期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 67, 期 -, 页码 26-34出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2020.11.009
关键词
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资金
- National Natural Science Foundation of China [21908004, 21808008]
- Fundamental Research Funds for the Central Universities [buctrc201801]
- Novo Nordisk Foundation [NNF10CC1016517]
- Knut and Alice Wallenberg Foundation
Researchers have extensively studied and engineered yeast cell factories to produce a variety of oleochemicals from renewable feedstocks. Recent progress includes exploring alternative renewable feedstocks like xylose and L-arabinose, as well as investigating the utilization of C1 compounds for third generation yeast based biorefineries for oleochemical production.
Biosynthesis of oleochemicals enables sustainable production of natural and unnatural alternatives from renewable feedstocks. Yeast cell factories have been extensively studied and engineered to produce a variety of oleochemicals, focusing on both central carbon metabolism and lipid metabolism. Here, we review recent progress towards oleochemical synthesis in yeast based biorefineries, as well as utilization of alternative renewable feedstocks, such as xylose and L-arabinose. We also review recent studies of C1 compound utilization or co-utilization and discuss how these studies can lead to third generation yeast based biorefineries for oleochemical production.
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