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Simvastatin Decreases Lipopolysaccharide-induced Pulmonary Inflammation in Healthy Volunteers
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Human neutrophils switch to an activated phenotype after homing to the lung irrespective of inflammatory disease
E. Fortunati et al.
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DARC on RBC limits lung injury by balancing compartmental distribution of CXC chemokines
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Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals
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Inescapable Need for Neutrophils as Mediators of Cellular Innate Immunity to Acute Pseudomonas aeruginosa Pneumonia
Andrew Y. Koh et al.
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JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling
Maria Rosaria Cera et al.
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Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection
Michelle D. Tate et al.
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Vav1 Is Essential for Mechanotactic Crawling and Migration of Neutrophils out of the Inflamed Microvasculature
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The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity
Monika Pruenster et al.
NATURE IMMUNOLOGY (2009)
Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player
Dietmar Vestweber et al.
TRENDS IN CELL BIOLOGY (2009)
p120-Catenin regulates leukocyte transmigration through an effect on VE-cadherin phosphorylation
Pilar Alcaide et al.
BLOOD (2008)
Endothelial CD47 interaction with SIRPγ is required for human T-cell transendothelial migration under shear flow conditions in vitro
Michael Stefanidakis et al.
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JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by α4β1 integrin activation
Anny-Claude Luissint et al.
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CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia
Xiao Su et al.
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Infiltrated Neutrophils Acquire Novel Chemokine Receptor Expression and Chemokine Responsiveness in Chronic Inflammatory Lung Diseases
Dominik Hart et al.
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The physiology of leukocyte recruitment: An in vivo perspective
Bjoern Petri et al.
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A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation
Amit Gaggar et al.
JOURNAL OF IMMUNOLOGY (2008)
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils
Bryan Heit et al.
NATURE IMMUNOLOGY (2008)
Endothelial Domes Encapsulate Adherent Neutrophils and Minimize Increases in Vascular Permeability in Paracellular and Transcellular Emigration
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PLOS ONE (2008)
Adhesion molecules involved in hepoxilin A3-mediated neutrophil transepithelial migration
B. P. Hurley et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2008)
Critical role of Mac-1 sialyl Lewis x moieties in regulating neutrophil degranulation and transmigration
Ke Zen et al.
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ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration
Michael J. Allingham et al.
JOURNAL OF IMMUNOLOGY (2007)
Adhesion and signaling molecules controlling the transmigration of leukocytes through endothelium
Dietmar Vestweber
IMMUNOLOGICAL REVIEWS (2007)
A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo
M. Gabriele Bixel et al.
BLOOD (2007)
Identification of an IL-17-producing NK1.1neg iNKT cell population involved in airway neutrophilia
Marie-Laure Michel et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Increased galectin-3 expression and intra-epithelial neutrophils in small airways in severe COPD
C. Pilette et al.
EUROPEAN RESPIRATORY JOURNAL (2007)
P-selectin glycoprotein ligand-1 is expressed on endothelial cells and mediates monocyte adhesion to activated endothelium
Paula da Costa Martins et al.
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Receptor for advanced glycation endproducts mediates neutrophil migration across intestinal epithelium
Ke Zen et al.
JOURNAL OF IMMUNOLOGY (2007)
A randomized, double-masked, placebo-controlled study of alicaforsen, an antisense inhibitor of intercellular adhesion molecule 1, for the treatment of subjects with active Crohn's disease
Bruce Yacyshyn et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2007)
Functions and regulation of NF-κB RelA during pneumococcal pneumonia
Lee J. Quinton et al.
JOURNAL OF IMMUNOLOGY (2007)
CD99 is a key mediator of the transendothelial migration of neutrophils
Olivia Lou et al.
JOURNAL OF IMMUNOLOGY (2007)
Getting to the site of inflammation: the leukocyte adhesion cascade updated
Klaus Ley et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation
Alexander Zarbock et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation
Janet S. Lee et al.
JOURNAL OF IMMUNOLOGY (2006)
Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade
Mia Phillipson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression
Amiram Ariel et al.
