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Klebsiella oxytoca and Emerging Nosocomial Infections

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CURRENT MICROBIOLOGY
卷 78, 期 4, 页码 1115-1123

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SPRINGER
DOI: 10.1007/s00284-021-02402-2

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Klebsiella oxytoca is emerging as an important opportunistic pathogen causing hospital infections, especially posing a high risk for immunocompromised patients. It can lead to a variety of diseases, including colitis and infective endocarditis, in addition to common urinary and respiratory tract infections. The bacterium exhibits resistance to a wide range of antibiotics.
Klebsiella oxytoca is rising as a significant opportunistic pathogen causing nosocomial infections in neonates as well as adults. This pathogen's prevalence varies from 2 to 24%, but outbreaks of infections due to multidrug-resistant strains can be fatal in immunocompromised individuals with comorbidities. Klebsiella oxytoca is responsible for a wide range of ailments from colitis to infective endocarditis, other than the common urinary and respiratory tract infections. The microbe's pathogenicity has been attributed to cytotoxins' production- Tilivalline and Tilimycin, in some intestinal disorders. Klebsiella oxytoca is reported to be resistant to a wide range of antibiotics. Here, we have tried to showcase a brief overview of the emergence of Klebsiella oxytoca in healthcare facilities and the nature of resistance in this species of Klebsiella.

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