency Leads to Behavior Impairment with Monoaminergic and Synaptic Dysfunction
Hongmei Dai et al.
AMERICAN JOURNAL OF PATHOLOGY (2017)
Engineering growth factors for regenerative medicine applications
Aaron C. Mitchell et al.
ACTA BIOMATERIALIA (2016)
Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability
Cristina Garcia-Caceres et al.
CELL (2016)
Signal processing by the endosomal system
Roberto Villasenor et al.
CURRENT OPINION IN CELL BIOLOGY (2016)
The Insulin-Like Growth Factor I Receptor Regulates Glucose Transport by Astrocytes
Edwin Hernandez-Garzon et al.
GLIA (2016)
Insulin-like growth factor 2 rescues aging-related memory loss in rats
Adam B. Steinmetz et al.
NEUROBIOLOGY OF AGING (2016)
IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses
Neta Gazit et al.
NEURON (2016)
Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease
Carmela Matrone et al.
PLOS ONE (2016)
Spatiotemporal Resolution of Rab9 and CI-MPR Dynamics in the Endocytic Pathway
Ana Kucera et al.
TRAFFIC (2016)
Long-Term Estrogen Receptor Beta Agonist Treatment Modifies the Hippocampal Transcriptome in Middle-Aged Ovariectomized Rats
Miklos Sarvari et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS
Ilary Allodi et al.
SCIENTIFIC REPORTS (2016)
Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain
Akiko Terauchi et al.
ELIFE (2016)
Hipposeq: a comprehensive RNA-seq database of gene expression in hippocampal principal neurons
Mark S. Cembrowski et al.
ELIFE (2016)
IGF1R levels in the brain negatively correlate with longevity in 16 rodent species
Jorge Azpurua et al.
Aging-US (2016)
Overexpression of SIRT6 in the hippocampal CA1 impairs the formation of long-term contextual fear memory
Xi Yin et al.
SCIENTIFIC REPORTS (2016)
IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb
Kimberley C. W. Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2015)
From One-Cell to Tissue: Reprogramming, Cell Differentiation and Tissue Engineering
Donghui Zhang et al.
BIOSCIENCE (2015)
Exogenous insulin-like growth factor 2 administration enhances memory consolidation and persistence in a time-dependent manner
Younghwan Lee et al.
BRAIN RESEARCH (2015)
Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity
Claudia A. Grillo et al.
DIABETES (2015)
Nuclear actions of insulin-like growth factor binding protein-3
Robert C. Baxter
GENE (2015)
The landscape of genomic imprinting across diverse adult human tissues
Yael Baran et al.
GENOME RESEARCH (2015)
Identification of a fourth mannose 6-phosphate binding site in the cation-independent mannose 6-phosphate receptor
Linda J. Olson et al.
GLYCOBIOLOGY (2015)
Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability
Y. Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay
Wendy E. Heywood et al.
MOLECULAR NEURODEGENERATION (2015)
Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and-2 caused by elevated Igf2 signaling in the cortex
Ali Shahmoradi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis
S. R. Ferron et al.
NATURE COMMUNICATIONS (2015)
Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors
Claire J. Garwood et al.
MOLECULAR BRAIN (2015)
The Regulatory Mechanism of Neurogenesis by IGF-1 in Adult Mice
Honghua Yuan et al.
MOLECULAR NEUROBIOLOGY (2015)
Insulin Like Growth Factor 2 Expression in the Rat Brain Both in Basal Condition and following Learning Predominantly Derives from the Maternal Allele
Xiaojing Ye et al.
PLOS ONE (2015)
Increased Cerebrospinal Fluid Level of Insulin-like Growth Factor-II in Male Patients with Alzheimer's Disease
Daniel Aberg et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Involvement of IGF-II receptors in the antioxidant and neuroprotective effects of IGF-II on adult cortical neuronal cultures
Elisa Martin-Montanez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Changes in cerebrospinal fluid and blood plasma levels of IGF-II and its binding proteins in Alzheimer's disease: an observational study
Joakim Hertze et al.
BMC NEUROLOGY (2014)
Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice
Maria Pascual-Lucas et al.
