期刊
HUMAN BRAIN MAPPING
卷 42, 期 7, 页码 2214-2235出版社
WILEY
DOI: 10.1002/hbm.25361
关键词
attention-deficit/hyperactivity disorder; borderline personality disorder; gray matter; impulsivity; magnetic resonance imaging; meta-analysis; psychoradiology; voxel-based morphometry
资金
- China Postdoctoral Science Foundation [2019M653421]
- National Natural Science Foundation of China [31800963, 81621003, 81820108018, 82027808]
The study provides an integrated delineation of gray matter substrates related to trait impulsivity, highlighting volumetric GM alterations in prefrontal, temporal, and parietal cortices. Furthermore, the modulatory effects of age and gender in impulsivity-GM volume associations were identified, advancing understanding of brain GM morphometry features underlying trait impulsivity with potential implications for clinical diagnosis and intervention.
Trait impulsivity is a multifaceted personality characteristic that contributes to maladaptive life outcomes. Although a growing body of neuroimaging studies have investigated the structural correlates of trait impulsivity, the findings remain highly inconsistent and heterogeneous. Herein, we performed a systematic review to depict an integrated delineation of gray matter (GM) substrates of trait impulsivity and a meta-analysis to examine concurrence across previous whole-brain voxel-based morphometry studies. The systematic review summarized the diverse findings in GM morphometry in the past literature, and the quantitative meta-analysis revealed impulsivity-related volumetric GM alterations in prefrontal, temporal, and parietal cortices. In addition, we identified the modulatory effects of age and gender in impulsivity-GM volume associations. The present study advances understanding of brain GM morphometry features underlying trait impulsivity. The findings may have practical implications in the clinical diagnosis of and intervention for impulsivity-related disorders.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据