4.5 Article

Nonenzymatic Electrochemical Sensor for Wearable Interstitial Fluid Glucose Monitoring

期刊

ELECTROANALYSIS
卷 34, 期 2, 页码 415-422

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.202060601

关键词

Nonenzymatic; Sensor; Interstitial Fluid; Glucose; Diabetes

资金

  1. National Natural Science Foundation of China [21635001]
  2. State Key Laboratory of Bioelectronics, Southeast University

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The study presents a nonenzymatic electrochemical sensor for wearable glucose monitoring, which demonstrates acceptable selectivity and reliability for continuous glucose detection up to 30 days, as well as good biocompatibility. A fully integrated wearable glucose monitoring system with wireless connectivity to a smartphone has been developed.
We report on a nonenzymatic electrochemical sensor for wearable glucose monitoring in interstitial fluid. The sensor exhibited acceptable selectivity and reliability for continuous glucose detection for up to 30 days. The sensor tip is coated with polyurethane, and the biocompatibility of the tip is investigated by tissue staining. A fully integrated wearable glucose monitoring system is developed with a wireless connection with a smartphone. The test results are in agreement with reference methods. So, we believe the sensor is promising for the development of a continuous glucose monitoring system and diabetes management.

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