期刊
BIORESOURCE TECHNOLOGY
卷 321, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2020.124457
关键词
Anaerobic fermentation; Volatile fatty acids; Oleaginous microorganisms; Lipid accumulation; Omega-3 fatty acids
资金
- Swedish Research Council (FORMAS) [2018-00818]
Volatile fatty acids, generated during anaerobic digestion of organic waste, have emerged as a renewable feedstock for microbial oil production. This review discusses the metabolic pathways enabling lipogenesis from volatile fatty acids and strategies to enhance lipid accumulation by tuning the ratios of volatile fatty acids in oleaginous microorganisms.
To meet environmental sustainability goals, microbial oils have been suggested as an alternative to petroleum based products. At present, microbial fermentation for oil production relies on pure sugar-based feedstocks. However, these feedstocks are expensive and are in limited supply. Volatile fatty acids, which are generated as intermediates during anaerobic digestion of organic waste have emerged as a renewable feedstock that has the potential to replace conventional sugar sources for microbial oil production. They comprise short-chain (C2 to C6) organic acids and are employed as building blocks in the chemical industry. The present review discusses the use of oleaginous microorganisms for the production of biofuels and added-value products starting from volatile fatty acids as feedstocks. The review describes the metabolic pathways enabling lipogenesis from volatile fatty acids, and focuses on strategies to enhance lipid accumulation in oleaginous microorganisms by tuning the ratios of volatile fatty acids generated via anaerobic fermentation.
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