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Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals
Peng Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Improving the production of human interferon gamma (hIFN-γ) in Pichia pastoris cell factory: An approach of cell level
Ashish A. Prabhu et al.
PROCESS BIOCHEMISTRY (2016)
Cloning and evaluation of different constitutive promoters in the oleaginous yeast Rhodosporidium toruloides
Yanan Wang et al.
YEAST (2016)
Enhancement of protein production via the strong DIT1 terminator and two RNA-binding proteins in Saccharomyces cerevisiae
Yoichiro Ito et al.
SCIENTIFIC REPORTS (2016)
Synthetic RNA Polymerase III Promoters Facilitate High-Efficiency CRISPR-Cas9-Mediated Genome Editing in Yarrowia lipolytica
Cory M. Schwartz et al.
ACS SYNTHETIC BIOLOGY (2016)
Expression and Purification of C-Peptide Containing Insulin Using Pichia pastoris Expression System
Mohammed N. Baeshen et al.
BIOMED RESEARCH INTERNATIONAL (2016)
High throughput, colorimetric screening of microbial ester biosynthesis reveals high ethyl acetate production from Kluyveromyces marxianus on C5, C6, and C12 carbon sources
Ann-Kathrin Lobs et al.
BIOTECHNOLOGY JOURNAL (2016)
Four Inducible Promoters for Controlled Gene Expression in the Oleaginous Yeast Rhodotorula toruloides
Alexander M. B. Johns et al.
FRONTIERS IN MICROBIOLOGY (2016)
Molecular optimization of rabies virus glycoprotein expression in Pichia pastoris
Safa Ben Azoun et al.
MICROBIAL BIOTECHNOLOGY (2016)
Integration and Validation of the Genome-Scale Metabolic Models of Pichia pastoris: A Comprehensive Update of Protein Glycosylation Pathways, Lipid and Energy Metabolism
Marius Tomas-Gamisans et al.
PLOS ONE (2016)
Differential RNA-seq, Multi-Network Analysis and Metabolic Regulation Analysis of Kluyveromyces marxianus Reveals a Compartmentalised Response to Xylose
Du Toit W. P. Schabort et al.
PLOS ONE (2016)
Synthetic and systems biology for microbial production of commodity chemicals
Victor Chubukov et al.
NPJ SYSTEMS BIOLOGY AND APPLICATIONS (2016)
Recent advances in bioengineering of the oleaginous yeast Yarrowia lipolytica
Murtaza Shabbir Hussain et al.
AIMS BIOENGINEERING (2016)
13C Metabolic Flux Analysis for Systematic Metabolic Engineering of S. cerevisiae for Overproduction of Fatty Acids
Amit Ghosh et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2016)
Yarrowia lipolytica: recent achievements in heterologous protein expression and pathway engineering
Catherine Madzak
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2015)
Engineering Scheffersomyces stipitis for fumaric acid production from xylose
Liang Wei et al.
BIORESOURCE TECHNOLOGY (2015)
Comprehensive Evaluation of Two Genome-Scale Metabolic Network Models for Scheffersomyces Stipitis
Andrew L. Damiani et al.
BIOTECHNOLOGY AND BIOENGINEERING (2015)
Evolved strains of Scheffersomyces stipitis achieving high ethanol productivity on acid- and base-pretreated biomass hydrolyzate at high solids loading
Patricia J. Slininger et al.
BIOTECHNOLOGY FOR BIOFUELS (2015)
Optimization of lipid production with a genome-scale model of Yarrowia lipolytica
Martin Kavscek et al.
BMC SYSTEMS BIOLOGY (2015)
Using Genome-scale Models to Predict Biological Capabilities
Edward J. O'Brien et al.
CELL (2015)
Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds
Jesse G. Zalatan et al.
CELL (2015)
Compact multi-enzyme pathways in P. pastoris
Martina Geier et al.
CHEMICAL COMMUNICATIONS (2015)
A roadmap for interpreting 13C metabolite labeling patterns from cells
Joerg M. Buescher et al.
