4.6 Review

Noncanonical interactions of G proteins and β-arrestins: from competitors to companions

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Noncanonical scaffolding of Gαi and β-arrestin by G protein-coupled receptors

Jeffrey S. Smith et al.

Summary: This study demonstrates that GPCRs can facilitate a direct interaction between G(alpha i) protein family members and beta-arrestins, regardless of their classical G(alpha) protein subtype coupling. These findings introduce a novel GPCR signaling mechanism that is distinct from canonical G protein activation.

SCIENCE (2021)

Article Multidisciplinary Sciences

Structure of the neurotensin receptor 1 in complex with β-arrestin 1

Weijiao Huang et al.

NATURE (2020)

Article Multidisciplinary Sciences

Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc

Dean P. Staus et al.

NATURE (2020)

Article Multidisciplinary Sciences

Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor

Carl-Mikael Suomivuori et al.

SCIENCE (2020)

Article Biochemistry & Molecular Biology

β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors

Lauren M. Slosky et al.

Article Biochemistry & Molecular Biology

TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome

Reid H. J. Olsen et al.

NATURE CHEMICAL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Key phosphorylation sites inGPCRs orchestrate the contribution of β-Arrestin 1 inERK1/2 activation

Mithu Baidya et al.

EMBO REPORTS (2020)

Article Biochemistry & Molecular Biology

New Insights into Arrestin Recruitment to GPCRs

Martin Spillmann et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor

Yang Lee et al.

NATURE (2020)

Article Multidisciplinary Sciences

Phosphorylation barcode-dependent signal bias of the dopamine D1 receptor

Ali I. Kaya et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Agonist-induced formation of unproductive receptor-G12 complexes

Najeah Okashah et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Chemistry, Medicinal

Emerging Role of Compartmentalized G Protein-Coupled Receptor Signaling in the Cardiovascular Field

Bianca Plouffe et al.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2020)

Review Cell Biology

The structural basis of the arrestin binding to GPCRs

Vsevolod V. Gurevich et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2019)

Article Multidisciplinary Sciences

Variable G protein determinants of GPCR coupling selectivity

Najeah Okashah et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemistry & Molecular Biology

Illuminating G-Protein-Coupling Selectivity of GPCRs

Asuka Inoue et al.

Article Cell Biology

A complex structure of arrestin-2 bound to a G protein-coupled receptor

Wanchao Yin et al.

CELL RESEARCH (2019)

Article Biochemistry & Molecular Biology

Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex

Anthony H. Nguyen et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)

Article Biochemistry & Molecular Biology

Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations

Laura M. Wingler et al.

Article Biochemical Research Methods

An online resource for GPCR structure determination and analysis

Christian Munk et al.

NATURE METHODS (2019)

Article Cell Biology

Different mode of arrestin-3 binding at the human Y1 and Y2 receptor

Lizzy Wanka et al.

CELLULAR SIGNALLING (2018)

Article Biochemistry & Molecular Biology

Mini G protein probes for active G protein-coupled receptors (GPCRs) in live cells

Qingwen Wan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Multidisciplinary Sciences

Catalytic activation of β-arrestin by GPCRs

Kelsie Eichel et al.

NATURE (2018)

Article Multidisciplinary Sciences

Molecular mechanism of GPCR-mediated arrestin activation

Naomi R. Latorraca et al.

NATURE (2018)

Review Biotechnology & Applied Microbiology

Biased signalling: from simple switches to allosteric microprocessors

Jeffrey S. Smith et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

Article Multidisciplinary Sciences

Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect

David Cotnoir-White et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Biochemistry & Molecular Biology

Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors

Madhu Chaturvedi et al.

TRENDS IN BIOCHEMICAL SCIENCES (2018)

Article Multidisciplinary Sciences

Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR

Yutaro Shiraishi et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Lack of beta-arrestin signaling in the absence of active G proteins

Manuel Grundmann et al.

NATURE COMMUNICATIONS (2018)

Review Biochemistry & Molecular Biology

The Molecular Basis of G Protein-Coupled Receptor Activation

William I. Weis et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 87 (2018)

Review Cell Biology

Mechanisms of signalling and biased agonism in G protein-coupled receptors

Denise Wootten et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Manifold roles of beta-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9

Louis M. Luttrell et al.

SCIENCE SIGNALING (2018)

Article Biochemistry & Molecular Biology

Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation

Jeffrey S. Smith et al.

