4.8 Article

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Kevin Bi et al.

Summary: The study shows that immune checkpoint blockade (ICB) remodels the RCC microenvironment and modifies the interplay between cancer and immune cell populations, critical for understanding response and resistance to ICB.

CANCER CELL (2021)

Article Biochemistry & Molecular Biology

VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium

Dmitry Bagaev et al.

NUCLEIC ACIDS RESEARCH (2020)

Article Multidisciplinary Sciences

Peripheral T cell expansion predicts tumour infiltration and clinical response

Thomas D. Wu et al.

NATURE (2020)

Article Multidisciplinary Sciences

Trajectory-based differential expression analysis for single-cell sequencing data

Koen Van den Berge et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

Lei Zhang et al.

Article Biochemistry & Molecular Biology

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Michal Slyper et al.

NATURE MEDICINE (2020)

Article Biotechnology & Applied Microbiology

Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows

Elena Denisenko et al.

GENOME BIOLOGY (2020)

Article Multidisciplinary Sciences

Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH

Chee-Huat Linus Eng et al.

NATURE (2019)

Article Multidisciplinary Sciences

Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution

Samuel G. Rodriques et al.

SCIENCE (2019)

Article Multidisciplinary Sciences

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan et al.

NATURE (2019)

Review Immunology

Cysteine Cathepsins in Tumor-Associated Immune Cells

Tanja Jakos et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Biochemistry & Molecular Biology

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma

David J. Clark et al.

Review Biochemistry & Molecular Biology

Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4

Shuang Qin et al.

MOLECULAR CANCER (2019)

Article Biochemistry & Molecular Biology

Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers

Wouter Scheper et al.

NATURE MEDICINE (2019)

Article Multidisciplinary Sciences

An intra-tumoral niche maintains and differentiates stem-like CD8 T cells

Caroline S. Jansen et al.

NATURE (2019)

Review Immunology

Macrophages as regulators of tumour immunity and immunotherapy

David G. DeNardo et al.

NATURE REVIEWS IMMUNOLOGY (2019)

Article Biochemistry & Molecular Biology

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

Mikhail Shugay et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biotechnology & Applied Microbiology

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

Kelly Street et al.

BMC GENOMICS (2018)

Article Biochemistry & Molecular Biology

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

Elham Azizi et al.

Article Biochemistry & Molecular Biology

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

Samra Turajlic et al.

Article Biochemistry & Molecular Biology

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

Samra Turajlic et al.

Article Biotechnology & Applied Microbiology

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

Laleh Haghverdi et al.

NATURE BIOTECHNOLOGY (2018)

Article Biotechnology & Applied Microbiology

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler et al.

NATURE BIOTECHNOLOGY (2018)

Review Biochemistry & Molecular Biology

Understanding the tumor immune microenvironment (TIME) for effective therapy

Mikhail Binnewies et al.

NATURE MEDICINE (2018)

Article Medicine, General & Internal

Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

R. J. Motzer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Cell Biology

T cell-induced CSF1 promotes melanoma resistance to PD1 blockade

Natalie J. Neubert et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

Article Biochemistry & Molecular Biology

Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging

Yury Goltsev et al.

Article Multidisciplinary Sciences

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

Matthew D. Young et al.

SCIENCE (2018)

Article Biochemistry & Molecular Biology

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma

Moshe Sade-Feldman et al.

Article Multidisciplinary Sciences

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer

Lei Zhang et al.

NATURE (2018)

Article Immunology

High Levels of Eomes Promote Exhaustion of Anti-tumor CD8+ T Cells

Jing Li et al.

FRONTIERS IN IMMUNOLOGY (2018)

Article Cell Biology

MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells

Ratna Sanyal et al.

IMMUNOLOGY AND CELL BIOLOGY (2017)

Letter Biochemical Research Methods

Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations

Susanne C. van den Brink et al.

NATURE METHODS (2017)

Review Oncology

The immune contexture in cancer prognosis and treatment

Wolf H. Fridman et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2017)

Article Multidisciplinary Sciences

Comprehensive analysis of normal adjacent to tumor transcriptomes

Dvir Aran et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing

Chunhong Zheng et al.

Article Biochemistry & Molecular Biology

An Immune Atlas of Clear Cell Renal Cell Carcinoma

Stephane Chevrier et al.

Article Biochemical Research Methods

Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R

Davis J. McCarthy et al.

BIOINFORMATICS (2017)

Article Biochemistry & Molecular Biology

A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells

Meromit Singer et al.

Article Biochemistry & Molecular Biology

ReactomePA: an R/Bioconductor package for reactome pathway analysis and visualization

Guangchuang Yu et al.

MOLECULAR BIOSYSTEMS (2016)

Article Multidisciplinary Sciences

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

Se Jin Im et al.

NATURE (2016)

Article Biotechnology & Applied Microbiology

Pooling across cells to normalize single-cell RNA sequencing data with many zero counts

Aaron T. L. Lun et al.

GENOME BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

Michael S. Rooney et al.

Article Biochemical Research Methods

FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data

Sofie Van Gassen et al.

CYTOMETRY PART A (2015)

Article Medicine, Research & Experimental

Selenoprotein P influences colitis-induced tumorigenesis by mediating stemness and oxidative damage

Caitlyn W. Barrett et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Review Biotechnology & Applied Microbiology

Combination cancer immunotherapy and new immunomodulatory targets

Kathleen M. Mahoney et al.

NATURE REVIEWS DRUG DISCOVERY (2015)

Article Microbiology

CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

Prakash K. Gupta et al.

PLoS Pathogens (2015)

Article Multidisciplinary Sciences

Discovery and saturation analysis of cancer genes across 21 tumour types

Michael S. Lawrence et al.

NATURE (2014)

Article Multidisciplinary Sciences

Comprehensivemolecular characterization of clear cell renal cell carcinoma

Chad J. Creighton et al.

NATURE (2013)

Article Genetics & Heredity

Pan-cancer patterns of somatic copy number alteration

Travis I. Zack et al.

NATURE GENETICS (2013)

Article Medicine, Research & Experimental

Macrophage plasticity and polarization: in vivo veritas

Antonio Sica et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Biotechnology & Applied Microbiology

Absolute quantification of somatic DNA alterations in human cancer

Scott L. Carter et al.

NATURE BIOTECHNOLOGY (2012)

Article Multidisciplinary Sciences

Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection

Michael A. Paley et al.

SCIENCE (2012)

Review Immunology

Transcriptional control of effector and memory CD8+ T cell differentiation

Susan M. Kaech et al.

NATURE REVIEWS IMMUNOLOGY (2012)

Article Biochemical Research Methods

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson et al.

BIOINFORMATICS (2010)

Article Biochemistry & Molecular Biology

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Aaron McKenna et al.

GENOME RESEARCH (2010)