EMBO MOLECULAR MEDICINE (2014)
Insulin and insulin-like growth factor receptors in the brain: Physiological and pathological aspects
Haim Werner et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2014)
Column chromatographic characterization of complex formation of pro-IGF-II isoforms with acid labile subunit and IGF-binding proteins associated with non-islet cell tumour induced hypoglycaemia
K. M. van Veggel et al.
GROWTH HORMONE & IGF RESEARCH (2014)
Knockdown of IEGF2R suppresses proliferation and induces apoptosis in hemangioma cells in vitro and in vivo
J. -M. Ou et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Insulin- like Growth Factor- II ( IGF- II) and IGF- II Analogs with Enhanced Insulin Receptor- a Binding Affinity Promote Neural Stem Cell Expansion*
Amber N. Ziegler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Transcriptional landscape of the prenatal human brain
Jeremy A. Miller et al.
NATURE (2014)
Insulin growth factor binding protein 7 is a novel target to treat dementia
Hope Y. Agbemenyah et al.
NEUROBIOLOGY OF DISEASE (2014)
Enhancement of Memories by Systemic Administration of Insulin-Like Growth Factor II
Sarah A. Stern et al.
NEUROPSYCHOPHARMACOLOGY (2014)
IGF2 Ameliorates Amyloidosis, Increases Cholinergic Marker Expression and Raises BMP9 and Neurotrophin Levels in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice
Tiffany J. Mellott et al.
PLOS ONE (2014)
Emerging evidence of insulin-like growth factor 2 as a memory enhancer: a unique animal model of cognitive dysfunction with impaired adult neurogenesis
Takashi Iwamoto et al.
REVIEWS IN THE NEUROSCIENCES (2014)
A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Ying Yu et al.
NATURE COMMUNICATIONS (2014)
The effect of insulin and insulin-like growth factors on hippocampus- and amygdala-dependent long-term memory formation
Sarah A. Stern et al.
LEARNING & MEMORY (2014)
Temporal expression patterns of insulin-like growth factor binding protein-4 in the embryonic and postnatal rat brain
Xiaohua Jiang et al.
BMC NEUROSCIENCE (2013)
Neurobiological markers of exercise-related brain plasticity in older adults
Michelle W. Voss et al.
BRAIN BEHAVIOR AND IMMUNITY (2013)
Positive Regulation of Insulin Signaling by Neuraminidase 1
Larbi Dridi et al.
DIABETES (2013)
Tumors, IGF-2, and Hypoglycemia: Insights From the Clinic, the Laboratory, and the Historical Archive
Yevgeniya Dynkevich et al.
ENDOCRINE REVIEWS (2013)
The IGF2 intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis
Mingzhu Liu et al.
GENES & DEVELOPMENT (2013)
Biochemical Characterization of Individual Human Glycosylated pro-Insulin-like Growth Factor (IGF)-II and big-IGF-II Isoforms Associated with Cancer
Sameer A. Greenall et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators
Hyeon-Sook Suh et al.
JOURNAL OF NEUROINFLAMMATION (2013)
Reduced Adult Hippocampal Neurogenesis and Working Memory Deficits in the Dgcr8-Deficient Mouse Model of 22q11.2 Deletion-Associated Schizophrenia Can Be Rescued by IGF2
Yasuo Ouchi et al.
JOURNAL OF NEUROSCIENCE (2013)
NCBI GEO: archive for functional genomics data sets-update
Tanya Barrett et al.
NUCLEIC ACIDS RESEARCH (2013)
Mechanisms That Determine the Internal Environment of the Developing Brain: A Transcriptomic, Functional and Ultrastructural Approach
Shane A. Liddelow et al.
PLOS ONE (2013)
Very long-term memories may be stored in the pattern of holes in the perineuronal net
Roger Y. Tsien
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection
Ingrid Kratzer et al.
FLUIDS AND BARRIERS OF THE CNS (2013)
IGF-2R-Mediated Signaling Results in Hypertrophy of Cultured Cardiomyocytes from Fetal Sheep
Kimberley C. W. Wang et al.
BIOLOGY OF REPRODUCTION (2012)
Early origins of heart disease: Low birth weight and the role of the insulin-like growth factor system in cardiac hypertrophy
Kimberley C. W. Wang et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2012)
Single-Transmembrane Domain IGF-II/M6P Receptor: Potential Interaction with G Protein and Its Association with Cholesterol-Rich Membrane Domains
Asha Amritraj et al.
ENDOCRINOLOGY (2012)
Neurodevelopmental effects of insulin-like growth factor signaling
John O'Kusky et al.
FRONTIERS IN NEUROENDOCRINOLOGY (2012)
Biology and significance of signalling pathways activated by IGF-II
Lynda K. Harris et al.
