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microRNA-140: A miRNA with diverse roles in human diseases

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Summary: PM2.5, fine atmospheric particles, has a large specific surface area and carries various substances, posing a risk to human health. Through experiments on human bronchial epithelial cells (16HBE), it was found that the miR-140-5p/TLR4 signaling pathway may be involved in the inflammatory response induced by PM2.5.

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miR-140-5p targeted FGF9 and inhibited the cell growth of laryngeal squamous cell carcinoma

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MALAT1 knockdown inhibits prostate cancer progression by regulating miR-140/BIRC6 axis

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MiR-140 targets RAP2A to enable the proliferation of insulin-treated ovarian granulosa cells

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LncRNA HCP5 Regulates Pancreatic Cancer Progression by miR-140-5p/CDK8 Axis

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miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence

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miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer's Disease

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MiR-9-5p inhibits mitochondrial damage and oxidative stress in AD cell models by targeting GSK-3β

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The miR-140-5p/KLF9/KCNQ1 axis promotes the progression of renal cell carcinoma

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CircRNA SMARCC1 Sponges MiR-140-3p to Regulate Cell Progression in Colorectal Cancer

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The effects of miR-140-5p on the biological characteristics of ovarian cancer cells through the Wnt signaling pathway

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MiR-140 Resensitizes Cisplatin-Resistant NSCLC Cells to Cisplatin Treatment Through the SIRT1/ROS/JNK Pathway

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lncRNA MALAT1 potentiates the progression of tongue squamous cell carcinoma through regulating miR-140-5p-PAK1 pathway

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miR-140-5p induces cell apoptosis and decreases Warburg effect in chronic myeloid leukemia by targeting SIX1

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DNA methylation regulates miR-140-5p and miR-146a expression in osteoarthritis

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Amplification of lncRNA PVT1 promotes ovarian cancer proliferation by binding to miR-140

Yuqin Ding et al.

MAMMALIAN GENOME (2019)

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Role of autophagy in osteosarcoma

Olivier Camuzard et al.

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miR-140-3p Suppresses Cell Growth And Induces Apoptosis In Colorectal Cancer By Targeting PD-L1

Wei Jiang et al.

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Long noncoding RNA SNHG 16 induces sorafenib resistance in hepatocellular carcinoma cells through sponging miR-140-5p

Junfeng Ye et al.

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LncRNA SNHG20 promotes cell proliferation and invasion via miR-140-5p-ADAM10 axis in cervical cancer

Huimin Guo et al.

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MicroRNA-574-5p promotes cell growth of vascular smooth muscle cells in the progression of coronary artery disease

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MiR-140 Expression Regulates Cell Proliferation and Targets PD-L1 in NSCLC

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Regulation of ADAM10 by miR-140-5p and potential relevance for Alzheimer's disease

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MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer

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Dysregulation of KCNQ1OT1 promotes cholangiocarcinoma progression via miR-140-5p/SOX4 axis

Hongwei Sun et al.

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Long non-coding RNA SBF2-AS1 promotes hepatocellular carcinoma progression through regulation of miR-140-5p-TGFBR1 pathway

Yu Li et al.

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Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

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miR-140-5p suppresses retinoblastoma cell proliferation, migration, and invasion by targeting CEMIP and CADM3

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miR-140-5p suppresses the proliferation, migration and invasion of gastric cancer by regulating YES1

Zheng Fang et al.

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MicroRNA-140-5p regulates osteosarcoma chemoresistance by targeting HMGN5 and autophagy

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MiR-140-5p inhibits synovial fibroblasts proliferation and inflammatory cytokines secretion through targeting TLR4

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NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis

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