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Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas
Katarzyna Modzelewska et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Force sensing by mechanical extension of the Src family kinase substrate p130Cas
Yasuhiro Sawada et al.
CELL (2006)
Shigella applies molecular mimicry to subvert vinculin and invade host cells
Tina Izard et al.
JOURNAL OF CELL BIOLOGY (2006)
From the membrane to the nucleus and back again: bifunctional focal adhesion proteins
Martial Hervy et al.
CURRENT OPINION IN CELL BIOLOGY (2006)
Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors
S. K. Mitra et al.
ONCOGENE (2006)
Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri
Cyril Hamiaux et al.
EMBO REPORTS (2006)
A conformational switch in vinculin drives formation and dynamics of a talin-vinculin complex at focal adhesions
Daniel M. Cohen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
OspE2 of Shigella sonnei is required for the maintenance of cell architecture of bacterium-infected cells
M Miura et al.
INFECTION AND IMMUNITY (2006)
p130Cas: a versatile scaffold in signaling networks
P Defilippi et al.
TRENDS IN CELL BIOLOGY (2006)
Interaction partners for human ZNF384/CIZ/NMP4 - zyxin as a mediator for p130CAS signaling?
H Janssen et al.
EXPERIMENTAL CELL RESEARCH (2006)
Structure of the α-actinin-vinculin head domain complex determined by cryo-electron microscopy
DF Kelly et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility and deficits in actin remodeling
LM Hoffman et al.
JOURNAL OF CELL BIOLOGY (2006)
Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA
R Tsutsumi et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Paxillin phosphorylation sites mapped by mass spectrometry
DJ Webb et al.
JOURNAL OF CELL SCIENCE (2005)
Talin phosphorylation sites mapped by mass spectrometry
B Ratnikov et al.
JOURNAL OF CELL SCIENCE (2005)
The mechanisms and dynamics of αvβ3 integrin clustering in living cells
C Cluzel et al.
JOURNAL OF CELL BIOLOGY (2005)
Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement
M Yoshigi et al.
JOURNAL OF CELL BIOLOGY (2005)
αvβ3-integrin-dependent activation of focal adhesion kinase mediates NF-κB activation and motogenic activity by HIV-1 Tat in endothelial cells
C Urbinati et al.
JOURNAL OF CELL SCIENCE (2005)
Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness
MC Brown et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Invasion of endothelial cells by Neisseria meningitidis requires cortactin recruitment by a phosphoinositide-3-kinase/Rac1 signalling pathway triggered by the lipo-oligosaccharide
M Lambotin et al.
JOURNAL OF CELL SCIENCE (2005)
Flavoridin inhibits Yersinia enterocolitica uptake into fibronectin-adherent HeLa cells
A Scibelli et al.
FEMS MICROBIOLOGY LETTERS (2005)
Src kinase regulation by phosphorylation and dephosphorylation
R Roskoski
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Cellular invasion by Staphylococcus aureus reveals a functional link between focal adhesion kinase and cortactin in integrin-mediated internalisation
F Agerer et al.
JOURNAL OF CELL SCIENCE (2005)
Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration
AJ Woods et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin
DM Cohen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Disruption of target cell adhesion structures by the Yersinia effector YopH requires interaction with the substrate domain of p130Cas
L Mogemark et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2005)
The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein-induced bone formation
M Morinobu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Clinging to life: cell to matrix adhesion and cell survival
PJ Reddig et al.
CANCER AND METASTASIS REVIEWS (2005)
Cell invasion and IL-8 production pathways initiated by YadA of Yersinia pseudotuberculosis require common signalling molecules (FAK, c-Src, Ras) and distinct cell factors
J Eitel et al.
CELLULAR MICROBIOLOGY (2005)
Regulating cell migration: calpains make the cut
SJ Franco et al.
JOURNAL OF CELL SCIENCE (2005)
Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion
NO Carragher et al.
TRENDS IN CELL BIOLOGY (2004)
FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly
DJ Webb et al.
NATURE CELL BIOLOGY (2004)
Calpain-mediated proteolysis of talin regulates adhesion dynamics
SJ Franco et al.
NATURE CELL BIOLOGY (2004)
Isoform specific function of calpain 2 in regulating membrane protrusion
S Franco et al.
EXPERIMENTAL CELL RESEARCH (2004)
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF-H1
T Matsuzawa et al.
EMBO JOURNAL (2004)
Expression and distribution of β1 integrins in in vitro-induced M cells:: implications for Yersinia adhesion to Peyer's patch epithelium
N Hamzaoui et al.
CELLULAR MICROBIOLOGY (2004)
Mechanism of blebbistatin inhibition of myosin II
M Kovács et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Vinculin is proteolyzed by calpain during platelet aggregation: 95 kDa cleavage fragment associates with the platelet cytoskeleton
K Serrano et al.
CELL MOTILITY AND THE CYTOSKELETON (2004)
Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation
JR Peterson et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Focal adhesion regulation of cell behavior
MA Wozniak et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells
Y Obara et al.
JOURNAL OF CELL SCIENCE (2004)
High-throughput structural biology in drug discovery: Protein kinases
TJ Stout et al.
CURRENT PHARMACEUTICAL DESIGN (2004)
HIV-1 tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells
HK Avraham et al.