SCIENCE SIGNALING (2018)

Article Biotechnology & Applied Microbiology

A comprehensive map of molecular drug targets

Rita Santos et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Review Pharmacology & Pharmacy

Phosphorylation of G Protein-Coupled Receptors: From the Barcode Hypothesis to the Flute Model

Zhao Yang et al.

MOLECULAR PHARMACOLOGY (2017)

Article Multidisciplinary Sciences

Selectivity determinants of GPCR-G-protein binding

Tilman Flock et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

Functional selectivity of GPCR-directed drug action through location bias

Roshanak Irannejad et al.

NATURE CHEMICAL BIOLOGY (2017)

Article Multidisciplinary Sciences

Allosteric beta-blocker isolated from a DNA-encoded small molecule library

Seungkirl Ahn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis

Thomas J. Cahill et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling

Jialu Wang et al.

NATURE COMMUNICATIONS (2017)

Review Cell Biology

G protein-coupled receptor kinases: Past, present and future

Konstantin E. Komolov et al.

CELLULAR SIGNALLING (2017)

Review Cell Biology

GPCR desensitization: Acute and prolonged phases

Sudarshan Rajagopal et al.

CELLULAR SIGNALLING (2017)

Article Biochemistry & Molecular Biology

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

Andrew S. Dixon et al.

ACS CHEMICAL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

Alex R. B. Thomsen et al.

Review Biochemistry & Molecular Biology

The β-Arrestins: Multifunctional Regulators of G Protein-coupled Receptors

Jeffrey S. Smith et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Multidisciplinary Sciences

Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

Brian T. DeVree et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor

Alem W. Kahsai et al.

NATURE CHEMICAL BIOLOGY (2016)

Article Biochemical Research Methods

Quantitative assessment of fluorescent proteins

Paula J. Cranfill et al.

NATURE METHODS (2016)

Article Multidisciplinary Sciences

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

Sophie J. Bradley et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Functional competence of a partially engaged GPCR-β-arrestin complex

Punita Kumari et al.

NATURE COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

Structural insights into μ-opioid receptor activation

Weijiao Huang et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Divergent Transducer-specific Molecular Efficacies Generate Biased Agonism at a G Protein-coupled Receptor ( GPCR)

Ryan T. Strachan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Visualization of arrestin recruitment by a G-protein-coupled receptor

Arun K. Shukla et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

Endosomal generation of cAMP in GPCR signaling

Jean-Pierre Vilardaga et al.

NATURE CHEMICAL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis

Nikoleta G. Tsvetanova et al.

NATURE CHEMICAL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

β-Arrestin-1 directly interacts with Gas and regulates its function

Bo Li et al.

FEBS LETTERS (2013)

Article Biochemistry & Molecular Biology

Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin

Timothy N. Feinstein et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

The Chemokine Receptor CCR1 Is Constitutively Active, Which Leads to G Protein-independent, β-Arrestin-mediated Internalization

C. Taylor Gilliland et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Multidisciplinary Sciences

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Andrew C. Kruse et al.

NATURE (2013)

Article Multidisciplinary Sciences

Conformational biosensors reveal GPCR signalling from endosomes

Roshanak Irannejad et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

Mary P. Hall et al.

ACS CHEMICAL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Differential G-protein-coupled Receptor Phosphorylation Provides Evidence for a Signaling Bar Code

Adrian J. Butcher et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Multidisciplinary Sciences

Crystal structure of the β2 adrenergic receptor-Gs protein complex

Soren G. F. Rasmussen et al.

NATURE (2011)

Article Biochemistry & Molecular Biology

CODA-RET reveals functional selectivity as a result of GPCR heteromerization

Eneko Urizar et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Retromer terminates the generation of cAMP by internalized PTH receptors

Timothy N. Feinstein et al.

NATURE CHEMICAL BIOLOGY (2011)

Review Pharmacology & Pharmacy

β-arrestin-mediated receptor trafficking and signal transduction

Sudha K. Shenoy et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2011)

Article Pharmacology & Pharmacy

Selectively Engaging β-Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance

Jonathan D. Violin et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)

Article Biochemistry & Molecular Biology

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

Sebastien Ferrandon et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

Florian Mullershausen et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Persistent cAMP-Signals Triggered by Internalized G-Protein-Coupled Receptors

Davide Calebiro et al.

PLOS BIOLOGY (2009)

Article Multidisciplinary Sciences

Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo

E. Stefan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Pharmacology & Pharmacy

β-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis

DL Hunton et al.

MOLECULAR PHARMACOLOGY (2005)

Article Multidisciplinary Sciences

Defective lymphocyte chemotaxis in β-arresting2-and GRK6-deficient mice

AM Fong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds

LM Luttrell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)