GROWTH FACTORS (2012)
The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module
Vanessa A. van Rahden et al.
HUMAN MOLECULAR GENETICS (2012)
The insulin-like growth factor (IGF) signaling axis and hepatitis C virus-associated carcinogenesis (Review)
Aldona Kasprzak et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
Activation of the P2X7 receptor induces migration of glial cells by inducing cathepsin B degradation of tissue inhibitor of metalloproteinase 1
Niamh Murphy et al.
JOURNAL OF NEUROCHEMISTRY (2012)
IκB Kinase/Nuclear Factor κB-Dependent Insulin-Like Growth Factor 2 (Igf2) Expression Regulates Synapse Formation and Spine Maturation via Igf2 Receptor Signaling
Michael J. Schmeisser et al.
JOURNAL OF NEUROSCIENCE (2012)
Gene Expression Profiling of Neural Stem Cells and Their Neuronal Progeny Reveals IGF2 as a Regulator of Adult Hippocampal Neurogenesis
Oliver Bracko et al.
JOURNAL OF NEUROSCIENCE (2012)
The Balance between Receptor Recycling and Trafficking toward Lysosomes Determines Synaptic Strength during Long-Term Depression
Monica Fernandez-Monreal et al.
JOURNAL OF NEUROSCIENCE (2012)
Activation of IGF-2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus
Kimberley C. W. Wang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
The many faces of insulin-like peptide signalling in the brain
Ana M. Fernandez et al.
NATURE REVIEWS NEUROSCIENCE (2012)
Insulin in the brain: There and back again
William A. Banks et al.
PHARMACOLOGY & THERAPEUTICS (2012)
IGF-II Promotes Stemness of Neural Restricted Precursors
Amber N. Ziegler et al.
STEM CELLS (2012)
Memory enhancement: consolidation, reconsolidation and insulin-like growth factor 2
Cristina M. Alberini et al.
TRENDS IN NEUROSCIENCES (2012)
Insulin-Like Growth Factor Binding Proteins: A Structural Perspective
Briony E. Forbes et al.
Frontiers in Endocrinology (2012)
Molecular Basis of Signaling Specificity of Insulin and IGF Receptors: Neglected Corners and Recent Advances
Kenneth Siddle
Frontiers in Endocrinology (2012)
Downregulation of hypothalamic insulin receptor expression elicits depressive-like behaviors in rats
Claudia A. Grillo et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories
Roberto Carlos Agis-Balboa et al.
EMBO JOURNAL (2011)
Plasma Distribution and Signaling Activities of IGF-II Precursors
Alicia G. Marks et al.
ENDOCRINOLOGY (2011)
Evolution of the Insulin-Like Growth Factor Binding Protein (IGFBP) Family
Daniel Ocampo Daza et al.
ENDOCRINOLOGY (2011)
Effects of Prenatal Ethanol Exposure on Postnatal Growth and the Insulin-Like Growth Factor Axis
Sofia Aros et al.
HORMONE RESEARCH IN PAEDIATRICS (2011)
Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats
Inma Castilla-Cortazar et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
A critical role for IGF-II in memory consolidation and enhancement
Dillon Y. Chen et al.
NATURE (2011)
Spatio-temporal transcriptome of the human brain
Hyo Jung Kang et al.
NATURE (2011)
IGFBP-3 Inhibits the Proliferation of Neural Progenitor Cells
Haviryaji S. G. Kalluri et al.
NEUROCHEMICAL RESEARCH (2011)
Deconstruction for Reconstruction: The Role of Proteolysis in Neural Plasticity and Disease
Baris Bingol et al.
NEURON (2011)
The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells
Maria K. Lehtinen et al.
NEURON (2011)
Insulin-Like Growth Factor 2 Receptor Is an IFNγ-Inducible Microglial Protein that Facilitates Intracellular HIV Replication
Hyeon-Sook Suh et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Evolution of Mannose 6-Phosphate Receptors (MPR300 and 46): Lysosomal Enzyme Sorting Proteins
S. K. Nadimpalli et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2010)
Estradiol Replacement Alters Expression of Genes Related to Neurotransmission and Immune Surveillance in the Frontal Cortex of Middle-Aged, Ovariectomized Rats
Miklos Sarvari et al.
ENDOCRINOLOGY (2010)
Mature IGF-II prevents the formation of big IGF-II/IGFBP-2 complex in the human circulation
Qing Qiu et al.