JOURNAL OF IMMUNOLOGY (2004)
Involvement of secreted Aspergillus fumigatus proteases in disruption of the actin fiber cytoskeleton and loss of focal adhesion sites in infected A549 lung pneumocytes
TV Kogan et al.
JOURNAL OF INFECTIOUS DISEASES (2004)
Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis
S Ishibe et al.
MOLECULAR CELL (2004)
Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells
R Zaidel-Bar et al.
JOURNAL OF CELL SCIENCE (2003)
Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction
LA Cooper et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Ras-induced serine phosphorylation of the focal adhesion protein paxillin is mediated by the Raf→ MEK→ ERK pathway
MA Woodrow et al.
EXPERIMENTAL CELL RESEARCH (2003)
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation
T Sakai et al.
GENES & DEVELOPMENT (2003)
Zyxin and paxillin proteins: focal adhesion plaque LIM domain proteins go nuclear
Y Wang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2003)
Maximal adherence and invasion of INT 407 cells by Campylobacter jejuni requires the CadF outermembrane protein and microfilament reorganization
MR Monteville et al.
MICROBIOLOGY-SGM (2003)
Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis
S Ishibe et al.
MOLECULAR CELL (2003)
Interaction between the Yersinia protein tyrosine phosphatase YopH and eukaryotic Cas/Fyb is an important virulence mechanism
F Deleuil et al.
CELLULAR MICROBIOLOGY (2003)
Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells
A Unkmeir et al.
MOLECULAR MICROBIOLOGY (2002)
Dynamin2 and cortactin regulate actin assembly and filament organization
DA Schafer et al.
CURRENT BIOLOGY (2002)
Calponin homology domains at a glance
E Korenbaum et al.
JOURNAL OF CELL SCIENCE (2002)
Candida albicans expresses a focal adhesion kinase-like protein that undergoes increased tyrosine phosphorylation upon yeast cell adhesion to vitronectin and the EA.hy 926 human endothelial cell line
G Santoni et al.
INFECTION AND IMMUNITY (2002)
Enteropathogenic Escherichia coli induces modification of the focal adhesions of infected host cells
Y Shifrin et al.
CELLULAR MICROBIOLOGY (2002)
Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells
AJ Woods et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The spectrin repeat:: a structural platform for cytoskeletal protein assemblies
K Djinovic-Carugo et al.
FEBS LETTERS (2002)
Pleckstrin homology domains and the cytoskeleton
MA Lemmon et al.
FEBS LETTERS (2002)
The paxillin LD motifs
DA Tumbarello et al.
FEBS LETTERS (2002)
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling
M Hagel et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Interaction of zyxin, a focal adhesion protein, with the E6 protein from human papillomavirus type 6 results in its nuclear translocation
YY Degenhardt et al.
JOURNAL OF VIROLOGY (2001)
The role of adenovirus E4orf4 protein in viral replication and cell killing
PE Branton et al.
ONCOGENE (2001)
Talin, a host cell protein, interacts directly with the translocated intimin receptor, Tir, of enteropathogenic Escherichia coli, and is essential for pedestal formation
VV Cantarelli et al.
CELLULAR MICROBIOLOGY (2001)
Focal adhesion kinase is involved in mechanosensing during fibroblast migration
HB Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Targeting of zyxin to sites of actin membrane interaction and to the nucleus
DA Nix et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Degradation of focal adhesion proteins paxillin and p130cas by caspases or calpains in apoptotic Rat-1 and L929 cells
SR Shim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
De novo formation of focal complex-like structures in host cells by invading Streptococci
V Ozeri et al.
MOLECULAR MICROBIOLOGY (2001)
YadA, the multifaceted Yersinia adhesin
Y El Tahir et al.
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2001)
Calpain cleavage promotes talin binding to the β3 integrin cytoplasmic domain
B Yan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activation of Arp2/3 complex-mediated actin polymerization by cortactin
T Uruno et al.
NATURE CELL BIOLOGY (2001)
The interaction of titin and α-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism
P Young et al.
EMBO JOURNAL (2000)
SU6656, a selective Src family kinase inhibitor, used to probe growth factor signaling
RA Blake et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Involvement of focal adhesion kinase in Escherichia coli invasion of human brain microvascular endothelial cells
MA Reddy et al.
INFECTION AND IMMUNITY (2000)
The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages
DS Black et al.
CELLULAR MICROBIOLOGY (2000)
Adenovirus E4 open reading frame 4-induced apoptosis involves dysregulation of Src family kinases
JN Lavoie et al.
JOURNAL OF CELL BIOLOGY (2000)
Stales and transitions during forced unfolding of a single spectrin repeat
PF Lenne et al.
FEBS LETTERS (2000)
Interaction of the τ2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix
L Yang et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Competitive binding to a charged leucine motif represses transformation by a papillomavirus E6 oncoprotein
J Bohl et al.
VIROLOGY (2000)
A nonpeptide integrin antagonist can inhibit epithelial cell ingestion of Streptococcus pyogenes by blocking formation of integrin α5β1-fibronectin-M1 protein complexes
D Cue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells
V Petit et al.
JOURNAL OF CELL BIOLOGY (2000)
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