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Hai Pham The et al.
MOLECULAR INFORMATICS (2011)
The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter
Sita D. Modali et al.
MOLECULAR MICROBIOLOGY (2011)
Evaluation of Multidrug Efflux Pump Inhibitors by a New Method Using Microfluidic Channels
Yoshimi Matsumoto et al.
PLOS ONE (2011)
Altered Antibiotic Transport in OmpC Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. coli
Hubing Lou et al.
PLOS ONE (2011)
Structures of sequential open states in a symmetrical opening transition of the TolC exit duct
Xue-Yuan Pei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mechanism and function of the outer membrane channel TolC in multidrug resistance and physiology of enterobacteria
Helen I. Zgurskaya et al.
FRONTIERS IN MICROBIOLOGY (2011)
Optimized Nile Red Efflux Assay of AcrAB-TolC Multidrug Efflux System Shows Competition between Substrates
Juegen A. Bohnert et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Kinetic Parameters of Efflux of Penicillins by the Multidrug Efflux Transporter AcrAB-TolC of Escherichia coli
Siew Ping Lim et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Nanoscale analysis of supported lipid bilayers using atomic force microscopy
Karim El Kirat et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)
Comparing the Temperature-Dependent Conductance of the Two Structurally Similar E. coli Porins OmpC and OmpF
Istvan Biro et al.
BIOPHYSICAL JOURNAL (2010)
Polymyxins and their novel derivatives
Martti Vaara
CURRENT OPINION IN MICROBIOLOGY (2010)
A flexible cation binding site in the multidrug major facilitator superfamily transporter LmrP is associated with variable proton coupling
Theresia A. Schaedler et al.
FASEB JOURNAL (2010)
Assessment of the activity of RND-type multidrug efflux pumps in Pseudomonas aeruginosa using tetraphenylphosphonium ions
Rimantas Daugelavicius et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2010)
TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium
Tsukasa Horiyama et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
A 96-well plate fluorescence assay for assessment of cellular permeability and active efflux in Salmonella enterica serovar Typhimurium and Escherichia coli
Nick G. Coldham et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
Extended-Connectivity Fingerprints
David Rogers et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)
Molecular Basis of Enrofloxacin Translocation through OmpF, an Outer Membrane Channel of Escherichia coli - When Binding Does Not Imply Translocation
Kozhinjampara R. Mahendran et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Molecular Simulations Reveal the Mechanism and the Determinants for Ampicillin Trans location through OmpF
Amit Kumar et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport
Feng Long et al.
NATURE (2010)
Coexistence of passive and carrier-mediated processes in drug transport
Kiyohiko Sugano et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems
Fabien De Angelis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Permeation of Antibiotics through Escherichia coli OmpF and OmpC Porins: Screening for Influx on a Single-Molecule Level
Kozhinjampara R. Mahendran et al.
JOURNAL OF BIOMOLECULAR SCREENING (2010)
Development of a liquid chromatography/mass spectrometry-based drug accumulation assay in Pseudomonas aeruginosa
Hongliang Cai et al.
ANALYTICAL BIOCHEMISTRY (2009)
Bacterial transporters: Charge translocation and mechanism
Constanta Ganea et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)
Structural and functional diversity of bacterial membrane fusion proteins
Helen I. Zgurskaya et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2009)
Role of TolC in Klebsiella oxytoca resistance to antibiotics
Anna Fenosa et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2009)
MacB ABC Transporter Is a Dimer Whose ATPase Activity and Macrolide-binding Capacity Are Regulated by the Membrane Fusion Protein MacA
Hong Ting Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Evidence for the Transport of Maltose by the Sucrose Permease, CscB, of Escherichia coli
Yang Peng et al.
JOURNAL OF MEMBRANE BIOLOGY (2009)
Structural Adaptations that Modulate Monosaccharide, Disaccharide, and Trisaccharide Specificities in Periplasmic Maltose-Binding Proteins
Matthew J. Cuneo et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Crystal Structure of the Membrane Fusion Protein CusB from Escherichia coli
Chih-Chia Su et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Analysis of Unstirred Water Layer in In Vitro Permeability Experiments
Timo Korjamo et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Kinetic behavior of the major multidrug efflux pump AcrB of Escherichia coli
Keiji Nagano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli
Laura Paixão et al.
Journal of Biological Engineering (2009)
Liposomes: Technologies and Analytical Applications
Aldo Jesorka et al.
ANNUAL REVIEW OF ANALYTICAL CHEMISTRY (2008)
Ins and Outs of Major Facilitator Superfamily, Antiporters
Christopher J. Law et al.
