4.4 Review

Aging and age-related diseases: from mechanisms to therapeutic strategies

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Genetics & Heredity

Autophagy in aging and longevity

Shi Q. Wong et al.

HUMAN GENETICS (2020)

Article Endocrinology & Metabolism

Exercise Degrades Bone in Caloric Restriction, Despite Suppression of Marrow Adipose Tissue (MAT)

Cody McGrath et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2020)

Article Cell Biology

Cell senescence contributes to tissue regeneration in zebrafish

Sabela Da Silva-Alvarez et al.

AGING CELL (2020)

Review Cell Biology

Memory CD4(+) T Cells in Immunity and Autoimmune Diseases

Itay Raphael et al.

Review Allergy

Influence of immune aging on vaccine responses

Claire E. Gustafson et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Review Immunology

Targeting Inflammation and Immunosenescence to Improve Vaccine Responses in the Elderly

Branca Pereira et al.

FRONTIERS IN IMMUNOLOGY (2020)

Article Public, Environmental & Occupational Health

Medical crowdfunding in a healthcare system with universal coverage: an exploratory study

Agnes Lubloy

BMC PUBLIC HEALTH (2020)

Review Immunology

I mmunosenescence and Inflammaging: Risk Factors of Severe COVID-19 in Older People

Anna Julia Pietrobon et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Physiology

Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging

David A. Hood et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 81 (2019)

Review Biochemistry & Molecular Biology

Epigenetic changes during aging and their reprogramming potential

Alice E. Kane et al.

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2019)

Review Orthopedics

Regulatory mechanisms and clinical manifestations of musculoskeletal aging

Caleb Grote et al.

JOURNAL OF ORTHOPAEDIC RESEARCH (2019)

Editorial Material Cell Biology

Rapamycin and Alzheimer disease: a double-edged sword?

Julian M. Carosi et al.

AUTOPHAGY (2019)

Review Physiology

CELLULAR SENESCENCE: AGING, CANCER, AND INJURY

Arianna Calcinotto et al.

PHYSIOLOGICAL REVIEWS (2019)

Review Cell Biology

The Epigenetics of Stem Cell Aging Comes of Age

Danica Chen et al.

TRENDS IN CELL BIOLOGY (2019)

Article Physiology

Metformin Monotherapy Downregulates Diabetes-Associated Inflammatory Status and Impacts on Mortality

Anteneh Mehari Tizazu et al.

FRONTIERS IN PHYSIOLOGY (2019)

Review Endocrinology & Metabolism

Obesity May Accelerate the Aging Process

Valentina Salvestrini et al.

FRONTIERS IN ENDOCRINOLOGY (2019)

Review Multidisciplinary Sciences

From discoveries in ageing research to therapeutics for healthy ageing

Judith Campisi et al.

NATURE (2019)

Review Biotechnology & Applied Microbiology

Theories of Aging and the Prevalence of Alzheimer's Disease

Kaynara Trevisan et al.

BIOMED RESEARCH INTERNATIONAL (2019)

Review Genetics & Heredity

DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging

Vinod Tiwari et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2019)

Review Dermatology

Premature aging syndromes: From patients to mechanism

Mattheus Xing Rong Foo et al.

JOURNAL OF DERMATOLOGICAL SCIENCE (2019)

Article Biochemistry & Molecular Biology

HDAC1 and HDAC2 Double Knockout Triggers Cell Apoptosis in Advanced Thyroid Cancer

Ching-Ling Lin et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Geriatrics & Gerontology

Klotho Deficiency Accelerates Stem Cells Aging by Impairing Telomerase Activity

Mujib Ullah et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2019)

Review Clinical Neurology

Caloric restriction, longevity and aging: Recent contributions from human and non-human primate studies

Fabien Pifferi et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2019)

Article Medicine, General & Internal

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

Jamie N. Justice et al.

EBIOMEDICINE (2019)

Review Cell Biology

The telomere world and aging: Analytical challenges and future perspectives

Emanuela Mensa et al.

