4.6 Article

Oligosaccharides increase the genotoxic effect of colibactin produced by pks plus Escherichia coli strains

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Article Biotechnology & Applied Microbiology

Medicinal plant extracts protect epithelial cells from infection and DNA damage caused by colibactin-producingEscherichia coli, and inhibit the growth of bacteria

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Summary: The study found that extracts from Terminalia catappa, Psidium guajava, and Sandoricum koetjape can inhibit the growth and gene transcription of colibactin-producing Escherichia coli, as well as protect eukaryotic epithelial cells from infection and DNA damage. These plant extracts and compounds have the potential to protect against transient infections and DNA damage caused by E. coli carrying colibactin toxin.

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