CURRENT OPINION IN BIOTECHNOLOGY (2015)
Engineering metabolism through dynamic control
Naveen Venayak et al.
CURRENT OPINION IN BIOTECHNOLOGY (2015)
Computing the functional proteome: recent progress and future prospects for genome-scale models
Edward J. O'Brien et al.
CURRENT OPINION IN BIOTECHNOLOGY (2015)
Pichia pastoris as an expression host for membrane protein structural biology
Bernadette Byme
CURRENT OPINION IN STRUCTURAL BIOLOGY (2015)
Genome scale models of yeast: towards standardized evaluation and consistent omic integration
Benjamin J. Sanchez et al.
INTEGRATIVE BIOLOGY (2015)
Expression of enzymes for the usage in food and feed industry with Pichia pastoris
Sebastian C. Spohner et al.
JOURNAL OF BIOTECHNOLOGY (2015)
Deletion of hxk1 gene results in derepression of xylose utilization in Scheffersomyces stipitis
Mehdi Dashtban et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2015)
Compartmentalizing metabolic pathway in Candida glabrata for acetoin production
Shubo Li et al.
METABOLIC ENGINEERING (2015)
Engineering lipid overproduction in the oleaginous yeast Yarrowia lipolyticale
Kangjian Qiao et al.
METABOLIC ENGINEERING (2015)
Engineered CRISPR-Cas9 nucleases with altered PAM specificities
Benjamin P. Kleinstiver et al.
NATURE (2015)
Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition
Benjamin P. Kleinstiver et al.
NATURE BIOTECHNOLOGY (2015)
Reconstructing genome-scale metabolic models with merlin
Oscar Dias et al.
NUCLEIC ACIDS RESEARCH (2015)
SYNTHETIC BIOLOGY Complete biosynthesis of opioids in yeast
Stephanie Galanie et al.
SCIENCE (2015)
The development and characterization of synthetic minimal yeast promoters
Heidi Redden et al.
NATURE COMMUNICATIONS (2015)
A Highly Characterized Yeast Toolkit for Modular, Multipart Assembly
Michael E. Lee et al.
ACS SYNTHETIC BIOLOGY (2015)
A Method to Constrain Genome-Scale Models with 13C Labeling Data
Hector Garcia Martin et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
Comparative Analysis of Yeast Metabolic Network Models Highlights Progress, Opportunities for Metabolic Reconstruction
Benjamin D. Heavner et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
The Legacy of Nat Sternberg: The Genesis of Cre-lox Technology
Michael Yarmolinsky et al.
ANNUAL REVIEW OF VIROLOGY, VOL 2 (2015)
Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas
Andrew A. Horwitz et al.
CELL SYSTEMS (2015)
Use of Adaptive Laboratory Evolution To Discover Key Mutations Enabling Rapid Growth of Escherichia coli K-12 MG1655 on Glucose Minimal Medium
Ryan A. LaCroix et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2015)
Studies on the mechanism of synthesis of ethyl acetate in Kluyveromyces marxianus DSM 5422
Christian Loeser et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2015)
Engineering a cardosin B-derived rennet for sheep and goat cheese manufacture
Carla Malaquias Almeida et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2015)
Synthetic Protein Scaffolds Based on Peptide Motifs and Cognate Adaptor Domains for Improving Metabolic Productivity
Anselm H. C. Horn et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2015)
Flux Balance Analysis Inspired Bioprocess Upgrading for Lycopene Production by a Metabolically Engineered Strain of Yarrowia lipolytica
Komi Nambou et al.
METABOLITES (2015)
Engineering an efficient and tight D-amino acid-inducible gene expression system in Rhodosporidium/Rhodotorula species
Yanbin Liu et al.
MICROBIAL CELL FACTORIES (2015)
Metabolomics sampling of Pichia pastoris revisited: rapid filtration prevents metabolite loss during quenching
Hannes Russmayer et al.