AGEING RESEARCH REVIEWS (2019)

Review Biochemistry & Molecular Biology

Senotherapeutics: emerging strategy for healthy aging and age-related disease

Eok-Cheon Kim et al.

BMB REPORTS (2019)

Review Oncology

Unmasking senescence: context-dependent effects of SASP in cancer

Douglas V. Faget et al.

NATURE REVIEWS CANCER (2019)

Review Cell Biology

Pathways of cellular proteostasis in aging and disease

Courtney L. Klaips et al.

JOURNAL OF CELL BIOLOGY (2018)

Review Cell Biology

Stem cells: Aging and transcriptional fingerprints

Brice E. Keyes et al.

JOURNAL OF CELL BIOLOGY (2018)

Article Endocrinology & Metabolism

Significant improvement in cardiometabolic health in healthy nonobese individuals during caloric restriction-induced weight loss and weight loss maintenance

Jasper Most et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2018)

Article Behavioral Sciences

Resveratrol promotes hUC-MSCs engraftment and neural repair in a mouse model of Alzheimer's disease

Xinxin Wang et al.

BEHAVIOURAL BRAIN RESEARCH (2018)

Editorial Material Biochemistry & Molecular Biology

Do-It-Yourself Calorie Restriction: The Risks of Simplistically Translating Findings in Animal Models to Humans

Eric Le Bourg et al.

BIOESSAYS (2018)

Review Medical Laboratory Technology

Telomere biology and age-related diseases

Markus Herrmann et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2018)

Article Immunology

Immune senescence, epigenetics and autoimmunity

Donna Ray et al.

CLINICAL IMMUNOLOGY (2018)

Article Endocrinology & Metabolism

Pharmacokinetics of metformin in patients with gastrointestinal intolerance

Laura J. McCreight et al.

DIABETES OBESITY & METABOLISM (2018)

Article Cell Biology

The senescent bystander effect is caused by ROS-activated NF-κB signalling

Glyn Nelsons et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2018)

Article Biotechnology & Applied Microbiology

Senotherapeutics for healthy ageing

Laura J. Niedernhofer et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

Editorial Material Endocrinology & Metabolism

Sustained caloric restriction in health

Ivone Leong

NATURE REVIEWS ENDOCRINOLOGY (2018)

Article Geriatrics & Gerontology

Muscle strength and size are associated with motor unit connectivity in aged mice

Kajri A. Sheth et al.

NEUROBIOLOGY OF AGING (2018)

Review Biochemistry & Molecular Biology

Resveratrol Boosts Cognitive Function by Targeting SIRT1

Wenyan Cao et al.

NEUROCHEMICAL RESEARCH (2018)

Review Pharmacology & Pharmacy

Effect of resveratrol on cognitive and memory performance and mood: A meta-analysis of 225 patients

Mohammad Hosein Farzaei et al.

PHARMACOLOGICAL RESEARCH (2018)

Review Biochemical Research Methods

Protein Turnover in Aging and Longevity

Nathan Basisty et al.

PROTEOMICS (2018)

Review Cell Biology

Hallmarks of Cellular Senescence

Alejandra Hernandez-Segura et al.

TRENDS IN CELL BIOLOGY (2018)

Article Multidisciplinary Sciences

A transcriptomic atlas of aged human microglia

Marta Olah et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration

Chao Xiong et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2018)

Review Biochemical Research Methods

Aging and the immune system: An overview

Amir A. Sadighi Akha

JOURNAL OF IMMUNOLOGICAL METHODS (2018)

Article Multidisciplinary Sciences

Mutations of mitochondrial DNA are not major contributors to aging of fruit flies

Timo E. S. Kauppila et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Biochemistry & Molecular Biology

Changes of Cell Biochemical States Are Revealed in Protein Homomeric Complex Dynamics

Bram Stynen et al.

Article Biochemistry & Molecular Biology

Combination of Berberine with Resveratrol Improves the Lipid-Lowering Efficacy

Xiaofei Zhu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Multidisciplinary Sciences

Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model

Karolina J. Janczura et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Biochemistry & Molecular Biology

Effect of resveratrol and pterostilbene on aging and longevity

Yi-Rong Li et al.

