相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。FOXG1 mediates the radiosensitivity of glioma cells through regulation of autophagy
Ning Xiao et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2021)
Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes
Shahla Shojaei et al.
FEBS JOURNAL (2020)
TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway
Ilya Ulasov et al.
INTERNATIONAL JOURNAL OF CANCER (2020)
Role of Sonic hedgehog signaling in cell cycle, oxidative stress, and autophagy of temozolomide resistant glioblastoma
Jessica R. Honorato et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Regulation of the autophagic PI3KC3 complex by laforin/malin E3-ubiquitin ligase, two proteins involved in Lafora disease
Pablo Sanchez-Martin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2020)
Clonal ZEB1-Driven Mesenchymal Transition Promotes Targetable Oncologic Antiangiogenic Therapy Resistance
Ankush Chandra et al.
CANCER RESEARCH (2020)
AnvirzelTM regulates cell death through inhibiting GSK-3 activity in human U87 glioma cells
Sule Terzioglu-Usak et al.
NEUROLOGICAL RESEARCH (2020)
A phase I study of sirolimus in combination with metronomic therapy (CHOAnome) in children with recurrent or refractory solid and brain tumors
Muna Qayed et al.
PEDIATRIC BLOOD & CANCER (2020)
Lipid Peroxidation Plays an Important Role in Chemotherapeutic Effects of Temozolomide and the Development of Therapy Resistance in Human Glioblastoma
Wei Wu et al.
TRANSLATIONAL ONCOLOGY (2020)
Inhibition of Cathepsin D (CTSD) enhances radiosensitivity of glioblastoma cells by attenuating autophagy
Wang Zheng et al.
MOLECULAR CARCINOGENESIS (2020)
Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma
Eun-Jin Yun et al.
CELL DEATH & DISEASE (2020)
Linc-RA1 inhibits autophagy and promotes radioresistance by preventing H2Bub1/USP44 combination in glioma cells
Jieling Zheng et al.
CELL DEATH & DISEASE (2020)
Investigating Glioblastoma Response to Hypoxia
Agathe L. Chedeville et al.
BIOMEDICINES (2020)
Clinicopathological Significance of Autophagy-related Proteins and its Association With Genetic Alterations in Gliomas
Samantha Tamrakar et al.
ANTICANCER RESEARCH (2019)
HERC3-Mediated SMAD7 Ubiquitination Degradation Promotes Autophagy-Induced EMT and Chemoresistance in Glioblastoma
Hong Li et al.
CLINICAL CANCER RESEARCH (2019)
DDR1 (discoidin domain receptor tyrosine kinase 1) drives glioblastoma therapy resistance by modulating autophagy
Anne Vehlow et al.
AUTOPHAGY (2019)
Intertumoral heterogeneity in patient-specific drug sensitivities in treatment-naive glioblastoma
Erlend Skaga et al.
BMC CANCER (2019)
Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux
Zhi-peng Wen et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Transcriptional Regulation of Autophagy: Mechanisms and Diseases
Chiara Di Malta et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)
Anti-Apoptotic and Anti-Oxidant Proteins in Glioblastomas: Immunohistochemical Expression of Beclin and DJ-1 and Its Correlation with Prognosis
Elia Guadagno et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
The FoxO-Autophagy Axis in Health and Disease
Zhiyong Cheng
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2019)
The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy
Marie Chollat-Namy et al.
CELL DEATH & DISEASE (2019)
Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells
Zhiyuan Zhu et al.
BIOMED RESEARCH INTERNATIONAL (2019)
Autophagy: A novel mechanism of chemoresistance in cancers
Xinyu Li et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide
Dejiang Pang et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
y The dual roles of autophagy in gliomagenesis and clinical therapy strategies based on autophagic regulation mechanisms
Fan Feng et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition
Tie Liu et al.
ONCOLOGY REPORTS (2019)
The miR-26a/AP-2 alpha/Nanog signaling axis mediates stem cell self-renewal and temozolomide resistance in glioma
Wenhuan Huang et al.
THERANOSTICS (2019)
A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma
Dan R. Laks et al.