GROWTH HORMONE & IGF RESEARCH (2010)
Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS
Takeshi Nishijima et al.
NEURON (2010)
LEU27 INSULIN-LIKE GROWTH FACTOR-II, AN INSULIN-LIKE GROWTH FACTOR-II ANALOG, ATTENUATES DEPOLARIZATION-EVOKED GABA RELEASE FROM ADULT RAT HIPPOCAMPAL AND CORTICAL SLICES
A. Amritraj et al.
NEUROSCIENCE (2010)
Perspectives in mammalian IGFBP-3 biology: local vs. systemic action
Paulette M. Yamada et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)
Activation of Insulin-Like Growth Factor II Receptor Induces Mitochondrial-Dependent Apoptosis through Gαq and Downstream Calcineurin Signaling in Myocardial Cells
Chun-Hsien Chu et al.
ENDOCRINOLOGY (2009)
Differential Signaling Activation by Insulin and Insulin-Like Growth Factors I and II upon Binding to Insulin Receptor Isoform A
Antonella Sacco et al.
ENDOCRINOLOGY (2009)
Transport of mannose-6-phosphate receptors from the trans-Golgi network to endosomes requires Rab31
A. G. Rodriguez-Gabin et al.
EXPERIMENTAL CELL RESEARCH (2009)
Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP+PS1 transgenic mouse brains
A. Amritraj et al.
NEUROBIOLOGY OF AGING (2009)
IGFBP3 Colocalizes with and Regulates Hypocretin (Orexin)
Makoto Honda et al.
PLOS ONE (2009)
Prenatal choline supplementation in rats increases the expression of IGF2 and its receptor IGF2R and enhances IGF2-induced acetylcholine release in hippocampus and frontal cortex
Isabella Napoli et al.
BRAIN RESEARCH (2008)
Open clinical study of eye-drops containing tetrapeptides derived from substance P and insulin-like growth factor-1 for treatment of persistent corneal epithelial defects associated with neurotrophic keratopathy
N. Yamada et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2008)
Low doses of insulin-like growth factor I improve insulin resistance, lipid metabolism, and oxidative damage in aging rats
Maria Garcia-Fernandez et al.
ENDOCRINOLOGY (2008)
IGF-II/mannose 6-phosphate receptor activation induces metalloproteinase-9 matrix activity and increases plasminogen activator expression in H9c2 cardiomyoblast cells
Mu-Hsin Chang et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2008)
Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function
Ivy S. Samuels et al.
JOURNAL OF NEUROSCIENCE (2008)
The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis
J. L. Trejo et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin
Jin Han et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
The insulin paradox: aging, proteotoxicity and neurodegeneration
Ehud Cohen et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism
Laurent Kappeler et al.
PLOS BIOLOGY (2008)
Activation of endoproteolytic processing of insulin-like growth factor-II in fetal, early postnatal, and pregnant rats and persistence of circulating levels in postnatal life
Qing Qiu et al.
ENDOCRINOLOGY (2007)
Exercise builds brain health: key roles of growth factor cascades and inflammation (vol 9, pg 464, 2007)
Carl W. Cotman et al.
TRENDS IN NEUROSCIENCES (2007)
AKT/PKB signaling: Navigating downstream
Brendan D. Manning et al.
CELL (2007)
Mechanisms regulating imprinted genes in clusters
Carol A. Edwards et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
Effects of insulin-like growth factor 1 on synaptic excitability in cultured rat hippocampal neurons
Changhong Xing et al.
EXPERIMENTAL NEUROLOGY (2007)
Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains
Masayuki Itoh et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Genome-wide atlas of gene expression in the adult mouse brain
Ed S. Lein et al.
NATURE (2007)
Associations of blood levels of insulin-like growth factor (IGF)-I, IGF-II and IGF binding protein (IGFBP)-3 in schizophrenic Arab subjects
Abayomi O. Akanji et al.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2007)
Exercise builds brain health: key roles of growth factor cascades and inflammation
Carl W. Cotman et al.
TRENDS IN NEUROSCIENCES (2007)
Up-regulation of cation-independent mannose 6-phosphate receptor and endosomal-lysosomal markers in surviving neurons after 192-IgG-saporin administrations into the adult rat brain
Cheryl Hawkes et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Soluble IGF2 receptor rescues ApcMin/+ intestinal adenoma progression induced by Igf2 loss of imprinting
J Harper et al.
