4.6 Editorial Material

Multiple Myeloma Presenting as Disseminated Osteoblastic Lesions With Intense 18F-FDG Uptake on PET/CT

期刊

CLINICAL NUCLEAR MEDICINE
卷 46, 期 10, 页码 E492-E495

出版社

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLU.0000000000003542

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F-18-FDG PET/CT; multiple myeloma; osteosclerotic myeloma

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A 42-year-old woman presented with numbness and weakness in the lower limbs, and was diagnosed with multiple myeloma after examination, requiring further treatment.
A 42-year-old woman presented with numbness and weakness in the lower limbs. The radiograph, MRI, and Tc-99m-MDP bone scintigraphy revealed multiple bone lesions. The lesions were sclerotic on radiograph. Subsequent F-18-FDG PET/CT showed the lesions were disseminated and had intense F-18-FDG uptake. Monoclonal lambda plasmacytoma was confirmed after CT-guided biopsy of the third lumbar vertebral lesion. The laboratory data also showed a monoclonal immunoglobulin G lambda protein in serum and urine immunofixation. The patient was diagnosed as multiple myeloma finally. Multiple myeloma should be in the differential diagnosis scope of multiple osteoblastic lesions with intense F-18-FDG uptake on PET/CT.

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