NEURO-ONCOLOGY (2018)
Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy
Jiwei Wang et al.
AUTOPHAGY (2018)
Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers
Mireia Nager et al.
AUTOPHAGY (2018)
Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression
Chunming Jiang et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma
Galia Tiram et al.
FASEB JOURNAL (2018)
miR-519a enhances chemosensitivity and promotes autophagy in glioblastoma by targeting STAT3/Bcl2 signaling pathway
Hong Li et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Tamoxifen overrides autophagy inhibition in Beclin-1-deficient glioma cells and their resistance to adenovirus-mediated oncolysis via upregulation of PUMA and BAX
Natalya Kaverina et al.
ONCOGENE (2018)
Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response
Sabine Hombach-Klonisch et al.
PHARMACOLOGY & THERAPEUTICS (2018)
MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells
Sarmistha Talukdar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Mechanisms controlling the anti-neoplastic functions of FoxO proteins
Tianyun Hou et al.
SEMINARS IN CANCER BIOLOGY (2018)
Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival
Lian Wang et al.
CELL DEATH & DISEASE (2018)
Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma
Matthew A. Taylor et al.
APOPTOSIS (2018)
Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis
Mariachiara Buccarelli et al.
CELL DEATH & DISEASE (2018)
Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics
Jurgen Kriel et al.
SCIENTIFIC REPORTS (2018)
Autophagic flux response and glioblastoma sensitivity to radiation
Achilleas G. Mitrakas et al.
CANCER BIOLOGY & MEDICINE (2018)
Targeting mTOR in Glioblastoma: Rationale and Preclinical/Clinical Evidence
Carmen Mecca et al.
DISEASE MARKERS (2018)
Chemoresistance and the Self-Maintaining Tumor Microenvironment
Gulcen Yeldag et al.
CANCERS (2018)
Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin
Timothy P. Kegelman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells
Alessandro Magini et al.
HUMAN MOLECULAR GENETICS (2017)
Sinomenine Hydrochloride Inhibits Human Glioblastoma Cell Growth through Reactive Oxygen Species Generation and Autophagy-Lysosome Pathway Activation: An In Vitro and In Vivo Study
Yumao Jiang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Temozolomide does not influence the transcription or activity of matrix metalloproteinases 9 and 2 in glioma cell lines
Yuta Suzuki et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2017)
Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination
Xin Zhang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)
Distinct Radiomic Phenotypes Define Glioblastoma TP53-PTEN-EGFR Mutational Landscape
Pascal O. Zinn et al.
NEUROSURGERY (2017)
Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo
Nathaniel H. Boyd et al.
JCI INSIGHT (2017)
Autophagy-induced KDR/VEGFR-2 activation promotes the formation of vasculogenic mimicry by glioma stem cells
Hai-Bo Wu et al.
AUTOPHAGY (2017)
MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma
Tianzhi Huang et al.
CANCER CELL (2017)
Macropinocytosis of Bevacizumab by Glioblastoma Cells in the Perivascular Niche Affects their Survival
Gaelle Mueller-Greven et al.
CLINICAL CANCER RESEARCH (2017)
Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents
Ciska Verbaanderd et al.
ECANCERMEDICALSCIENCE (2017)
Malatl activates autophagy and promotes cell proliferation by sponging miR-101 and upregulating STMN1, RAB5A and ATG4D expression in glioma
Zhenqiang Fu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Glioblastoma-derived cells in vitro unveil the spectrum of drug resistance capability - comparative study of tumour chemosensitivity in different culture systems
Monika Witusik-Perkowska et al.
BIOSCIENCE REPORTS (2017)
EMAP-II sensitize U87MG and glioma stem-like cells to temozolomide via induction of autophagy-mediated cell death and G2/M arrest
Qi Yu et al.
CELL CYCLE (2017)
Autophagy and multidrug resistance in cancer
Ying-Jie Li et al.
CHINESE JOURNAL OF CANCER (2017)
Autophagy inhibitors chloroquine and LY294002 enhance temozolomide cytotoxicity on cutaneous melanoma cell lines in vitro
Oxana O. Ryabaya et al.
