期刊
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
卷 210, 期 -, 页码 -出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2020.111825
关键词
Florfenicol; Salvia Miltiorrhiza polysaccharide; Immune response; Broilers
资金
- Subsidized Project for Cultivating Innovative Ability of Postgraduates of Hebei Province [CXZZBS2019096]
- Hebei Province Innovation Capacity Promotion Project-Hebei Veterinary Biotechnology Innovation Center Open Project [20567668H]
- Precision Animal Husbandry Discipline Group Construction Project of Hebei Agricultural University [1090064]
FFC can inhibit the growth performance of broilers, but does not significantly damage their immune function; the combination of FFC and SMPs can enhance immune responses in broilers by increasing certain immune indicators in the blood.
To explore the effect of florfenicol (FFC) combined with Salvia miltiorrhiza polysaccharide (SMPs) on immune function of Broilers. One hundred and twenty-one-day-old chicks were chosen and divided into 6 groups. The group A received standard basal diet only, the group B received a basal diet with FFC (0.15 g/L diet), and the group C, D, E received a basal diet with FFC (0.15 g/L diet) and SMPs (1.25 g/L, 2.5 g/L, 5 g/L diet),the group F received a basal diet with SMPs (5 g/L diet). FFC can significantly inhibit the growth performance of broilers, but has no significant damage to the immune function of broilers. The combination of FFC and SMPs can improve the growth performance of broilers, increase the number of leukocyte subtypes in blood (P < 0.05), increase the number of Newcastle disease (ND) and avian influenza (AI) antibodies in blood, the number of immunoglobulins, and the content of cytokines (P < 0.05). In addition, it significantly improve the lymphocyte conversion rate of broiler peripheral blood (P < 0.05). So that, synergistic use of FFC and SMPs can enhance immune responses in Broilers.
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