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ACE-inhibitory activity and ACE-inhibiting peptides in different cheese varieties
Robert Sieber et al.
DAIRY SCIENCE & TECHNOLOGY (2010)
The use of ultrasound for enzymatic preparation of ACE-inhibitory peptides from wheat germ protein
Junqiang Jia et al.
FOOD CHEMISTRY (2010)
A novel angiotensin I converting enzyme inhibitory peptide from tuna frame protein hydrolysate and its antihypertensive effect in spontaneously hypertensive rats
Sang-Hoon Lee et al.
FOOD CHEMISTRY (2010)
Oxygen radical absorbance capacity of peptides from egg white protein ovotransferrin and their interaction with phytochemicals
Wu-Yang Huang et al.
FOOD CHEMISTRY (2010)
Impact of processing on stability of angiotensin I-converting enzyme (ACE) inhibitory peptides obtained from tuna cooking juice
Jyh-Sheng Hwang
FOOD RESEARCH INTERNATIONAL (2010)
A new approach for identification of novel antihypertensive peptides from egg proteins by QSAR and bioinformatics
Kaustav Majumder et al.
FOOD RESEARCH INTERNATIONAL (2010)
Optimization of sour milk fermentation for the production of ACE-inhibitory peptides and purification of a novel peptide from whey protein hydrolysate
Daodong Pan et al.
INTERNATIONAL DAIRY JOURNAL (2010)
Antihypertensive Properties of Lactoferricin B-Derived Peptides
Pedro Ruiz-Gimenez et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)
Egg-Derived Peptide IRW Inhibits TNF-α-Induced Inflammatory Response and Oxidative Stress in Endothelial Cells
Wuyang Huang et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)
Isolation of an Antihypertensive Peptide from Alcalase Digest of Spirulina platensis
Jun Lu et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)
Antioxidative and Angiotensin-1-Converting Enzyme Inhibitory Potential of a Pacific Hake (Merluccius productus) Fish Protein Hydrolysate Subjected to Simulated Gastrointestinal Digestion and Caco-2 Cell Permeation
Anusha G. P. Samaranayaka et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)
Peptides surviving the simulated gastrointestinal digestion of milk proteins: Biological and toxicological implications
Gianluca Picariello et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2010)
The (193-209) 17-residues peptide of bovine β-casein is transported through Caco-2 monolayer
Daniela Regazzo et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2010)
Ala-Val-Phe and Val-Phe: ACE inhibitory peptides derived from insect protein with antihypertensive activity in spontaneously hypertensive rats
Lieselot Vercruysse et al.
PEPTIDES (2010)
Purification and Characterization of an Angiotensin I -converting Enzyme Inhibitory Peptide Derived From Spirulina platensis
Lu Jun et al.
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS (2010)
Angiotensin Converting Enzyme (ACE) Inhibitory Peptides: Production and Implementation of Functional Food
F. De Leo et al.
CURRENT PHARMACEUTICAL DESIGN (2009)
Study of the mechanism of antihypertensive peptides VPP and IPP in spontaneously hypertensive rats by DNA microarray analysis
Naoya Yamaguchi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Expression of testicular angiotensin-converting enzyme in adult spontaneously hypertensive rats
Nina Atanassova et al.
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2009)
Isolation and characterisation of a novel angiotensin I-converting enzyme (ACE) inhibitory peptide from the algae protein waste
I-Chuan Sheih et al.
FOOD CHEMISTRY (2009)
Novel casein-derived peptides with antihypertensive activity
Maria del Mar Contreras et al.
INTERNATIONAL DAIRY JOURNAL (2009)
Casein-derived bioactive peptides: Biological effects, industrial uses, safety aspects and regulatory status
Martha Phelan et al.
INTERNATIONAL DAIRY JOURNAL (2009)
Angiotensin I Converting Enzyme Inhibitory Peptides from Simulated in Vitro Gastrointestinal Digestion of Cooked Eggs
Kaustav Majumder et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)
Modeling of the Relationship between Dipeptide Structure and Dipeptide Stability, Permeability, and ACE Inhibitory Activity
Martin Foltz et al.
JOURNAL OF FOOD SCIENCE (2009)
Studies on the molecular recognition between bioactive peptides and angiotensin-converting enzyme
A. S. Pina et al.
JOURNAL OF MOLECULAR RECOGNITION (2009)
Purification and identification of an angiotensin I-converting enzyme inhibitory peptide from fermented soybean extract
Shin Joung Rho et al.
