4.4 Letter

Pediatric lipoblastoma with a novel EEF1A1-PLAG1 fusion

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Article Pathology

Lipoblastomas presenting in older children and adults: analysis of 22 cases with identification of novel PLAG1 fusion partners

Karen Fritchie et al.

Summary: Lipoblastomas may occur in older children and adults and may be difficult to recognize due to their predominantly adipocytic or fibrous appearance.

MODERN PATHOLOGY (2021)

Article Oncology

Pediatric fibromyxoid soft tissue tumor with PLAG1 fusion: A novel entity?

Catherine T. Chung et al.

Summary: The classification of undifferentiated soft tissue tumors is evolving with molecular analysis. The report presents three unique soft tissue tumors in young children with fibromyxoid histology and rare PLAG1 fusions. These tumors may be associated with a novel fibromyxoid neoplasm in childhood, highlighting the need for further research to confirm the relationship.

GENES CHROMOSOMES & CANCER (2021)