期刊
EUROPEAN JOURNAL OF HEART FAILURE
卷 23, 期 3, 页码 352-380出版社
WILEY
DOI: 10.1002/ejhf.2115
关键词
Heart failure; Cardiomyopathy; HFrEF; HFpEF; HFmrEF; Stages of heart failure; Definition of heart failure
This document proposes a universal definition of heart failure as a clinical syndrome and revised stages of HF, as well as a new classification based on left ventricular ejection fraction (LVEF) levels. The classification includes HFrEF, HFmrEF, HFpEF, and HFimpEF based on LVEF percentages.
In this document, we propose a universal definition of heart failure (HF) as a clinical syndrome with symptoms and/or signs caused by a structural and/or functional cardiac abnormality and corroborated by elevated natriuretic peptide levels and/or objective evidence of pulmonary or systemic congestion. We also propose revised stages of HF as: At risk for HF (Stage A), Pre-HF (Stage B), Symptomatic HF (Stage C) and Advanced HF (Stage D). Finally, we propose a new and revised classification of HF according to left ventricular ejection fraction (LVEF). This includes HF with reduced ejection fraction (HFrEF): symptomatic HF with LVEF <= 40%; HF with mildly reduced ejection fraction (HFmrEF): symptomatic HF with LVEF 41-49%; HF with preserved ejection fraction (HFpEF): symptomatic HF with LVEF >= 50%; and HF with improved ejection fraction (HFimpEF): symptomatic HF with a baseline LVEF <= 40%, a >= 10 point increase from baseline LVEF, and a second measurement of LVEF > 40%.
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