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Synthesis of cellulose aerogels as promising carriers for drug delivery: a review

期刊

CELLULOSE
卷 28, 期 5, 页码 2697-2714

出版社

SPRINGER
DOI: 10.1007/s10570-021-03734-9

关键词

Cellulose; Cellulose aerogels; Synthesis; Drug delivery carriers

资金

  1. National Natural Science Foundation of China [31971605]
  2. International Joint Research Center for Biomass Chemistry and Materials
  3. Shaanxi International Science and Technology Cooperation Base [2018GHJD-19]
  4. Shandong Key RD Program [2019JZZY010407, 2019JZZY010304]
  5. key scientific research plan (Key Laboratory) of Shaanxi Provincial Education Department [17JS016]
  6. Key Laboratory of Pulp and Paper Science and Technology of Ministry of Education/Shandong Province of China [KF201814]

向作者/读者索取更多资源

Cellulose aerogels, as an important raw material, have excellent biocompatibility and chemical functions, making it an ideal carrier for drug delivery with high porosity, large specific surface area, and ultra-light density. They can be used to improve bioavailability and drug loading, inspiring new research in intelligent drug delivery systems.
Cellulose is an important raw material used for the preparation of aerogel materials in life sciences. Cellulose aerogel's excellent biocompatibility, biodegradability, and nontoxicity combined with its multiple chemical functions make it an ideal carrier for drug delivery. Cellulose aerogels offer high porosity, large specific surface area, and ultra-light density. They can be used as drug carriers to improve bioavailability and drug loading. We reviewed the methods used to prepare cellulose aerogels with nanocellulose, renewable cellulose, and cellulose derivatives as raw materials. In addition, we described cellulose aerogels as a drug delivery carrier to inspire work in new drug delivery systems that intelligently use cellulose aerogels. Finally, we described the application prospects of intelligent and responsive cellulose aerogels in drug delivery systems.

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