BIOFACTORS (2018)

Review Genetics & Heredity

FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process

Antero Salminen et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2017)

Review Immunology

Reactive Astrocytes: Production, Function, and Therapeutic Potential

Shane A. Liddelow et al.

IMMUNITY (2017)

Article Biochemistry & Molecular Biology

The Contribution of Oxidative Stress and Inflamm-Aging in Human and Equine Asthma

Michela Bullone et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Cardiac & Cardiovascular Systems

The Aging Cardiovascular System Understanding It at the Cellular and Clinical Levels

Francesco Paneni et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2017)

Article Multidisciplinary Sciences

Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

Vincenzo Sorrentino et al.

NATURE (2017)

Review Cell Biology

Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases

Nard Kubben et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Review Biotechnology & Applied Microbiology

The Business of Anti-Aging Science

Joao Pedro de Magalhaes et al.

TRENDS IN BIOTECHNOLOGY (2017)

News Item Endocrinology & Metabolism

American Diabetes Association Standards of Medical Care in Diabetes 2017

Payal H. Marathe et al.

JOURNAL OF DIABETES (2017)

Article Multidisciplinary Sciences

The effect of metformin on survival of patients with pancreatic cancer: a meta-analysis

Xiaogang Li et al.

SCIENTIFIC REPORTS (2017)

Review Pharmacology & Pharmacy

Neurogenesis in the aging brain

Deana M. Apple et al.

BIOCHEMICAL PHARMACOLOGY (2017)

Review Multidisciplinary Sciences

Effects of resveratrol on eNOS in the endothelium and the perivascular adipose tissue

Ning Xia et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2017)

Review Cell Biology

Dietary restriction and lifespan: Lessons from invertebrate models

Pankaj Kapahi et al.

AGEING RESEARCH REVIEWS (2017)

Article Biochemistry & Molecular Biology

Unmasking Transcriptional Heterogeneity in Senescent Cells

Alejandra Hernandez-Segura et al.

CURRENT BIOLOGY (2017)

Review Multidisciplinary Sciences

Resveratrol for Alzheimer's disease

Christine Sawda et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2017)

Review Cell Biology

Mammalian Mitochondria and Aging: An Update

Timo E. S. Kauppila et al.

CELL METABOLISM (2017)

Article Endocrinology & Metabolism

Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial

Dennis T. Villareal et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2016)

Article Biochemistry & Molecular Biology

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

Jianhui Chang et al.

NATURE MEDICINE (2016)

Review Cell Biology

A synopsis on aging-Theories, mechanisms and future prospects

Joao Pinto da Costa et al.

AGEING RESEARCH REVIEWS (2016)

Article Cell Biology

Metformin as a Tool to Target Aging

Nir Barzilai et al.

CELL METABOLISM (2016)

Article Cell Biology

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

Christopher D. Wiley et al.

CELL METABOLISM (2016)

Article Medicine, General & Internal

Comparison of Clinical Outcomes and Adverse Events Associated With Glucose-Lowering Drugs in Patients With Type 2 Diabetes A Meta-analysis

Suetonia C. Palmer et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

Article Endocrinology & Metabolism

Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study

Vanita R. Aroda et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)

Review Geriatrics & Gerontology

Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island

Sebastian I. Arriola Apelo et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2016)

Review Cell Biology

Balancing Inflammation: The Link between Th17 and Regulatory T Cells

Maggie L. Diller et al.

MEDIATORS OF INFLAMMATION (2016)

Article Biochemistry & Molecular Biology

Resveratrol Exerts Dosage-Dependent Effects on the Self-Renewal and Neural Differentiation of hUC-MSCs

Xinxin Wang et al.

MOLECULES AND CELLS (2016)

Article Multidisciplinary Sciences

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

Darren J. Baker et al.

NATURE (2016)

Article Behavioral Sciences

Protective effects of resveratrol on aging-induced cognitive impairment in rats

Serail Selcen Gocmez et al.

