期刊
CORNEA
卷 41, 期 1, 页码 31-38出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/ICO.0000000000002675
关键词
dry eye; pain; refractive surgery
资金
- Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Clinical Sciences RD (CSRD) [I01 CX002015]
- Biomedical Laboratory R&D (BLRD) Service [I01 BX004893]
- Department of Defense Gulf War Illness Research Program (GWIRP) [W81XWH-20-1-0579]
- Vision Research Program (VRP) [W81XWH-20-1-0820]
- National Eye Institute [R01EY026174, R61EY032468]
- NIH Center Core Grant [P30EY014801]
- Research to Prevent Blindness Unrestricted Grant
- Dr. Ronald and Alicia Lepke Grant
- Lee and Claire Hager Grant
- Robert Farr Family Grant
- Grant and Diana Stanton-Thornbrough
- Robert Baer Family Grant
- Emilyn Page and Mark Feldberg Grant
- Jose Ferreira de Melo Grant
- Richard and Kathy Lesser Grant
- Michele and Ted Kaplan Grant
- Richard Azar Family Grant
This study characterized ocular pain symptoms in individuals with and without a history of refractive surgery (RS). The results showed that individuals with a history of RS developed ocular pain soon after surgery, which persisted for years. The symptom profiles were similar between those with and without RS, and both groups can treat pain with topical and systemic approaches.
Purpose: This study characterized ocular pain symptoms in individuals with and without a history of refractive surgery (RS) using a cross-sectional survey of individuals with ocular pain. Methods: A link to an anonymous survey was posted on a corneal neuralgia Facebook group that included individuals with ocular pain from any etiology and sent to individuals seen in our clinic with ocular pain. The survey asked about medical history, ocular pain symptoms (using standardized questionnaires), and treatment responses. Respondents were split into 2 groups based on a history of RS. Results: One hundred one individuals responded to the survey. The mean age for all respondents was 41.6 +/- 15.6 years, and 50% reported a history of RS. A total of 46% of individuals with a history of RS reported that their ocular pain started within 1 month of surgery, with median pain duration of 36 (interquartile range 22-84) months. The median Dry Eye Questionnaire-5 (range 0-22) scores were 16 and 15 for the RS and no-RS groups, respectively. Most individuals in both groups characterized their pain as burning (score >= 1: RS, 86%; no-RS, 80%) and reported evoked pain to wind, light, or temperature (score >= 1: RS, 97%; no-RS, 85%). Fifty-nine of 101 individuals responded to treatment questions. Individuals in both groups reported >30% improvement in pain symptoms with some topical and systemic approaches. Conclusions: Individuals with a history of RS developed ocular pain soon after surgery, which persisted for years. Symptom profiles were similar between those with and without RS. Topical and systemic approaches can treat pain in both groups.
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