ANNUAL REVIEW OF MICROBIOLOGY (2008)
Characterization of TolC Efflux Pump Proteins from Pasteurella multocida
Tamas Hatfaludi et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Role of porins for uptake of antibiotics by Mycobacterium smegmatis
Olga Danilchanka et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug Resistance
Markus A. Seeger et al.
CURRENT DRUG TARGETS (2008)
Crystal structures of the OmpF porin: function in a colicin translocon
Eiki Yamashita et al.
EMBO JOURNAL (2008)
MacAB Is Involved in the Secretion of Escherichia coli Heat-Stable Enterotoxin II
Hiroyasu Yamanaka et al.
JOURNAL OF BACTERIOLOGY (2008)
Estimation of ADME properties in drug discovery:: Predicting Caco-2 cell permeability using atom-based stochastic and non-stochastic linear indices
Juan A. Castillo-Garit et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Facilitated permeation of antibiotics across membrane channels - Interaction of the quinolone moxifloxacin with the OmpF channel
Tivadar Mach et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Rapid screening of membrane protein activity: electrophysiological analysis of OmpF reconstituted in proteoliposomes
Mohamed Kreir et al.
LAB ON A CHIP (2008)
Assembly and channel opening in a bacterial drug efflux machine
Vassiliy N. Bavro et al.
MOLECULAR CELL (2008)
Atomic force microscopy of supported lipid bilayers
Marie-Paule Mingeot-Leclercq et al.
NATURE PROTOCOLS (2008)
Membrane lipids: where they are and how they behave
Gerrit van Meer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Structure, function, and evolution of bacterial ATP-binding cassette systems
Amy L. Davidson et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2008)
Quantitative visualization of passive transport across bilayer lipid membranes
John M. A. Grime et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Flexibility in the ABC transporter MsbA: Alternating access with a twist
Andrew Ward et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Crystal structure of a catalytic intermediate of the maltose transporter
Michael L. Oldham et al.
NATURE (2007)
Biomimetic tethered lipid membranes designed for membrane-protein interaction studies
Claire Rossi et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2007)
Kinetic evidence is consistent with the rocker-switch mechanism of membrane transport by GlpT
Christopher J. Law et al.
BIOCHEMISTRY (2007)
Structural determination of wild-type lactose permease
Lan Guan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Reconstitution of the Escherichia coli macrolide transporter:: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB
Elena B. Tikhonova et al.
MOLECULAR MICROBIOLOGY (2007)
Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers
Ina Hubatsch et al.
NATURE PROTOCOLS (2007)
Crystal structure of osmoporin OmpC from E-coli at 2.0 Å
Arnaud Basle et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
To see or not to see: Lateral organization of biological membranes and fluorescence microscopy
Luis A. Bagatolli
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
Channel activity of OmpF monitored in nano-BLMs
Eva K. Schmitt et al.
BIOPHYSICAL JOURNAL (2006)
Tigecycline: A glycylcycline antimicrobial agent
Thien-Ly Doan et al.
CLINICAL THERAPEUTICS (2006)
Targeting multidrug resistance in cancer
G Szakács et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Interaction of zwitterionic penicillins with the OmpF channel facilitates their translocation
C Danelon et al.
BIOPHYSICAL JOURNAL (2006)
Drug-lipid a interactions on the Escherichia coli ABC transporter MsbA
B Woebking et al.
JOURNAL OF BACTERIOLOGY (2005)
Photocurrents generated by bacteriorhodopsin adsorbed on nano-black lipid membranes
C Horn et al.
BIOPHYSICAL JOURNAL (2005)
Bacterial resistance to antibiotics: Enzymatic degradation and modification
GD Wright
ADVANCED DRUG DELIVERY REVIEWS (2005)
Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pKaflux method
A Avdeef et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Aminoglycosides are captured from both periplasm and cytoplasm by the AcrD multidrug efflux transporter of Escherichia coli
JR Aires et al.
JOURNAL OF BACTERIOLOGY (2005)
PAMPA -: a drug absorption in vitro model 7.: Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones
M Bermejo et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
In vitro synthesis of fully functional EmrE, a multidrug transporter, and study of its oligomeric state
Y Elbaz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The ATP switch model for ABC transporters
CF Higgins et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Alkalitolerance: A biological function for a multidrug transporter in pH homeostasis
O Lewinson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Drug permeation in biomembranes in vitro and in silico prediction and influence of physicochemical properties
A Mälkiä et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
Salting out the ionic selectivity of a wide channel: The asymmetry of OmpF
A Alcaraz et al.
BIOPHYSICAL JOURNAL (2004)
Channel activity of a viral transmembrane peptide in micro-BLMs:: Vpu1-32 from HIV-1
W Römer et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Efflux-mediated drug resistance in bacteria
XZ Li et al.
