Treatment personalization in gastrointestinal neuroendocrine tumors

Opinion statementThe clinical scenario of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) is continuously changing due to significant improvements in the definition of their molecular landscapes and the introduction of innovative therapeutic approaches. Many efforts are currently employed in the integration of the genetics/epigenetics and clinical information. This is leading to an improvement of tumor classification, prognostic stratification and ameliorating the management of patients based on a personalized approach.

Automated summary

The clinical scenario of GEP-NENs is continuously evolving due to improvements in defining their molecular landscapes and introducing innovative therapeutic approaches. Efforts are being made to integrate genetics/epigenetics and clinical information to improve tumor classification, prognostic stratification, and personalized patient management.