4.5 Article

Sensational developments in somatosensory development?

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CURRENT OPINION IN NEUROBIOLOGY
卷 66, 期 -, 页码 212-223

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CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2020.12.011

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  1. Canadian Institutes of Health Research (CIHR)

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This overview discusses recent advances in the development of the components of the somatosensory system, including peripheral sensory neurons, central nervous system circuits, and higher structures like the somatosensory cortex. It also covers the role of neuronal activity in somatosensory development, formation of somatotopic maps, insights into human somatosensory development, and the connection between aberrant somatosensation and neurodevelopmental disorders.
This is an overview of the most recent advances pertaining to the development of the cardinal components of the somatosensory system: the peripheral sensory neurons that perceive somatosensory stimuli, the first line central nervous system circuits that modulate them, and the higher structures such as the somatosensory cortex that eventually compute a motor response to them. Here, I also review the most recent findings concerning the role of neuronal activity in somatosensory development, formation of somatotopic maps, insights into human somatosensory development and the link between aberrant somatosensation and neurodevelopmental disorders.

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