NEUROBIOLOGY OF LEARNING AND MEMORY (2016)

Review Cell Biology

Dietary Restriction and Nutrient Balance in Aging

Julia Santos et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Article Multidisciplinary Sciences

Senescent intimal foam cells are deleterious at all stages of atherosclerosis

Bennett G. Childs et al.

SCIENCE (2016)

Review Oncology

Role of Telomeres and Telomerase in Aging and Cancer

Jerry W. Shay

CANCER DISCOVERY (2016)

Article Medicine, Research & Experimental

HDACs and HDAC Inhibitors in Cancer Development and Therapy

Yixuan Li et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)

Review Medicine, General & Internal

Rapamycin and rapalogs for tuberous sclerosis complex

Teguh H. Sasongko et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2016)

Review Cardiac & Cardiovascular Systems

Protective effects of sirtuins in cardiovascular diseases: from bench to bedside

Stephan Winnik et al.

EUROPEAN HEART JOURNAL (2015)

Article Biochemistry & Molecular Biology

Proteostasis and aging

Susmita Kaushik et al.

NATURE MEDICINE (2015)

Review Multidisciplinary Sciences

Stem cells and healthy aging

Margaret A. Goodell et al.

SCIENCE (2015)

Article Rheumatology

Identification of a Prg4-Expressing Articular Cartilage Progenitor Cell Population in Mice

Elena Kozhemyakina et al.

ARTHRITIS & RHEUMATOLOGY (2015)

Article Rheumatology

The Relationship of Autophagy Defects to Cartilage Damage During Joint Aging in a Mouse Model

Beatriz Carames et al.

ARTHRITIS & RHEUMATOLOGY (2015)

Article Clinical Neurology

Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population

Katherine H. M. Cox et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2015)

Article Multidisciplinary Sciences

Antihyperglycemic mechanism of metformin occurs via the AMPK/LXRα/POMC pathway

Kumsun Cho et al.

SCIENTIFIC REPORTS (2015)

Article Chemistry, Medicinal

Anti-Inflammatory Effects of Vitis thunbergii var. taiwaniana on Knee Damage Associated with Arthritis

Ching-Fent Tsai et al.

JOURNAL OF MEDICINAL FOOD (2014)

Review Clinical Neurology

The Prevalence of Parkinson's Disease: A Systematic Review and Meta-analysis

Tamara Pringsheim et al.

MOVEMENT DISORDERS (2014)

Review Multidisciplinary Sciences

The role of senescent cells in ageing

Jan M. van Deursen

NATURE (2014)

Review Geriatrics & Gerontology

Aging Is Not a Disease: Implications for Intervention

Suresh I. S. Rattan

AGING AND DISEASE (2014)

Review Biochemistry & Molecular Biology

The Hallmarks of Aging

Carlos Lopez-Otin et al.

Article Biochemistry & Molecular Biology

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

Filipe Cabreiro et al.

Article Cardiac & Cardiovascular Systems

Deletion of the ageing gene p66Shc reduces early stroke size following ischaemia/reperfusion brain injury

Remo D. Spescha et al.

EUROPEAN HEART JOURNAL (2013)

Article Neurosciences

Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

Lasse Gliemann et al.

JOURNAL OF PHYSIOLOGY-LONDON (2013)

Review Multidisciplinary Sciences

mTOR is a key modulator of ageing and age-related disease

Simon C. Johnson et al.

NATURE (2013)

Article Multidisciplinary Sciences

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

Guo Zhang et al.

NATURE (2013)

Article Cell Biology

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

Juan Carlos Acosta et al.

NATURE CELL BIOLOGY (2013)

Article Geriatrics & Gerontology

Effect of age on neocortical brain cells in 90+ year old human females-a cell counting study

Katrine Fabricius et al.

NEUROBIOLOGY OF AGING (2013)

Review Pharmacology & Pharmacy

Microglia during development and aging

G. Jean Harry

PHARMACOLOGY & THERAPEUTICS (2013)

Article Cell Biology

Inflammaging: disturbed interplay between autophagy and inflammasomes

Antero Salminen et al.

AGING-US (2012)

Review Oncology

Metformin and breast cancer risk: a meta-analysis and critical literature review

Nananda F. Col et al.