FEMS YEAST RESEARCH (2015)
Metabolic network analysis and experimental study of lipid production in Rhodosporidium toruloides grown on single and mixed substrates
Rajesh Reddy Bommareddy et al.
MICROBIAL CELL FACTORIES (2015)
Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
Sangsu Bae et al.
BIOINFORMATICS (2014)
Dynamic Model-Based Analysis of Furfural and HMF Detoxification by Pure and Mixed Batch Cultures of S. cerevisiae and S. stipitis
Timothy J. Hanly et al.
BIOTECHNOLOGY AND BIOENGINEERING (2014)
iOD907, the first genome-scale metabolic model for the milk yeast Kluyveromyces lactis
Oscar Dias et al.
BIOTECHNOLOGY JOURNAL (2014)
Deletion of a KU80 homolog enhances homologous recombination in the thermotolerant yeast Kluyveromyces marxianus
Jin Ho Choo et al.
BIOTECHNOLOGY LETTERS (2014)
Probing the bioethanol production potential of Scheffersomyces (Pichia) stipitis using validated genome-scale model
Lisha K. Parambil et al.
BIOTECHNOLOGY LETTERS (2014)
Cre recombinase induces DNA damage and tetraploidy in the absence of LoxP sites
Vaibhao C. Janbandhu et al.
CELL CYCLE (2014)
Recent advances in the reconstruction of metabolic models and integration of omics data
Rajib Saha et al.
CURRENT OPINION IN BIOTECHNOLOGY (2014)
EasyClone: method for iterative chromosomal integration of multiple genes in Saccharomyces cerevisiae
Niels B. Jensen et al.
FEMS YEAST RESEARCH (2014)
Functional integration of multiple genes into the genome of the oleaginous yeast Rhodosporidium toruloides
Xinping Lin et al.
FEMS YEAST RESEARCH (2014)
The grammar of transcriptional regulation
Shira Weingarten-Gabbay et al.
HUMAN GENETICS (2014)
Impacts of high β-galactosidase expression on central metabolism of recombinant Pichia pastoris GS115 using glucose as sole carbon source via 13C metabolic flux analysis
Yongsheng Nie et al.
JOURNAL OF BIOTECHNOLOGY (2014)
A biosynthetic pathway for hexanoic acid production in Kluyveromyces marxianus
Yuna Cheon et al.
JOURNAL OF BIOTECHNOLOGY (2014)
Self- processing of ribozyme- flanked RNAs into guide RNAs in vitro and in vivo for CRISPR- mediated genome editing
Yangbin Gao et al.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY (2014)
Biopharmaceutical benchmarks 2014
Gary Walsh
NATURE BIOTECHNOLOGY (2014)
Constraint-based models predict metabolic and associated cellular functions
Aarash Bordbar et al.
NATURE REVIEWS GENETICS (2014)
Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris
Tamara Wriessnegger et al.
METABOLIC ENGINEERING (2014)
Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production
Justyna Nocon et al.
METABOLIC ENGINEERING (2014)
Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals
Weerawat Runguphan et al.
METABOLIC ENGINEERING (2014)
Kinetic models in industrial biotechnology - Improving cell factory performance
Joachim Almquist et al.
METABOLIC ENGINEERING (2014)
The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases
Ron Caspi et al.
NUCLEIC ACIDS RESEARCH (2014)
Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production
John Blazeck et al.
NATURE COMMUNICATIONS (2014)
k-OptForce: Integrating Kinetics with Flux Balance Analysis for Strain Design
Anupam Chowdhury et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
Generalizing a hybrid synthetic promoter approach in Yarrowia lipolytica
John Blazeck et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)
Characterization of glyceraldehyde-3-phosphate dehydrogenase gene RtGPD1 and development of genetic transformation method by dominant selection in oleaginous yeast Rhodosporidium toruloides
Yanbin Liu et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)
GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data
Brian J. Schmidt et al.