DRUGS (2004)
Omp35, a new Enterobacter aerogenes porin involved in selective susceptibility to cephalosporins
C Bornet et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Adaptation of Escherichia coli O157:H7 to pH alters membrane lipid composition, verotoxin secretion, and resistance to simulated gastric fluid acid
HG Yuk et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
Role of Klebsiella pneumoniae OmpK35 porin in antimicrobial resistance
A Doménech-Sánchez et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Paracellular and passive transcellular permeability in immortalized human corneal epithelial cell culture model
E Toropainen et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
Epidermal cell culture model derived from rat keratinocytes with permeability characteristics comparable to human cadaver skin
TM Suhonen et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
Size-dependent diffusion in the n-alkanes
BA Kowert et al.
JOURNAL OF PHYSICAL CHEMISTRY A (2003)
Aromatic stacking in the sugar binding site of the lactose permease
L Guan et al.
BIOCHEMISTRY (2003)
Recent advances in the prediction of blood-brain partitioning from molecular structure
M Lobell et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
PAMPA - a drug absorption in vitro model 5. Unstirred water layer in iso-pH mapping assays and pK(a)(flux) - optimized design (pOD-PAMPA)
JA Ruell et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2003)
Residue ionization and ion transport through OmpF channels
EM Nestorovich et al.
BIOPHYSICAL JOURNAL (2003)
Molecular basis of bacterial outer membrane permeability revisited
H Nikaido
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2003)
On the mechanism of substrate specificity by resistance nodulation division (RND)-type multidrug resistance pumps:: the large periplasmic loops of MexD from Pseudomonas aeruginosa are involved in substrate recognition
WM Mao et al.
MOLECULAR MICROBIOLOGY (2002)
Crystal structure of bacterial multidrug efflux transporter AcrB
S Murakami et al.
NATURE (2002)
A tetrameric porin limits the cell wall permeability of Mycobacterium smegmatis
H Engelhardt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Diffusion through channel derivatives of the Escherichia coli FhuA transport protein
M Braun et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Mechanistic parallels in bacterial and human multidrug efflux transporters
HI Zgurskaya et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2002)
Ion permeation and selectivity of OmpF porin: A theoretical study based on molecular dynamics, brownian dynamics, and continuum electrodiffusion theory
W Im et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Orientation and interactions of dipolar molecules during transport through OmpF porin
KM Robertson et al.
FEBS LETTERS (2002)
Method for estimation of low outer membrane permeability to β-lactam antibiotics
B Lakaye et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Designed to penetrate: Time-resolved interaction of single antibiotic molecules with bacterial pores
EM Nestorovich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
A comparative study of artificial membrane permeability assay for high throughput profiling of drug absorption potential
CY Zhu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2002)
Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and multidrug resistance-associated protein 2 (MRP2/ABCC2)
M Sasaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Transport of maltodextrins through maltoporin: A single-channel study
L Kullman et al.
BIOPHYSICAL JOURNAL (2002)
NorA functions as a multidrug efflux protein in both cytoplasmic membrane vesicles and reconstituted proteoliposomes
JL Yu et al.
JOURNAL OF BACTERIOLOGY (2002)
Molecular basis of voltage gating of OmpF porin
KM Robertson et al.
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE (2002)
Drug absorption in vitro model:: filter-immobilized artificial membranes 2.: Studies of the permeability properties of lactones in Piper methysticum Forst
A Avdeef et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2001)
Novel macrolide-specific ABC-type efflux transporter in Escherichia coli
N Kobayashi et al.
JOURNAL OF BACTERIOLOGY (2001)
Facilitated substrate transport through membrane proteins
C Hilty et al.
PHYSICAL REVIEW LETTERS (2001)
Role of charged residues at the OmpF porin channel constriction probed by mutagenesis and simulation
PS Phale et al.
BIOCHEMISTRY (2001)
Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes
MC Sulavik et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2001)
Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: Novel agents for combination therapy
O Lomovskaya et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2001)
Protein folding in the periplasm in the absence of primary oxidant DsbA: modulation of redox potential in periplasmic space via OmpL porin
C Dartigalongue et al.
EMBO JOURNAL (2000)
Microbial genome analyses: Comparative transport capabilities in eighteen prokaryotes
IT Paulsen et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Sugar transport through maltoporin of Escherichia coli -: Role of polar tracks
F Dumas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Interplay between efflux pumps may provide either additive or multiplicative effects on drug resistance
A Lee et al.
JOURNAL OF BACTERIOLOGY (2000)
Imipenem resistance of Enterobacter aerogenes mediated by outer membrane permeability
C Bornet et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2000)
Permeation of tetracyclines through membranes of liposomes and Escherichia coli
A Sigler et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
Specificity mutants of the binding protein of the oligopeptide transport system of Lactococcus lactis
A Picon et al.
JOURNAL OF BACTERIOLOGY (2000)
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