BREAST CANCER RESEARCH AND TREATMENT (2012)

Article Medicine, Research & Experimental

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer

Bruno Bernardes de Jesus et al.

EMBO MOLECULAR MEDICINE (2012)

Article Chemistry, Medicinal

Resveratrol Inhibits Inflammation Induced by Heat-Killed Listeria monocytogenes

Dae-Weon Park et al.

JOURNAL OF MEDICINAL FOOD (2012)

Article Multidisciplinary Sciences

An epigenetic blockade of cognitive functions in the neurodegenerating brain

Johannes Graeff et al.

NATURE (2012)

Article Multidisciplinary Sciences

An Immunosurveillance Mechanism Controls Cancer Cell Ploidy

Laura Senovilla et al.

SCIENCE (2012)

Article Multidisciplinary Sciences

Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model

Mitra Lavasani et al.

NATURE COMMUNICATIONS (2012)

Article Medicine, Research & Experimental

Inflammation in Alzheimer Disease-A Brief Review of the Basic Science and Clinical Literature

Tony Wyss-Coray et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Article Endocrinology & Metabolism

SirT1 Regulates Adipose Tissue Inflammation

Matthew P. Gillum et al.

DIABETES (2011)

Review Dentistry, Oral Surgery & Medicine

Molecular Inflammation as an Underlying Mechanism of the Aging Process and Age-related Diseases

H. Y. Chung et al.

JOURNAL OF DENTAL RESEARCH (2011)

Article Multidisciplinary Sciences

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Darren J. Baker et al.

NATURE (2011)

Article Medicine, General & Internal

Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis

Francis X. McCormack et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Review Multidisciplinary Sciences

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

Douglas R. Green et al.

SCIENCE (2011)

Review Cell Biology

Taking a good look at free radicals in the aging process

Siegfried Hekimi et al.

TRENDS IN CELL BIOLOGY (2011)

Article Endocrinology & Metabolism

Age-associated development of inflammation in Wistar rats: Effects of caloric restriction

Daniel Horrillo et al.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2011)

Article Pathology

Rapamycin Extends Maximal Lifespan in Cancer-Prone Mice

Vladimir N. Anisimov et al.

AMERICAN JOURNAL OF PATHOLOGY (2010)

Review Pathology

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

Jean -Philippe Coppe et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)

Review Biochemistry & Molecular Biology

Impact on DNA Methylation in Cancer Prevention and Therapy by Bioactive Dietary Components

Y. Li et al.

CURRENT MEDICINAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Metformin Suppresses Azoxymethane-Induced Colorectal Aberrant Crypt Foci by Activating AMP-Activated Protein Kinase

Kunihiro Hosono et al.

MOLECULAR CARCINOGENESIS (2010)

Review Pharmacology & Pharmacy

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

Shin-ichiro Imai et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2010)

Review Cell Biology

Neuronal death in Alzheimer's disease and therapeutic opportunities

Rossen Donev et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)

Article Multidisciplinary Sciences

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

David E. Harrison et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

Chong Chen et al.

SCIENCE SIGNALING (2009)

Article Biochemistry & Molecular Biology

Chemokine signaling via the CXCR2 receptor reinforces senescence

Juan C. Acosta et al.

Article Biochemistry & Molecular Biology

AMPK phosphorylation of raptor mediates a metabolic checkpoint

Dana M. Gwinn et al.

MOLECULAR CELL (2008)

Article Multidisciplinary Sciences

Delayed ageing through damage protection by the Arf/p53 pathway

Ander Matheu et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α

Zachary Gerhart-Hines et al.

EMBO JOURNAL (2007)

Article Multidisciplinary Sciences

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur et al.

NATURE (2006)

Article Biophysics

The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin

Cecile Batandier et al.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2006)

Article Multidisciplinary Sciences

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

JG Wood et al.

NATURE (2004)

Article Multidisciplinary Sciences

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

KT Howitz et al.

NATURE (2003)

Article Clinical Neurology

Functional decline in Parkinson disease

J Jankovic et al.

ARCHIVES OF NEUROLOGY (2001)