When day meets night: Subsiding calcium signalling translates daylight into new neurones

Day/night cycle controls neurogenesis; melatonin released from pineal gland in darkness stimulates intracellular Ca2+ dynamics thus decreasing proliferation of neural stem cells. In the daylight intracellular Ca2+ activity subsides, which stimulates neural stem cells division and increases generation of newborn neurones.

Automated summary

The day/night cycle affects neurogenesis, with melatonin released in darkness decreasing neural stem cell proliferation by stimulating intracellular Ca2+ dynamics. During the day, neural stem cell division is stimulated and the generation of newborn neurons is increased as intracellular Ca2+ activity subsides.