PROCESS BIOCHEMISTRY (2009)
Kinetics of the inhibition of renin and angiotensin I-converting enzyme by flaxseed protein hydrolysate fractions
Chibuike C. Udenigwe et al.
JOURNAL OF FUNCTIONAL FOODS (2009)
Purification of angiotensin I-converting enzyme-inhibitory peptides from the enzymatic hydrolysate of defatted canola meal
Jianping Wu et al.
FOOD CHEMISTRY (2008)
Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo
Sebastien Fuchs et al.
HYPERTENSION (2008)
Bioavailability of the antihypertensive peptide LHLPLP:: Transepithelial flux of HLPLP
Ana Quiros et al.
INTERNATIONAL DAIRY JOURNAL (2008)
Transport of Val-Leu-Pro-Val-Pro in human intestinal epithelial (Caco-2) cell monolayers
Lin Lei et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)
Producibility and digestibility of antihypertensive β-casein tripeptides, Val-Pro-Pro and Ile-Pro-Pro, in the gastrointestinal tract:: Analyses using an in vitro model of mammalian gastrointestinal digestion
Kazuhito Ohsawa et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)
Transepithelial transport across Caco-2 cell monolayers of antihypertensive egg-derived peptides. PepT1-mediated flux of Tyr-Pro-lle
Marta Miguel et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2008)
The angiotensin converting enzyme inhibitory tripeptides Ile-Pro-Pro and Val-Pro-Pro show increasing permeabilities with increasing physiological relevance of absorption models
Martin Foltz et al.
PEPTIDES (2008)
Met-Arg-Trp derived from Rubisco lowers blood pressure via prostaglandin D-2-dependent vasorelaxation in spontaneously hypertensive rats
Hui Zhao et al.
PEPTIDES (2008)
The antihypertensive effect of peptides: A novel alternative to drugs?
Fang Hong et al.
PEPTIDES (2008)
Identification of ACE-inhibitory peptides in salt-free soy sauce that are transportable across caco-2 cell monolayers
Xiao-Lin Zhu et al.
PEPTIDES (2008)
Angiotensin-I converting enzyme inhibitory peptide derived from porcine skeletal muscle myosin and its antihypertensive activity in spontaneously hypertensive rats
K. Katayama et al.
JOURNAL OF FOOD SCIENCE (2007)
High-level expression of milk-derived antihypertensive peptide in Escherichia coli and its bioactivity
Dong Liu et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2007)
Angiotensin-I converting enzyme inhibitory activity of coffee melanoidins
Jose A. Rufian-Henares et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2007)
Modelling relationship between angiotensin-(I)-converting enzyme inhibition and the bitter taste of peptides
Are Hugo Pripp et al.
FOOD CHEMISTRY (2007)
The use of high hydrostatic pressure to promote the proteolysis and release of bioactive peptides from ovalbumin
Ana Quiros et al.
FOOD CHEMISTRY (2007)
Value-added utilization of yak milk casein for the production of angiotensin-I-converting enzyme inhibitory peptides
Xue-Ying Mao et al.
FOOD CHEMISTRY (2007)
Quantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity
Jianping Wu et al.
JOURNAL OF PEPTIDE SCIENCE (2007)
Quantitative structure-activity relationship study of bitter peptides
Hyun-Ock Kim et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)
Physiological, chemical and technological aspects of milk-protein-derived peptides with antihypertensive and ACE-inhibitory activity
R. Lopez-Fandino et al.
INTERNATIONAL DAIRY JOURNAL (2006)
Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design
HR Corradi et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Changes in chymotrypsin hydrolysis of β-lactoglobulin A induced by high hydrostatic pressure
R Chicón et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)
Enzymatic debittering of food protein hydrolysates
RJ FitzGerald et al.
BIOTECHNOLOGY ADVANCES (2006)
Effect of simulated gastrointestinal digestion on the antihypertensive properties of ACE-inhibitory peptides derived from ovalbumin
M Miguel et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)
Structural requirements of angiotensin I-converting enzyme inhibitory peptides: Quantitative structure-activity relationship study of di- and tripeptides
JP Wu et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)
Quantification of ACE inhibiting peptides in human plasma using high performance liquid chromatography-mass spectrometry
CJ van Platerink et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2006)
Angiotensin I-converting enzyme inhibitor derived from soy protein hydrolysate and produced by using membrane reactor
WD Chiang et al.
