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CANCER RESEARCH (2009)
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
Nahum Sonenberg et al.
CELL (2009)
Recombination Activator Function of the Novel RAD51-and RAD51B-binding Protein, Human EVL
Motoki Takaku et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
Carson C. Thoreen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
Maria Salazar et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034
Martin J. van den Bent et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Cell-type-specific isolation of ribosome-associated mRNA from complex tissues
Elisenda Sanz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
Nicholas T. Ingolia et al.
SCIENCE (2009)
Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
Morris E. Feldman et al.
PLOS BIOLOGY (2009)
Determinants of cerebrospinal fluid arsenic concentration in patients with acute promyelocytic leukemia on oral arsenic trioxide therapy
Wing-Yan Au et al.
BLOOD (2008)
Radiation-induced gene translation profiles reveal tumor type and cancer-specific components
Sandhya Kumaraswamy et al.
CANCER RESEARCH (2008)
Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types
Joseph P. Doyle et al.
CELL (2008)
A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types
Myriam Heiman et al.
CELL (2008)
Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated Raptor phosphorylation
Audrey Carriere et al.
CURRENT BIOLOGY (2008)
Regulation of arsenic trioxide-induced cellular responses by Mnk1 and Mnk2
Blazej Dolniak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture
Yirui Sun et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2
Ilya M. Terenin et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Malignant gliomas in adults
Patrick Y. Wen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Glial Progenitor-Like Phenotype in Low-Grade Glioma and Enhanced CD133-Expression and Neuronal Lineage Differentiation Potential in High-Grade Glioma
Johan Rebetz et al.
PLOS ONE (2008)
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
Andrew Y. Choo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma
E. Tchougounova et al.
ONCOGENE (2007)
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
Philippe P. Roux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements
Liana F. Lareau et al.
NATURE (2007)
Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-α involves activation of the MKK6/p38MAPK/MK2 cascade
Christian Ehlting et al.
JOURNAL OF IMMUNOLOGY (2007)
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma
Keith L. Ligon et al.
NEURON (2007)
The eukaryotic initiation factor-2 kinase pathway facilitates differential GADD45a expression in response to environmental stress
Hao-Yuan Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G
Nathan J. Moerke et al.
CELL (2007)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
Analysis of gene expression and chemoresistance of CDI33+ cancer stem cells in glioblastoma
Gentao Liu et al.
MOLECULAR CANCER (2006)
S6K1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
N. Valerio Dorrello et al.
SCIENCE (2006)
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
Shideng Bao et al.
CANCER RESEARCH (2006)
Adherent neural stem (NS) cells from fetal and adult forebrain
Steven M. Pollard et al.
CEREBRAL CORTEX (2006)
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
David Shahbazian et al.
EMBO JOURNAL (2006)
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Jeongwu Lee et al.
CANCER CELL (2006)
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
KE O'Reilly et al.
CANCER RESEARCH (2006)
Radiation-induced changes in gene expression involve recruitment of existing messenger RNAs to and away from polysomes.
X Lü et al.
CANCER RESEARCH (2006)
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
MK Holz et al.
CELL (2005)
INK4a/ARF:: A multifunctional tumor suppressor locus
NE Sharpless
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2005)
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
Y Zhu et al.
CANCER CELL (2005)
mTOR promotes urvival and astrocytic characteristics induced by Pten/Akt signaling in glioblastoma
XY Hu et al.
NEOPLASIA (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas
KL Ligon et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases
B Raught et al.
EMBO JOURNAL (2004)
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response
HY Jiang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
PP Roux et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
SJ Marciniak et al.
GENES & DEVELOPMENT (2004)
Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C
E Garcion et al.
DEVELOPMENT (2004)
Identification of human brain tumour initiating cells
SK Singh et al.
NATURE (2004)
Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation
N Fujiuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to Polysomes
VK Rajasekhar et al.
MOLECULAR CELL (2003)
Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2
J Kool et al.
ONCOGENE (2003)
SOCS3 negatively regulates IL-6 signaling in vivo
BA Croker et al.
NATURE IMMUNOLOGY (2003)
Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC
NG Ayad et al.
CELL (2003)
The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6
A Sasaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Modulation of the helicase activity of eIF4A by eIF4B, eIF4H, and eIF4F
GW Rogers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase
XM Wang et al.
EMBO JOURNAL (2001)
The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells
GC Scheper et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
EC Holland et al.
NATURE GENETICS (2000)
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