Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months

We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or no symptoms. The first infection persisted for 80 days and the second for 62 days. Clearance of infection occurred 40 and 41 days, respectively, after development of detectable antibodies. Both cases were identified incidentally in an investigation of reinfection in a cohort of 133,266 laboratory-confirmed infected persons.

Automated summary

We report two cases of viremic and prolonged active infection with SARS-CoV-2 where the viral genome remained stable for two months, but with minimal or no symptoms. Clearance of infection occurred 40 and 41 days after detectable antibodies appeared in each case. These cases were incidentally identified during an investigation on reinfection among a cohort of 133,266 laboratory-confirmed infected individuals.