FOOD CHEMISTRY (2006)
The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity
ZL Woodman et al.
BIOCHEMICAL JOURNAL (2005)
Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium
N Salamat-Miller et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2005)
Purification and identification of angiotensin converting enzyme inhibitory peptides from beef hydrolysates
A Jang et al.
MEAT SCIENCE (2005)
Kinetics of peptide fraction release during in vitro digestion of casein
RA Agudelo et al.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2004)
Bioavailability of angiotensin I converting enzyme inhibitory peptides
V Vermeirssen et al.
BRITISH JOURNAL OF NUTRITION (2004)
Assessment of prediction confidence and domain extrapolation of two structure-activity relationship models for predicting estrogen receptor binding activity
WD Tong et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2004)
Angiotensin converting enzyme-inhibitory activity of peptides isolated from Manchego cheese. Stability under simulated gastrointestinal digestion
JAG Ruiz et al.
INTERNATIONAL DAIRY JOURNAL (2004)
Angiotensin-converting enzyme-2: a molecular and cellular perspective
FJ Warner et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2004)
ACE-inhibitory activity and structural properties of peptide Asp-Lys-Ile-His-Pro [β-CN f(47-51)].: Study of the peptide forms synthesized by different methods
JA Gómez-Ruiz et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)
Evidence for the negative cooperativity of the two active sites within bovine somatic angiotensin-converting enzyme
PV Binevski et al.
FEBS LETTERS (2003)
Isolation and antihypertensive effect of angiotensin I-converting enzyme (ACE) inhibitory peptides from spinach Rubisco
YJ Yang et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2003)
Roles of the two active sites of somatic angiotensin-converting enzyme in the cleavage of angiotensin I and bradykinin - Insights from selective inhibitors
D Georgiadis et al.
CIRCULATION RESEARCH (2003)
New antihypertensive peptides isolated from rapeseed
ED Marczak et al.
PEPTIDES (2003)
Expression of milk-derived antihypertensive peptide in Escherichia coli
GS Lv et al.
JOURNAL OF DAIRY SCIENCE (2003)
The angiotensin converting enzyme (ACE)
D Coates
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2003)
Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
R Natesh et al.
NATURE (2003)
Angiotensin-I-converting enzyme and its relatives
JF Riordan
GENOME BIOLOGY (2003)
Absorption of Val-Tyr with in vitro angiotensin I-converting enzyme inhibitory activity into the circulating blood system of mild hypertensive subjects
T Matsui et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2002)
The angiotensin-converting enzyme gene family: genomics and pharmacology
AJ Turner et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2002)
Polyphenol/peptide binding and precipitation
AJ Charlton et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2002)
Effect of long-term intake of milk products on blood pressure in hypertensive rats
M Sipola et al.
JOURNAL OF DAIRY RESEARCH (2002)
Transepithelial transport of the bioactive tripeptide, Val-Pro-Pro, in human intestinal Caco-2 cell monolayers
M Satake et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2002)
Val-Tyr as a natural antihypertensive dipeptide can be absorbed into the human circulatory blood system
T Matsui et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2002)
Intestinal transport of the lactokinin Ala-Leu-Pro-Met-His-Ile-Arg through a Caco-2 Bbe monolayer
V Vermeirssen et al.
JOURNAL OF PEPTIDE SCIENCE (2002)
Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line
CU Nielsen et al.
JOURNAL OF CONTROLLED RELEASE (2001)
Identification of antihypertensive peptides from peptic digest of two microalgae, Chlorella vulgaris and Spirulina platensis
K Suetsuna et al.
MARINE BIOTECHNOLOGY (2001)
Purification and characterization of angiotensin I converting enzyme (ACE) inhibitory peptides from Alaska pollack (Theragra chalcogramma) skin
HG Byun et al.
PROCESS BIOCHEMISTRY (2001)
Angiotensin I converting enzyme inhibitory peptides purified from bovine skin gelatin hydrolysate
SK Kim et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2001)
A rapid screening system to determine drug affinities for the intestinal dipeptide transporter 2: affinities of ACE inhibitors
VA Moore et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2000)