期刊
DRUG AND ALCOHOL DEPENDENCE
卷 220, 期 -, 页码 -出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.drugalcdep.2020.108496
关键词
e-Cigarettes; Alcohol; Adolescence; Longitudinal analysis; Tobacco
资金
- National Institute for Drug Abuse at NIH [K01DA042950, R01DA033296]
- National Cancer Institute [R01CA229617]
- National Cancer Institute and Food and Drug Administration Center for Tobacco Products [U54CA180905]
- Tobacco Related Disease Research Program (TRDRP) [27-IR-0034]
The study suggests a bidirectional association between e-cigarette and alcohol use among adolescents, with gender influencing this association. These connections can serve as markers for identifying youth at risk for future alcohol and e-cigarette use.
Introduction: Evidence on prospective bidirectional associations between e-cigarette and alcohol use among adolescents can inform prevention and policy but is largely absent from the literature. Methods: Data were drawn from a prospective cohort of students attending 10 Los Angeles high schools (N = 3396; baseline mean age = 14.1, SD = 0.4). Students completed surveys every 6-months from 2013 to 2017; 8 total waves. Analyses were restricted to (a) individuals who were never users of alcohol (N = 2394) or (b) individuals who were never users of e-cigarettes (N = 2704) at baseline. Repeated-measures, generalized linear mixed models were used to estimate the adjusted odds of past 6-month alcohol and e-cigarette initiation, in separate models. Results: Among alcohol never-users at baseline, 15.7 % (N = 375) initiated alcohol use over the study period. Compared to never-users of e-cigarettes, those who reported use of e-cigarettes had 3.5 times the odds of subsequently initiating alcohol use in the following wave (OR = 3.54; 95 % CI: 2.81, 4.47). Stronger associations were observed for males (OR = 4.94; 95 % CI: 3.78, 6.45) than for females (OR = 3.21; 95 % CI: 2.33, 4.41; p(interaction) = 0.04). Among e-cigarette never-users at baseline, 26.3 % (N = 709) initiated e-cigarette use over the study period. Compared to never-users of alcohol, those who reported use of alcohol had 3.2 times the odds of subsequently initiating e-cigarette use in the following wave (OR = 3.23; 95 % CI: 2.68, 3.89). This association did not differ by gender. Conclusions: E-cigarette and alcohol use can be markers to identify youth at risk for future alcohol and e-cigarette use, respectively. Research examining mechanisms underlying these associations is needed to infer causality.
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