NATURE IMMUNOLOGY (2006)
Different susceptibilities of PECAM-deficient mouse strains to spontaneous idiopathic pneumonitis
Alan R. Schenkel et al.
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Alveolar epithelial cells direct monocyte transepithelial migration upon influenza virus infection: Impact of chemokines and adhesion molecules
Susanne Herold et al.
JOURNAL OF IMMUNOLOGY (2006)
ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability
Frank Wegmann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration
Miao-Tzu Huang et al.
BLOOD (2006)
Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils
Shijun Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis
J Rivera-Nieves et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
NM Weathington et al.
NATURE MEDICINE (2006)
Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung
J Reutershan et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells
N Demling et al.
CELL AND TISSUE RESEARCH (2006)
Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury
J Reutershan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)
Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses
LC Wang et al.
NATURE IMMUNOLOGY (2005)
Junctional adhesion molecule-A-deficient polyrnorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-α-activated vascular endothelium under flow
L Yang et al.
BLOOD (2005)
Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils
K Zen et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils
TS Walker et al.
INFECTION AND IMMUNITY (2005)
HIF-dependent induction of apical CD55 coordinates epithelial clearance of neutrophils
NA Louis et al.
FASEB JOURNAL (2005)
Induction of CXCL5 during inflammation in the rodent lung involves activation of alveolar epithelium
S Jeyaseelan et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2005)
Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation
M Aurrand-Lions et al.
JOURNAL OF IMMUNOLOGY (2005)
Neutrophil differentiated HL-60 cells model Mac-1 (CD11b/CD18)-independent neutrophil transepithelial migration
SO Carrigan et al.
IMMUNOLOGY (2005)
CD44 is a physiological E-selectin ligand on neutrophils
Y Katayama et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense
MB Fessler et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
Selective transport of cytokine-induced neutrophil chemoattractant from the lung to the blood facilitates pulmonary neutrophil recruitment
LJ Quinton et al.
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Receptor for advanced glycation end-products is a marker of type I lung alveolar cells
M Shirasawa et al.
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CLMP, a novel member of the CTX family and a new component of epithelial tight junctions
E Raschperger et al.
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Identification of genes differentially expressed in rat alveolar type I cells
K Dahlin et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2004)
JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration
K Zen et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
The junctional adhesion molecule-C promotes neutrophil transendothelial migration in vitro and in vivo
T Chavakis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Role of CD44 and hyaluronan in neutrophil recruitment
AI Khan et al.
JOURNAL OF IMMUNOLOGY (2004)
Respiratory epithelial cells regulate lung inflammation in response to inhaled endotoxin
SJ Skerrett et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Transcriptional profiling of lipopolysaccharide-induced acute lung injury
S Jeyaseelan et al.
INFECTION AND IMMUNITY (2004)
Platelet endothelial cell adhesion molecule deficiency or blockade significantly reduces leukocyte emigration in a majority of mouse strains
AR Schenkel et al.
JOURNAL OF IMMUNOLOGY (2004)
Mobilization of neutrophil sialidase activity desialylates the pulmonary vascular endothelial surface and increases resting neutrophil adhesion to and migration across the endothelium
S Sakarya et al.
GLYCOBIOLOGY (2004)
Polymorphonuclear cell transmigration induced by Pseudomonas aeruginosa requires the eicosanoid hepoxilin A3
BP Hurley et al.
JOURNAL OF IMMUNOLOGY (2004)
A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them
CV Carman et al.
JOURNAL OF CELL BIOLOGY (2004)
Identification of hepoxilin A3 in inflammatory events:: A required role in neutrophil migration across intestinal epithelia
RJ Mrsny et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Neutrophils migrate across intestinal epithelium using β2 integrin (CD11b/CD18)-independent mechanisms
KM Blake et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2004)
The tetraspan protein EMP2 modulates the surface expression of caveolins and glycosylphosphatidyl inositol-linked proteins
M Wadehra et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: A novel pathway for inflammatory cell recruitment
T Chavakis et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Antiadhesive role of apical decay-accelerating factor (CD55) in human neutrophil transmigration across mucosal epithelia
DW Lawrence et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Macrophage migration inhibitory factor: A regulator of innate immunity
T Calandra et al.
