Antioxidant and anti-ageing effects of enzymatic polysaccharide from Pleurotus eryngii residue

The wide industrial cultivation of Pleurotus eryngii (P. eryngii) has resulted in the massive production of mushroomresidues (MR) with low-efficiency utilization. In the present study, the P. eryngii enzymatic residue polysaccharide (PERP) was obtained from the P. eryngii residues. The characterization analysis showed that PERP was polysaccharides comprised of five kinds of monosaccharides with molecular weight of 2.05 x 10(3) Da. PERP also showed rough surface and appeared as spherical structure dispersed in aqueous solution. The animal experiment analysis demonstrated that PERP exhibited potential anti-ageing effects on the brain, liver, kidney and skin, possibly by scavenging reactive radicals, improving the antioxidant status, supressing lipid peroxidation, enhancing organ functions and ameliorating histopathological damage. These results may provide a reference for the efficient utilization of P. eryngii residues in exploring MR-derived functional foods or drugs that delay the ageing process. (C) 2021 Elsevier B.V. All rights reserved.

Automated summary

The study found that PERP extracted from Pleurotus eryngii residues may serve as a potential anti-aging agent, positively impacting the brain, liver, kidneys, and skin. This polysaccharide, comprised of multiple monosaccharides, with a moderate molecular weight and spherical structure, showed promising effects in animal experiments.