ANTI-CANCER DRUGS (2017)
Structural biology of the core autophagy machinery
Hironori Suzuki et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2017)
Molecular interplay between mutant p53 proteins and autophagy in cancer cells
Marco Cordani et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2017)
How to train glioma cells to die: molecular challenges in cell death
Jeffrey Wojton et al.
JOURNAL OF NEURO-ONCOLOGY (2016)
Suppression of autophagy impedes glioblastoma development and induces senescence
Noor Gammoh et al.
AUTOPHAGY (2016)
Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve
Michael I. Koukourakis et al.
BRITISH JOURNAL OF CANCER (2016)
Glioblastoma in the Canton of Zurich, Switzerland revisited: 2005 to 2009
Dorothee Gramatzki et al.
CANCER (2016)
Targeting autophagy to sensitive glioma to temozolomide treatment
Yuanliang Yan et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells
Takashi Shingu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2016)
Knockdown of retinoblastoma protein may sensitize glioma cells to cisplatin through inhibition of autophagy
Xiangyu Liu et al.
NEUROSCIENCE LETTERS (2016)
Glioblastoma, hypoxia and autophagy: a survival-prone 'menage-a-trois'
Soha Jawhari et al.
CELL DEATH & DISEASE (2016)
Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas
Lukas Jennewein et al.
ONCOTARGET (2016)
Autophagy and p53
Eileen White
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)
BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells
Iwona Anna Ciechomska et al.
SCIENTIFIC REPORTS (2016)
Glioblastoma: Overview of Disease and Treatment
Mary Elizabeth Davis
CLINICAL JOURNAL OF ONCOLOGY NURSING (2016)
ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells
Jing-Hong Chen et al.
AUTOPHAGY (2015)
Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways
Jianbin Zhang et al.
AUTOPHAGY (2015)
Molecular Mechanisms of Autophagy in the Cardiovascular System
Damian Gatica et al.
CIRCULATION RESEARCH (2015)
HMGB1 modulates Lewis cell autophagy and promotes cell survival via RAGE-HMGB1-Erk1/2 positive feedback during nutrient depletion
Zhaoliang Su et al.
IMMUNOBIOLOGY (2015)
ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells
Rutger K. Balvers et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Icariin Promotes Angiogenic Differentiation and Prevents Oxidative Stress-Induced Autophagy in Endothelial Progenitor Cells
Yubo Tang et al.
STEM CELLS (2015)
Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma
E. Singer et al.
CELL DEATH & DISEASE (2015)
MiR224-3p inhibits hypoxia-induced autophagy by targeting autophagy-related genes in human glioblastoma cells
Xing Guo et al.
ONCOTARGET (2015)
Combined Epidermal Growth Factor Receptor and Beclin1 Autophagic Protein Expression Analysis Identifies Different Clinical Presentations, Responses to Chemo- and Radiotherapy, and Prognosis in Glioblastoma
Paolo Tini et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Radiation-Induced Autophagy Contributes to Cell Death and Induces Apoptosis Partly in Malignant Glioma Cells
Guk Heui Jo et al.
CANCER RESEARCH AND TREATMENT (2015)
An Overview of Autophagy: Morphology, Mechanism, and Regulation
Katherine R. Parzych et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
When cytoprotective autophagy isn't. and even when it is
David A. Gewirtz
AUTOPHAGY (2014)
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
Myrna R. Rosenfeld et al.
AUTOPHAGY (2014)
Autophagy and lysosomal related protein expression patterns in human glioblastoma
Alexandra Giatromanolaki et al.
CANCER BIOLOGY & THERAPY (2014)
GPER Mediates Activation of HIF1α/VEGF Signaling by Estrogens
Ernestina Marianna De Francesco et al.
CANCER RESEARCH (2014)
Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells
Mario L. Suva et al.
