4.6 Review

New Insights into the Biological Properties of Eucalyptus-derived essential oil: A Promising Green Anti-Cancer Drug

期刊

FOOD REVIEWS INTERNATIONAL
卷 38, 期 -, 页码 598-633

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/87559129.2021.1877300

关键词

Anti-tumour; cancer diseases; secondary compounds; cell apoptosis; cytotoxicity; myrtaceae; oncology; pharmaceuticals; ethnopharmacological; plant-derived products

资金

  1. Trans-disciplinary Research Grant Scheme (TRGS) 2018 under the Ministry of Higher Education (MOHE), Malaysia [TRGS/1/2018/UPM/01/2/2]

向作者/读者索取更多资源

Cancer is a condition where cells grow uncontrollably and may spread to other parts of the body. Eucalyptus-derived essential oils have potential in treating or preventing cancer, but more evidence is needed to confirm their efficacy.
Cancer is a condition in which cells grow uncontrollably and may metastasis to other parts of the body. Despite the recent advances in synthesising new anticancer agents, plant-derived compounds are traditionally considered as the primary health care approaches in some parts of the world. Eucalyptus-derived essential oils are the rich resources of active phytochemicals, which have been used for treating or preventing different ailments. However, there is less literature addressing the bioactivity of Eucalyptus-derived phytochemicals in the treatment of cancers. In this review paper, we summarised the existing evidence on the wide-spectrum activity of Eucalyptus-derived essential oil against malignancies. Our review highlighted that Eucalyptus-derived essential oil contains a wide variety of secondary metabolites, and thus capable of slowing or inhibiting the cancerous cell lines in vitro and in vivo conditions. We also summarized the achievement in the anti-tumour activity of nanoparticles, the application of plant-based essential oils in food safety, and the application of green extraction technologies. It can be concluded that Eucalyptus has immense potential to cure malignancies, and such information can be used in further studies. Notwithstanding the advantages, Eucalyptus-derived essential oils can be poisonous; therefore, more evidence is still required to confirm the efficacy of Eucalyptus-derived essential oil.

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