4.5 Review

Intramolecular Heck Reaction in Total Synthesis of Natural Products: An Update

期刊

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2021, 期 14, 页码 2057-2076

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.202100071

关键词

Alkaloid; Heck cyclization; Macrolide; Terpenoid; Total synthesis

资金

  1. Council of Scientific and Industrial Research, New Delhi
  2. Indian Association for the Cultivation of Science
  3. SERB, Department of Science and Technology [CRG/2019/001664]
  4. Council of Scientific and Industrial Research India [02(0294)/17/EMR-II]

向作者/读者索取更多资源

The intramolecular Heck reaction plays a significant role in synthesizing natural products by constructing various cyclic scaffolds. It serves as a strategic step in the synthesis of different natural products.
This review highlights the application of intramolecular Heck reaction in total synthesis of natural products which were successfully synthesized in recent years (2013 to 2019). Heck cyclization was used as one of the strategic steps for constructions of wide variety of cyclic scaffolds essential for preparation of different natural products.

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