CELL (2014)
Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling
A. Ko et al.
CELL DEATH AND DIFFERENTIATION (2014)
Regulation of autophagy by the Rab GTPase network
X. Ao et al.
CELL DEATH AND DIFFERENTIATION (2014)
Efficacy of rapamycin against glioblastoma cancer stem cells
M. Mendiburu-Elicable et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2014)
Inhibition of DNA Double-Strand Break Repair by the Dual PI3K/mTOR Inhibitor NVP-BEZ235 as a Strategy for Radiosensitization of Glioblastoma
Carlos Rodrigo Gil del Alcazar et al.
CLINICAL CANCER RESEARCH (2014)
Methylation Silencing of ULK2, an Autophagy Gene, Is Essential for Astrocyte Transformation and Tumor Growth
Sudhanshu Shukla et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins
Daniel J. Klionsky et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Hypoxia-inducible factor-1 and associated upstream and downstream proteins in the pathophysiology and management of glioblastoma
Matthew Womeldorff et al.
NEUROSURGICAL FOCUS (2014)
Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy
Encouse B. Golden et al.
NEUROSURGICAL FOCUS (2014)
Beclin 1, an autophagy-related gene, augments apoptosis in U87 glioblastoma cells
Xin Huang et al.
ONCOLOGY REPORTS (2014)
FOXO transcription factors: key regulators of cellular quality control
Ashley E. Webb et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone
M. Yazdankhah et al.
CELL DEATH & DISEASE (2014)
PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways
L. Chang et al.
CELL DEATH & DISEASE (2014)
Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib
Hongming Pan et al.
SCIENTIFIC REPORTS (2014)
Standards of care and novel approaches in the management of glioblastoma multiforme
Andreas F. Hottinger et al.
CHINESE JOURNAL OF CANCER (2014)
ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma
Faisal Thayyullathil et al.
FEBS OPEN BIO (2014)
Gossypol enhances radiation-induced autophagy in glioblastoma multiforme
Hoda Keshmiri-Neghab et al.
GENERAL PHYSIOLOGY AND BIOPHYSICS (2014)
NVP-BEZ235, a novel dual PI3K/mTOR inhibitor, enhances the radiosensitivity of human glioma stem cells in vitro
Wen-juan Wang et al.
ACTA PHARMACOLOGICA SINICA (2013)
Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma
J. Shen et al.
BRITISH JOURNAL OF CANCER (2013)
A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments
Kenta Masui et al.
CARCINOGENESIS (2013)
Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease-Links to Parkinson's Disease
Laura D. Osellame et al.
CELL METABOLISM (2013)
ATM pathway is essential for ionizing radiation-induced autophagy
Nan Liang et al.
CELLULAR SIGNALLING (2013)
Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy
Hitoshi Nakatogawa
AUTOPHAGY: MOLECULES AND MECHANISMS (2013)
Phosphoinositide 3-kinases as accelerators and brakes of autophagy
Fergal O'Farrell et al.
FEBS JOURNAL (2013)
Mechanisms of Radiation Toxicity in Transformed and Non-Transformed Cells
Ronald-Allan M. Panganiban et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Autophagy and ionizing radiation in tumors: The survive or not survive dilemma
Silvia Palumbo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2013)
Autophagy: A critical regulator of cellular metabolism and homeostasis
Stefan W. Ryter et al.
MOLECULES AND CELLS (2013)
FIP200 is required for maintenance and differentiation of postnatal neural stem cells
Chenran Wang et al.
NATURE NEUROSCIENCE (2013)
The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells
S. Galavotti et al.
ONCOGENE (2013)
Overexpression of DRAM enhances p53-dependent apoptosis
Masahiro Takahashi et al.
CANCER MEDICINE (2013)
Role of the Crosstalk between Autophagy and Apoptosis in Cancer
Minfei Su et al.
JOURNAL OF ONCOLOGY (2013)
Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells
Patricia Vazquez et al.
AUTOPHAGY (2012)
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
Jose A. Martina et al.
AUTOPHAGY (2012)
Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and jnk activation
Cristina Trejo-Solis et al.
BMC CANCER (2012)
Autophagy in Brain Tumors: A New Target for Therapeutic Intervention
Niroop Kaza et al.
BRAIN PATHOLOGY (2012)
Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
Yu-Long Hu et al.
