期刊
CURRENT EYE RESEARCH
卷 46, 期 8, 页码 1247-1250出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/02713683.2021.1874027
关键词
COVID-19; virus; retinitis; optic neuritis; blindness
资金
- COVID-19 Emergency Response Project of Wuhan Science and Technology Department [2020020201010018]
This study documented a case of an older female with concomitant acquired monocular blindness and COVID-19, highlighting the potential for retinal complications and severe vision loss in COVID-19 patients. Physicians should be aware of the possibility of fundus abnormalities or sudden vision loss in coronavirus-infected patients.
Objective: We documented an older female with Coronavirus(CoV) Disease 2019 (COVID-19) and concomitant acquired monocular blindness. We examined this phenomenon in order to understand COVID-19 better. Methods: We observed an older female with COVID-19 and concomitant acquired monocular blindness. The following indicators were monitored during the course of the disease: ocular examinations, flash visual evoked potential examination, a blood test for COVID-19 IgM antibodies, as well as nasopharyngeal swab and tear sample tests for COVID-19 nucleic acid. Results: The patient's visual acuity for the left eye was NLP and the intraocular pressure was 51 mmHg. Keratic precipitates similar to mutton-fat were spread over the corneal endothelium of the left eye. The funduscopic examination of the patient's left eye revealed severe retinal arterial ischemia, and the color of the retina was off-white. Compared to the right eye, the flash visual evoked potential examination revealed a moderate decrease in P2 wave amplitude for the left eye. A blood test was positive for COVID-19 IgM antibodies, and a nasopharyngeal swab test taken for COVID-19 nucleic acid was positive on May 4, 2020. A sample of the patient's tears was taken, and the nucleic acid test for COVID-19 was still positive two weeks later. Conclusions: Our study was the first to find that acute viral retinitis could occur in patients with COVID-19 and severe blindness could be associated with SARS-CoV-2 infection. Therefore, physicians should consider the possibility of coronavirus infection in patients with an abnormal fundus or suddenly vision loss.
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