期刊
CRITICAL REVIEWS IN BIOTECHNOLOGY
卷 41, 期 4, 页码 580-593出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/07388551.2020.1869692
关键词
Ergothioneine; antioxidant; mushroom; biosynthesis; fermentation; metabolic engineering
资金
- National Key R&D Program of China [2019YFA0905700]
- National Natural Science Foundation of China [21878151]
- Jiangsu Synergetic Innovation Center for Advanced BioManufacture [XTE1829]
- General Program on Natural Science Research Project of Higher Education of Jiangsu [18KJB530007]
- Scientific Research Project for Postgraduate in Jiangsu Province [SJCX20_0311]
Ergothioneine, a sulfur-containing histidine derivative, is widely used in the food and cosmetics industries for its excellent antioxidant properties. It plays a significant role in anti-aging and disease prevention. This review discusses the functions and applications of ergothioneine, its biosynthetic pathways, strategies for increasing production, efficient extraction and detection methods, as well as proposals for enhancing yield and future development prospects.
Ergothioneine is a sulfur-containing histidine derivative, that possessesexcellent antioxidant activity and has been used in the food and cosmetics industries. It plays a significant role in anti-aging and the prevention of various diseases. This review will briefly introduce the functions and applications of ergothioneine, elaborate the biosynthetic pathways of ergothioneine and describe several strategies to increase the production of ergothioneine. Then the efficient extraction and detection methods of ergothioneine will be presented. Finally, several proposals are put forward to increase the yield of ergothioneine, and the development prospects of ergothioneine will be discussed.
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