CANCER RESEARCH (2012)
Resveratrol Enhances the Antitumor Effects of Temozolomide in Glioblastoma via ROS-dependent AMPK-TSC-mTOR Signaling Pathway
Yuan Yuan et al.
CNS NEUROSCIENCE & THERAPEUTICS (2012)
Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications
Liuqi Yang et al.
EXPERIMENTAL CELL RESEARCH (2012)
O6-Methylguanine-Methyltransferase (MGMT) Promoter Methylation Status in Glioma Stem-Like Cells is Correlated to Temozolomide Sensitivity Under Differentiation-Promoting Conditions
Claire Villalva et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)
Autophagy and cancer - issues we need to digest
Emma Y. Liu et al.
JOURNAL OF CELL SCIENCE (2012)
Astrocyte-Specific Expression Patterns Associated with the PDGF-Induced Glioma Microenvironment
Amanda M. Katz et al.
PLOS ONE (2012)
Chaperone-mediated autophagy: a unique way to enter the lysosome world
Susmita Kaushik et al.
TRENDS IN CELL BIOLOGY (2012)
Long-term survival of patients suffering from glioblastoma multiforme treated with tumor-treating fields
Aaron Michael Rulseh et al.
WORLD JOURNAL OF SURGICAL ONCOLOGY (2012)
Inhibition of Autophagy as a Strategy to Augment Radiosensitization by the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235
George J. Cerniglia et al.
MOLECULAR PHARMACOLOGY (2012)
A critical role for UVRAG in apoptosis
Xiaocheng Yin et al.
AUTOPHAGY (2011)
Novel Phosphoinositide 3-Kinase/mTOR Dual Inhibitor, NVP-BGT226, Displays Potent Growth-Inhibitory Activity against Human Head and Neck Cancer Cells In Vitro and In Vivo
Kwang-Yu Chang et al.
CLINICAL CANCER RESEARCH (2011)
The dynamic nature of autophagy in cancer
Alec C. Kimmelman
GENES & DEVELOPMENT (2011)
Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity
Wenzhuo Zhuang et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage
Sandrine Lepine et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes
Tassula Proikas-Cezanne et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
Genetic variations in VEGF and VEGFR2 and glioblastoma outcome
S. Sjostrom et al.
JOURNAL OF NEURO-ONCOLOGY (2011)
Association between AKT/mTOR signalling pathway and malignancy grade of human gliomas
Xue-yuan Li et al.
JOURNAL OF NEURO-ONCOLOGY (2011)
Impact of therapy on quality of life, neurocognitive function and their correlates in glioblastoma multiforme: a review
Roger Henriksson et al.
JOURNAL OF NEURO-ONCOLOGY (2011)
The Autophagy Protein Atg12 Associates with Antiapoptotic Bcl-2 Family Members to Promote Mitochondrial Apoptosis
Assaf D. Rubinstein et al.
MOLECULAR CELL (2011)
Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
Troy T. Rohn et al.
NEUROBIOLOGY OF DISEASE (2011)
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre et al.
SCIENCE (2011)
Role of BNIP3 in proliferation and hypoxia-induced autophagy: implications for personalized cancer therapies
Meghan B. Azad et al.
TOWARD PERSONALIZED MEDICINE FOR CANCER (2010)
Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation
Mitsuko Hayashi-Nishino et al.
AUTOPHAGY (2010)
ATG12 Conjugation to ATG3 Regulates Mitochondrial Homeostasis and Cell Death
Lilliana Radoshevich et al.
CELL (2010)
Methods in Mammalian Autophagy Research
Noboru Mizushima et al.
CELL (2010)
Hypoxia-induced autophagy: cell death or cell survival?
Nathalie M. Mazure et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Eaten alive: a history of macroautophagy
Zhifen Yang et al.
NATURE CELL BIOLOGY (2010)
Autophagy and Metabolism
Joshua D. Rabinowitz et al.
SCIENCE (2010)
Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma
Qi-Wen Fan et al.
SCIENCE SIGNALING (2010)
Autophagosome formation in mammalian cells
Chloe Burman et al.
