期刊
IEEE TRANSACTIONS ON MEDICAL IMAGING
卷 40, 期 3, 页码 818-828出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2020.3037771
关键词
Image segmentation; Retinopathy; Transfer learning; Benchmark testing; Diabetes; Lesions; Task analysis; Diabetic retinopathy; lesion segmentation; grading; transfer learning
Researchers have constructed a fine-grained annotated DR dataset to address the performance and interpretability issues faced by current DR diagnosis systems. This dataset contains two types of detailed annotated images, enabling in-depth studies on DR diagnosis.
People with diabetes are at risk of developing an eye disease called diabetic retinopathy (DR). This disease occurs when high blood glucose levels cause damage to blood vessels in the retina. Computer-aided DR diagnosis has become a promising tool for the early detection and severity grading of DR, due to the great success of deep learning. However, most current DR diagnosis systems do not achieve satisfactory performance or interpretability for ophthalmologists, due to the lack of training data with consistent and fine-grained annotations. To address this problem, we construct a large fine-grained annotated DR dataset containing 2,842 images (FGADR). Specifically, this dataset has 1,842 images with pixel-level DR-related lesion annotations, and 1,000 images with image-level labels graded by six board-certified ophthalmologists with intra-rater consistency. The proposed dataset will enable extensive studies on DR diagnosis. Further, we establish three benchmark tasks for evaluation: 1. DR lesion segmentation; 2. DR grading by joint classification and segmentation; 3. Transfer learning for ocular multi-disease identification. Moreover, a novel inductive transfer learning method is introduced for the third task. Extensive experiments using different state-of-the-art methods are conducted on our FGADR dataset, which can serve as baselines for future research. Our dataset will be released in https://csyizhou.github.io/FGADR/.
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