BIOINFORMATICS (2013)
Dynamic metabolic modeling of a microaerobic yeast co-culture: predicting and optimizing ethanol production from glucose/xylose mixtures
Timothy J. Hanly et al.
BIOTECHNOLOGY FOR BIOFUELS (2013)
Efficient homologous recombination with short length flanking fragments in Ku70 deficient Yarrowia lipolytica strains
Jonathan Verbeke et al.
BIOTECHNOLOGY LETTERS (2013)
Mapping condition-dependent regulation of metabolism in yeast through genome-scale modeling
Tobias Osterlund et al.
BMC SYSTEMS BIOLOGY (2013)
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert et al.
CELL (2013)
New opportunities by synthetic biology for biopharmaceutical production in Pichia pastoris
Thomas Vogl et al.
CURRENT OPINION IN BIOTECHNOLOGY (2013)
Frontiers of yeast metabolic engineering: diversifying beyond ethanol and Saccharomyces
Leqian Liu et al.
CURRENT OPINION IN BIOTECHNOLOGY (2013)
Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks
Yun Chen et al.
CURRENT OPINION IN BIOTECHNOLOGY (2013)
Metabolic engineering of yeast for production of fuels and chemicals
Jens Nielsen et al.
CURRENT OPINION IN BIOTECHNOLOGY (2013)
Formation of ethyl acetate from whey by Kluyveromyces marxianus on a pilot scale
Christian Loeser et al.
JOURNAL OF BIOTECHNOLOGY (2013)
Improved xylose fermentation of Kluyveromyces marxianus at elevated temperature through construction of a xylose isomerase pathway
Rongliang Wang et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2013)
Reconstruction and analysis of the genome-scale metabolic network of Candida glabrata
Nan Xu et al.
MOLECULAR BIOSYSTEMS (2013)
Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models
Emanuel Goncalves et al.
MOLECULAR BIOSYSTEMS (2013)
Analysis of omics data with genome-scale models of metabolism
Daniel R. Hyduke et al.
MOLECULAR BIOSYSTEMS (2013)
Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica
Zhixiong Xue et al.
NATURE BIOTECHNOLOGY (2013)
Cas9 as a versatile tool for engineering biology
Prashant Mali et al.
NATURE METHODS (2013)
Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production
Mitchell Tai et al.
METABOLIC ENGINEERING (2013)
Metabolic engineering of Kluyveromyces lactis for L-ascorbic acid (vitamin C) biosynthesis
Julio Cesar Camara Rosa et al.
MICROBIAL CELL FACTORIES (2013)
The RAVEN Toolbox and Its Use for Generating a Genome-scale Metabolic Model for Penicillium chrysogenum
Rasmus Agren et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Fifteen years of large scale metabolic modeling of yeast: Developments and impacts
Tobias Osterlund et al.
BIOTECHNOLOGY ADVANCES (2012)
Cloning and characterization of a panel of constitutive promoters for applications in pathway engineering in Saccharomyces cerevisiae
Jie Sun et al.
BIOTECHNOLOGY AND BIOENGINEERING (2012)
Controlling promoter strength and regulation in Saccharomyces cerevisiae using synthetic hybrid promoters
John Blazeck et al.
BIOTECHNOLOGY AND BIOENGINEERING (2012)
A constraint-based model of Scheffersomyces stipitis for improved ethanol production
Ting Liu et al.
BIOTECHNOLOGY FOR BIOFUELS (2012)
RNA-seq and microarray complement each other in transcriptome profiling
Sunitha Kogenaru et al.
BMC GENOMICS (2012)
Genome-scale metabolic model of the fission yeast Schizosaccharomyces pombe and the reconciliation of in silico/in vivo mutant growth
Seung Bum Sohn et al.
BMC SYSTEMS BIOLOGY (2012)
Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials
Luis Caspeta et al.
BMC SYSTEMS BIOLOGY (2012)
A genome-scale metabolic model of the lipid-accumulating yeast Yarrowia lipolytica
Nicolas Loira et al.
