4.8 Article

The irritant receptor TRPA1 mediates the mosquito repellent effect of catnip

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Summary: Domestic cats and other felids exhibit a characteristic response by rubbing their faces and heads against catnip and silver vine, which is triggered by the iridoid nepetalactol. This behavior transfers nepetalactol onto their faces and heads, repelling mosquitoes, and increasing plasma beta-endorphin levels. Through the mu-opioid system, this self-anointing behavior serves as an important example of chemical pest defense in nonhuman mammals.

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