期刊
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
卷 33, 期 -, 页码 50-60出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ejpn.2021.02.001
关键词
Fetal alcohol syndrome; FASD; Intervention; Therapy; Systematic review
资金
- Bavarian State Ministry of Health and Care
- German Federal Ministry of Health
- Robert-Vogel-Stiftung (RVS)
- Soziale Beratungs-und Betreuungsdienste (SBB) Bayern gGmbH
The article presents a systematic literature review of evidence-based intervention strategies for children and adolescents with FASD, identifying some effective therapeutic interventions in these patients. While improvements into a normal range are rare, the interventions can alleviate negative consequences of prenatal alcohol exposure and relieve daily burdens.
Introduction: Brain function deficits cause strong negative impacts for the everyday lives of children and adolescents with fetal alcohol spectrum disorders (FASD). Therefore, evidence-based intervention pro-grams that are specifically designed for patients with FASD are needed but still scarce. The aim of the presented article is a systematic literature review of evidence-based intervention strategies for children and adolescents with FASD. Materials and methods: A comprehensive systematic literature search was conducted in several relevant databases to identify randomized-controlled intervention studies for children and adolescents with FASD. Results: We identified 25 randomized-controlled studies regarding interventions in FASD. Overall, evidence indicating that some therapeutic interventions are effective in children and adolescents with FASD was found. Even though evidence-based interventions rarely lead to improvements of performance into a normal range, those measures can alleviate negative consequences of prenatal alcohol exposure and relieve daily burdens. Conclusion: There are only a few randomized-controlled trials regarding therapy research for children and adolescents with FASD. Their results indicate that especially the combination of parent and child sessions present a promising approach for the treatment of FASD. Positive treatment effects of interventions seem to be domain specific, except for interventions regarding self-regulation or social interaction. (c) 2021 Published by Elsevier Ltd on behalf of European Paediatric Neurology Society.
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