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Oakley C. Olson et al.
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Xinbing Sui et al.
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Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry
E. C. Inwald et al.
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Solveigh C. Koeberle et al.
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Brian J. Altman et al.
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Noboru Mizushima et al.
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Zhi-Mei Lv et al.
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Mark P. LeGolvan et al.
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Congcong He et al.
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Cathepsin D: A cellular roadmap
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Vassiliki Karantza-Wadsworth et al.
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Ravi K. Amaravadi et al.
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Systems biology and combination therapy in the quest for clinical efficacy
Jonathan B. Fitzgerald et al.
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Kurt Degenhardt et al.
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S Miwatashi et al.
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The apoptosis/autophagy paradox:: autophagic vacuolization before apoptotic death
RA González-Polo et al.
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Breast cancer cells with inhibition of p38 alpha have decreased MMP-9 activity and exhibit decreased bone metastasis in mice
C Suarez-Cuervo et al.
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NA Bhowmick et al.
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TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
A Vassilev et al.
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