SEMINARS IN IMMUNOPATHOLOGY (2010)
Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis
Yushan Zhu et al.
PROTEIN & CELL (2010)
Long-term Temozolomide Treatment Induces Marked Amino Metabolism Modifications and an Increase in TMZ Sensitivity in Hs683 Oligodendroglioma Cells
Delphine Lamoral-Theys et al.
NEOPLASIA (2010)
Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance
Kimmo J. Hatanpaa et al.
NEOPLASIA (2010)
Autophagy Suppresses Tumorigenesis through Elimination of p62
Robin Mathew et al.
CELL (2009)
Life and death partners: apoptosis, autophagy and the cross-talk between them
A. Eisenberg-Lerner et al.
CELL DEATH AND DIFFERENTIATION (2009)
Autophagy mediates the mitotic senescence transition
Andrew R. J. Young et al.
GENES & DEVELOPMENT (2009)
Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2
Cole J. Ferguson et al.
HUMAN MOLECULAR GENETICS (2009)
The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells
Stephanie L. Lomonaco et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Molecular Predictors of Progression-Free and Overall Survival in Patients With Newly Diagnosed Glioblastoma: A Prospective Translational Study of the German Glioma Network
Michael Weller et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
Gregory Bellot et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Chang Hwa Jung et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
Mitsuko Hayashi-Nishino et al.
NATURE CELL BIOLOGY (2009)
Stat3 Expression and Its Correlation with Proliferation and Apoptosis/Autophagy in Gliomas
Valentina Caldera et al.
Journal of Oncology (2009)
Monitoring autography in glioblastoma with antibody aganist isoform B of human microtuble-associated protein 1 light chain 3
Hiroshi Aoki et al.
AUTOPHAGY (2008)
Autophagy functions in programmed cell death
Deborah L. Berry et al.
AUTOPHAGY (2008)
Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3
Meghan B. Azad et al.
AUTOPHAGY (2008)
Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy
Anja Apel et al.
CANCER RESEARCH (2008)
p53 target genes Sestrin1 and Sestrin2 connect genotoxic stress and mTOR signaling
Andrei V. Budanov et al.
CELL (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
To Die or Not to Die: That is the Autophagic Question
Maria Maiuri et al.
CURRENT MOLECULAR MEDICINE (2008)
Autophagy-inducing agents augment the antitumor effect of telomerase-selective oncolytic adenovirus OBP-405 on glioblastoma cells
T. Yokoyama et al.
GENE THERAPY (2008)
Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways
Guomei Tang et al.
HUMAN MOLECULAR GENETICS (2008)
Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan
Sith Sathornsumetee et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Essential role for Nix in autophagic maturation of erythroid cells
Hector Sandoval et al.
NATURE (2008)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
NATURE (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
Inhibition of N-(4-hydroxyphenyl)retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells
Meenakshi Tiwari et al.
CARCINOGENESIS (2008)
SiRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy
Edmond Y. W. Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
Serhiy Pankiv et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes
Andrew R. J. Young et al.
JOURNAL OF CELL SCIENCE (2006)
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
Diane Crighton et al.
CELL (2006)
Two domains are critical for the nuclear localization of soluble adenylyl cyclase
QP Feng et al.
BIOCHIMIE (2006)
Essential roles of Atg5 and FADD in autophagic cell death - Dissection of autophagic cell death into vacuole formation and cell death
JO Pyo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant gliorna cells by inducing autophagy
S Daido et al.
CANCER RESEARCH (2005)
The role of autophagy in cancer development and response to therapy
Y Kondo et al.
NATURE REVIEWS CANCER (2005)
Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells
H Takeuchi et al.
BRITISH JOURNAL OF CANCER (2004)
Class III phosphoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes
A Tassa et al.
BIOCHEMICAL JOURNAL (2003)
Reactive astrocytes express bis, a Bcl-2-binding protein, after transient forebrain ischemia
MY Lee et al.
EXPERIMENTAL NEUROLOGY (2002)
SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation
A Nara et al.
CELL STRUCTURE AND FUNCTION (2002)