CANCER RESEARCH (2006)
Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway
C Hawkes et al.
JOURNAL OF NEUROSCIENCE (2006)
Insulin-like growth factor I interfaces with brain-derived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function
Q. Ding et al.
NEUROSCIENCE (2006)
The insulin-like growth factor system and its pleiotropic functions in brain
VC Russo et al.
ENDOCRINE REVIEWS (2005)
Insulin receptor signaling in long-term memory consolidation following spatial learning
JT Dou et al.
LEARNING & MEMORY (2005)
Role of pro-IGF-II processing by proprotein convertase 4 in human placental development
Q Qiu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Immunohistochemical distribution of cation-dependent mannose 6-phosphate receptors in the mouse central nervous system: comparison with that of cation-independent mannose 6-phophate receptors
Y Konishi et al.
NEUROSCIENCE LETTERS (2005)
The human brain mannose 6-phosphate glycoproteome: A complex mixture composed of multiple isoforms of many soluble lysosomal proteins
DE Sleat et al.
PROTEOMICS (2005)
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes?
E Steen et al.
JOURNAL OF ALZHEIMERS DISEASE (2005)
Differential gene expression of insulin receptor isoforms A and B and insulin receptor substrates 1, 2 and 3 in rat tissues:: modulation by aging and differentiation in rat adipose tissue
R Serrano et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2005)
IGF-I prevents glutamate-mediated Bax translocation and cytochrome C release in O4+ oligodendrocyte progenitors
JK Ness et al.
GLIA (2004)
Akt-1 expression level regulates CNS precursors
AD Sinor et al.
JOURNAL OF NEUROSCIENCE (2004)
Expression of insulin-like growth factors in remyelination following ethidium bromide-induced demyelination in the mouse spinal cord
S Fushimi et al.
NEUROPATHOLOGY (2004)
The cytoplasmic tail of the cation-independent mannose 6-phosphate receptor contains four binding sites for AP-l
P Ghosh et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Co-targeting IGF-1R and c-kit: synergistic inhibition of proliferation and induction of apoptosis in H 209 small cell lung cancer cells
A Camirand et al.
BRITISH JOURNAL OF CANCER (2004)
Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein-3 regulates cell survival and apoptosis
M Ikonen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Neuroprotective effects of insulin-like growth factor-binding protein ligand inhibitors in vitro and in vivo
KB Mackay et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2003)
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
BK Kaspar et al.
SCIENCE (2003)
Insulin-like growth factor-1 and post-ischemic brain injury
J Guan et al.
PROGRESS IN NEUROBIOLOGY (2003)
Insulin-like growth factor-II/mannose-6-phosphate receptor: Widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype
C Hawkes et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Mannose 6-phosphate receptors: New twists in the tale
P Ghosh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
M Holzenberger et al.
NATURE (2003)
Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved
G Pandini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
P-type lectins
NM Dahms et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2002)
Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy
E Carro et al.
JOURNAL OF NEUROSCIENCE (2001)
The acid-labile subunit (ALS) of the 150 kDa IGF-binding protein complex: an important but forgotten component of the circulating IGF system
YR Boisclair et al.
JOURNAL OF ENDOCRINOLOGY (2001)
Sorting of mannose 6-phosphate receptors mediated by the GGAs
R Puertollano et al.
SCIENCE (2001)
Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus
JL Trejo et al.
JOURNAL OF NEUROSCIENCE (2001)
IGF-II and IGF binding protein (IGFBP-1, ICFBP-3) gene expression in fetal rhesus monkey tissues during the second and third trimesters
CI Lee et al.
PEDIATRIC RESEARCH (2001)
Insulin and insulin-like growth factor I receptors: Similarities and differences in signal transduction
J Dupont et al.
HORMONE RESEARCH (2001)
Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis
RJ Lichtenwalner et al.
NEUROSCIENCE (2001)
Role of brain insulin receptor in control of body weight and reproduction
JC Brüning et al.
SCIENCE (2000)
Transport of drugs from the nasal cavity to the central nervous system
L Illum
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2000)
Structure and function of the type 1 insulin-like growth factor receptor
TE Adams et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2000)
Binding characteristics of pro-insulin-like growth factor-II from cancer patients: binary and ternary complex formation with IGF binding proteins-1 to -6
JJ Bond et al.
JOURNAL OF ENDOCRINOLOGY (2000)