BMC SYSTEMS BIOLOGY (2012)
Construction of synthetic regulatory networks in yeast
Benjamin A. Blount et al.
FEBS LETTERS (2012)
Novel genetic tools for Hansenula polymorpha
Ruchi Saraya et al.
FEMS YEAST RESEARCH (2012)
Introduction and expression of genes for metabolic engineering applications in Saccharomyces cerevisiae
Nancy A. Da Silva et al.
FEMS YEAST RESEARCH (2012)
Development of quantitative metabolomics for Pichia pastoris
Marc Carnicer et al.
METABOLOMICS (2012)
Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose: methanol mixtures
Joel Jorda et al.
MICROBIAL CELL FACTORIES (2012)
Reconstruction and analysis of a genome-scale metabolic model for Scheffersomyces stipitis
Balaji Balagurunathan et al.
MICROBIAL CELL FACTORIES (2012)
Scheffersomyces stipitis: a comparative systems biology study with the Crabtree positive yeast Saccharomyces cerevisiae
Marta Papini et al.
MICROBIAL CELL FACTORIES (2012)
Customized optimization of metabolic pathways by combinatorial transcriptional engineering
Jing Du et al.
NUCLEIC ACIDS RESEARCH (2012)
Deletion of the Pichia pastoris KU70 Homologue Facilitates Platform Strain Generation for Gene Expression and Synthetic Biology
Laura Naeaetsaari et al.
PLOS ONE (2012)
Synthetic Biology and Metabolic Engineering
Gregory Stephanopoulos
ACS SYNTHETIC BIOLOGY (2012)
Prediction of Microbial Growth Rate versus Biomass Yield by a Metabolic Network with Kinetic Parameters
Roi Adadi et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
Tuning Gene Expression in Yarrowia lipolytica by a Hybrid Promoter Approach
John Blazeck et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)
Expanding a dynamic flux balance model of yeast fermentation to genome-scale
Felipe A. Vargas et al.
BMC SYSTEMS BIOLOGY (2011)
Dynamic flux balance analysis for pharmaceutical protein production by Pichia pastoris: Human growth hormone
Pinar Calik et al.
ENZYME AND MICROBIAL TECHNOLOGY (2011)
Disruption of PMR1 in Kluyveromyces lactis improves secretion of calf prochymosin
Zhen Feng et al.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2011)
Genome-Scale Consequences of Cofactor Balancing in Engineered Pentose Utilization Pathways in Saccharomyces cerevisiae
Amit Ghosh et al.
PLOS ONE (2011)
Metabolic Engineering for the Production of Natural Products
Lauren B. Pickens et al.
ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 2 (2011)
In Silico Identification of Gene Amplification Targets for Improvement of Lycopene Production
Hyung Seok Choi et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2010)
Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model
Keren Yizhak et al.
BIOINFORMATICS (2010)
iMAT: an integrative metabolic analysis tool
Hadas Zur et al.
BIOINFORMATICS (2010)
Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production
Seung Bum Sohn et al.
BIOTECHNOLOGY JOURNAL (2010)
A multi-level study of recombinant Pichia pastoris in different oxygen conditions
Kristin Baumann et al.
BMC SYSTEMS BIOLOGY (2010)
Post-translational modifications of protein biopharmaceuticals
Gary Walsh
DRUG DISCOVERY TODAY (2010)
Multiple-yapsin-deficient mutant strains for high-level production of intact recombinant proteins in Saccharomyces cerevisiae
Eun Young Cho et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Omic data from evolved E-coli are consistent with computed optimal growth from genome-scale models
Nathan E. Lewis et al.
MOLECULAR SYSTEMS BIOLOGY (2010)
What is flux balance analysis?
Jeffrey D. Orth et al.
NATURE BIOTECHNOLOGY (2010)
A protocol for generating a high-quality genome-scale metabolic reconstruction
Ines Thiele et al.
NATURE PROTOCOLS (2010)
Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement
Bevan K. S. Chung et al.