NATURE REVIEWS IMMUNOLOGY (2003)
Transepithelial migration of neutrophils in response to leukotriene B4 is mediated by a reactive oxygen species-extracellular signal-regulated kinase-linked cascade
CH Woo et al.
JOURNAL OF IMMUNOLOGY (2003)
A prominent role for airway epithelial NF-κB activation in lipopolysaccharide-induced airway inflammation
ME Poynter et al.
JOURNAL OF IMMUNOLOGY (2003)
Duffy antigen facilitates movement of chemokine across the endothelium in vitro and promotes neutrophil transmigration in vitro and in vivo
JS Lee et al.
JOURNAL OF IMMUNOLOGY (2003)
Cutting edge:: Roles of toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection
KI Happel et al.
JOURNAL OF IMMUNOLOGY (2003)
Unique structural features that influence neutrophil emigration into the lung
AR Burns et al.
PHYSIOLOGICAL REVIEWS (2003)
Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis
Z Mamdouh et al.
NATURE (2003)
Platelet endothelial cell adhesion molecule-1 in neutrophil emigration during acute bacterial pneumonia in mice and rats
S Tasaka et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2003)
CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in mice
Q Wang et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
CD11b/CD18-dependent interactions of neutrophils with intestinal epithelium are mediated by fucosylated proteoglycans
K Zen et al.
JOURNAL OF IMMUNOLOGY (2002)
The tetraspan protein epithelial membrane protein-2 interacts with β1 integrins and regulates adhesion
M Wadehra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients
B Heit et al.
JOURNAL OF CELL BIOLOGY (2002)
CD11b and intercellular adhesion molecule-1 are involved in pulmonary neutrophil recruitment in lipopolysaccharide-induced airway disease
JG Moreland et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's disease
BR Yacyshyn et al.
GUT (2002)
Very late antigen-4 in CD18-independent neutrophil emigration during acute bacterial pneumonia in mice
S Tasaka et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)
Signal regulatory protein (SIRPα), a cellular ligand for CD47, regulates neutrophil transmigration
Y Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Structural diversity of heparan sulfate binding domains in chemokines
H Lortat-Jacob et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes
G Ostermann et al.
NATURE IMMUNOLOGY (2002)
The role of CD47 in neutrophil transmigration - Increased rate of migration correlates with increased cell surface expression of CD47
Y Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense
P Ye et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Real-time imaging of vascular endothelial-cadherin during leukocyte transmigration across endothelium
SK Shaw et al.
JOURNAL OF IMMUNOLOGY (2001)
Targeted mutation of TNF receptor I rescues the ReIA-deficient mouse and reveals a critical role for NF-κB in leukocyte recruitment
E Alcamo et al.
JOURNAL OF IMMUNOLOGY (2001)
Negative regulation of epithelium-neutrophil interactions via activation of CD44
M Si-Tahar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2001)
Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation
VC Ridger et al.
JOURNAL OF IMMUNOLOGY (2001)
Impaired pulmonary host defense in mice lacking expression of the CXC chemokine Lungkine
SC Chen et al.
JOURNAL OF IMMUNOLOGY (2001)
Alveolar epithelial type II cell: defender of the alveolus revisited
H Fehrenbach
RESPIRATORY RESEARCH (2001)
Interleukin-8 and Leukotriene-B4, but not formylmethionyl leucylphenylalanine, stimulate CD18-independent migration of neutrophils across human pulmonary endothelial cells in vitro
AJ Mackarel et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2000)
Increased CD44 expression in human bronchial epithelial repair after damage or plating at low cell densities
SH Leir et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2000)
Cutting edge: Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes
A Bouchon et al.
JOURNAL OF IMMUNOLOGY (2000)
Neutrophil transmigration across human airway epithelial monolayers - Mechanisms and dependence on electrical resistance
JC Kidney et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2000)
Monocyte migration through the alveolar epithelial barrier: Adhesion molecule mechanisms and impact of chemokines
S Rosseau et al.
JOURNAL OF IMMUNOLOGY (2000)