MICROBIAL CELL FACTORIES (2010)
Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis
Sriram Chandrasekaran et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Sampling the Solution Space in Genome-Scale Metabolic Networks Reveals Transcriptional Regulation in Key Enzymes
Sergio Bordel et al.
PLOS COMPUTATIONAL BIOLOGY (2010)
Kluyveromyces marxianus: A yeast emerging from its sister's shadow
Melanie M. Lane et al.
Fungal Biology Reviews (2010)
De Novo Biosynthesis of Vanillin in Fission Yeast (Schizosaccharomyces pombe) and Baker's Yeast (Saccharomyces cerevisiae)
Esben H. Hansen et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
High-level expression of non-glycosylated and active staphylokinase from Pichia pastoris
Anjali Apte-Deshpnade et al.
BIOTECHNOLOGY LETTERS (2009)
Flux balance analysis of biological systems: applications and challenges
Karthik Raman et al.
BRIEFINGS IN BIOINFORMATICS (2009)
Pichia stipitis genomics, transcriptomics, and gene clusters
Thomas W. Jeffries et al.
FEMS YEAST RESEARCH (2009)
Investigation of cellular targeting of carotenoid pathway enzymes in Pichia pastoris
Pyung Cheon Lee et al.
JOURNAL OF BIOTECHNOLOGY (2009)
Synthetic protein scaffolds provide modular control over metabolic flux
John E. Dueber et al.
NATURE BIOTECHNOLOGY (2009)
Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology
Pieter P. Jacobs et al.
NATURE PROTOCOLS (2009)
Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential?
Hal Alper et al.
NATURE REVIEWS MICROBIOLOGY (2009)
An Engineered Yeast Efficiently Secreting Penicillin
Loknath Gidijala et al.
PLOS ONE (2009)
Characterization of chromosomal integration sites for heterologous gene expression in Saccharomyces cerevisiae
Dongmei Bai Flagfeldt et al.
YEAST (2009)
Interpreting Expression Data with Metabolic Flux Models: Predicting Mycobacterium tuberculosis Mycolic Acid Production
Caroline Colijn et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Hypoxic fed-batch cultivation of Pichia pastoris increases specific and volumetric productivity of recombinant proteins
Kristin Baumann et al.
BIOTECHNOLOGY AND BIOENGINEERING (2008)
Cellulosic ethanol production using the naturally occurring xylose-fermenting yeast, Pichia stipitis
Frank K. Agbogbo et al.
BIOTECHNOLOGY LETTERS (2008)
Nonhomologous end joining and homologous recombination DNA repair pathways in integration mutagenesis in the xylose-fermenting yeast Pichia stipitis
Nicole Maassen et al.
FEMS YEAST RESEARCH (2008)
The transcriptional landscape of the yeast genome defined by RNA sequencing
Ugrappa Nagalakshmi et al.
SCIENCE (2008)
Analysis and characterization of hepatitis B vaccine particles synthesized from Hansenula polymorpha
Hyuk-Seong Seo et al.
VACCINE (2008)
Identification of the orotidine-5 '-monophosphate decarboxylase gene of the oleaginous yeast Rhodosporidium toruloides
Fan Yang et al.
YEAST (2008)
Context-specific metabolic networks are consistent with experiments
Scott A. Becker et al.
PLOS COMPUTATIONAL BIOLOGY (2008)
Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions
Evan S. Snitkin et al.
GENOME BIOLOGY (2008)
High-density cultivation of oleaginous yeast Rhodosporidium toruloides Y4 in fed-batch culture
Yonghong Li et al.
ENZYME AND MICROBIAL TECHNOLOGY (2007)
Application of the Cre-loxP system for multiple gene disruption in the yeast Kluyveromyces marxianus
Orquidea Ribeiro et al.
JOURNAL OF BIOTECHNOLOGY (2007)
Sorbitol co-feeding reduces metabolic burden caused by the overexpression of a Rhizopus oryzae lipase in Pichia pastoris
Ramon Ramon et al.
JOURNAL OF BIOTECHNOLOGY (2007)
Multiple high-throughput analyses monitor the response of E-coli to perturbations
Nobuyoshi Ishii et al.
SCIENCE (2007)
The nature of systems biology
Frank J. Bruggeman et al.
TRENDS IN MICROBIOLOGY (2007)
BRENDA, AMENDA and FRENDA: the enzyme information system in 2007
Jens Barthelmes et al.
NUCLEIC ACIDS RESEARCH (2007)
Metabolic flux profiling of Pichia pastoris grown on glycerol/methanol mixtures in chemostat cultures at low and high dilution rates
Aina Sola et al.
MICROBIOLOGY-SGM (2007)
Efficient production of L-lactic acid from xylose by Pichia stipitis
Maria Ilmen et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)
A synergistic effect on the production of S-adenosyl-L-methionine in Pichia pastoris by knocking in of S-adenosyl-L-methionine synthase and knocking out of cystathionine-β synthase
Junyun He et al.
JOURNAL OF BIOTECHNOLOGY (2006)
Humanization of yeast to produce complex terminally sialylated glycoproteins
Stephen R. Hamilton et al.
SCIENCE (2006)
An aqueous-organic two-phase bioprocess for efficient production of the natural aroma chemicals 2-phenylethanol and 2-phenylethylacetate with yeast
M. M. W. Etschmann et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2006)
Sh ble and Cre adapted for functional genomics and metabolic engineering of Pichia stipitis
JM Laplaza et al.
ENZYME AND MICROBIAL TECHNOLOGY (2006)
From genomics to chemical genomics: new developments in KEGG
Minoru Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2006)
Kluyveromyces lactis LAC4 promoter variants that lack function in bacteria but retain full function in K. lactis
PA Colussi et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)
Xylitol production by a Pichia stipitis D-xylulokinase mutant
YS Jin et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2005)
In vitro screening of probiotic properties of Saccharomyces cerevisiae var. boulardii and food-borne Saccharomyces cerevisiae strains
AVDA Kühle et al.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2005)
Heterologous protein production using the Pichia pastoris expression system
S Macauley-Patrick et al.
YEAST (2005)
Efficient gene targeting in Kluyveromyces lactis
R Kooistra et al.
YEAST (2004)
Genome-scale models of microbial cells: Evaluating the consequences of constraints
ND Price et al.
NATURE REVIEWS MICROBIOLOGY (2004)
Exploring the overproduction of amino acids using the bilevel optimization framework OptKnock
P Pharkya et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
OptKnock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization
AP Burgard et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
New disruption cassettes for rapid gene disruption and marker rescue in the yeast Yarrowia lipolytica
P Fickers et al.
JOURNAL OF MICROBIOLOGICAL METHODS (2003)
Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network
I Famili et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Advances in flux balance analysis
KJ Kauffman et al.
CURRENT OPINION IN BIOTECHNOLOGY (2003)
Modeling of yeast metabolism and process dynamics in batch fermentation
J Sainz et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network
J Förster et al.
GENOME RESEARCH (2003)
Analysis of optimality in natural and perturbed metabolic networks
D Segrè et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Transcriptional regulation in constraints-based metabolic models of Escherichia coli
MW Covert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of gene expression in flux balance models of metabolism
MW Covert et al.
JOURNAL OF THEORETICAL BIOLOGY (2001)
Synthesis of polyhydroxyalkanoate in the peroxisome of Saccharomyces cerevisiae by using intermediates of fatty acid β-oxidation
Y Poirier et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2001)
Plasmids with the Cre-recombinase and the dominant nat marker, suitable for use in prototrophic strains of Saccharomyces cerevisiae and Kluyveromyces lactis
HY Steensma et al.
YEAST (2001)
Only centromeres can supply the partition system required for ARS function in the yeast Yarrowia lipolytica
L Vernis et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
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